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TMSClA

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Identification
Molecular formula
C7H18ClNSi
CAS number
49625-78-3
IUPAC name
2-chloro-N-methyl-N-(trimethylsilylmethyl)ethanamine
State
State

2-Chloro-N-methyl-N-(trimethylsilylmethyl)ethanamine is a liquid at room temperature.

Melting point (Celsius)
-83.00
Melting point (Kelvin)
190.15
Boiling point (Celsius)
126.50
Boiling point (Kelvin)
399.65
General information
Molecular weight
165.76g/mol
Molar mass
165.7590g/mol
Density
0.8083g/cm3
Appearence

2-Chloro-N-methyl-N-(trimethylsilylmethyl)ethanamine is typically a clear liquid.

Comment on solubility

Solubility of 2-chloro-N-methyl-N-(trimethylsilylmethyl)ethanamine

When evaluating the solubility of 2-chloro-N-methyl-N-(trimethylsilylmethyl)ethanamine, several factors must be considered that influence its behavior in various solvents. This compound, characterized by its unique structure, may exhibit solubility properties influenced by both its polar and non-polar groups.

Key Factors Affecting Solubility:

  • Polarity: The presence of the chlorine atom and nitrogen functional groups may enhance solubility in polar solvents like water.
  • Hydrophobic Character: The trimethylsilylmethyl group introduces hydrophobic characteristics which may lower solubility in highly polar solvents.
  • Hydrogen Bonding: The nitrogen atom can engage in hydrogen bonding, potentially increasing solubility in protic solvents.

It can be expected that this compound may show variable solubility profiles:

  • Good solubility in polar aprotic solvents (like DMSO or DMF) due to its ability to stabilize the molecular structure.
  • Limited solubility in water owing to its silanol nature which may lead to aggregation effects.
  • Potential solubility in non-polar solvents driven by the trimethylsilyl group, allowing it to dissolve effectively in organic solvents.

Understanding the solubility dynamics of this compound is crucial for practical applications in synthetic chemistry and pharmaceutical formulations. Therefore, empirical solubility studies are essential to determine the optimal solvent or solvent mixture for its effective use.

Interesting facts

Interesting Facts About 2-chloro-N-methyl-N-(trimethylsilylmethyl)ethanamine

2-chloro-N-methyl-N-(trimethylsilylmethyl)ethanamine is a fascinating compound that falls under the category of amines, which are nitrogen-containing organic compounds. Here are some notable points regarding its chemistry and applications:

  • Structure and Function: This compound features a unique combination of a chloro group and a trimethylsilylmethyl group attached to an ethanamine backbone, which can significantly influence its chemical reactivity and interaction with biological systems.
  • Chemical Versatility: The presence of the trimethylsilyl group enhances its potential for use in organic synthesis, particularly in protecting functional groups. This makes it a prime candidate for various reactions, such as nucleophilic substitutions.
  • Utilization in Synthesis: Its structure provides a platform for multiple synthetic pathways, contributing to the production of more complex organic molecules. Chemists often favor such compounds for their ability to facilitate reactions that might be otherwise challenging.
  • Biological Implications: As a modified amine, 2-chloro-N-methyl-N-(trimethylsilylmethyl)ethanamine may have interesting interactions with biological targets. Research into structurally similar compounds has revealed potential pharmacological activities, including effects on neurotransmitter systems.
  • Research and Development: The compound’s unique properties make it a subject of interest in material science and drug design, where it can be utilized for developing novel therapeutic agents or functional materials.

In summary, 2-chloro-N-methyl-N-(trimethylsilylmethyl)ethanamine illustrates how intricate molecular structures can lead to diverse applications in chemistry and biology. As compound synthesis continues to evolve, innovations involving such molecular tools will undoubtedly pave the way for exciting developments in various fields.