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2-Chloro-N-phenylbenzamide

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Identification
Molecular formula
C13H10ClNO
CAS number
1638-60-8
IUPAC name
2-chloro-N-phenyl-benzamide
State
State

At room temperature, 2-Chloro-N-phenylbenzamide is in a solid state.

Melting point (Celsius)
162.00
Melting point (Kelvin)
435.15
Boiling point (Celsius)
379.00
Boiling point (Kelvin)
652.15
General information
Molecular weight
231.67g/mol
Molar mass
231.6690g/mol
Density
1.3070g/cm3
Appearence

2-Chloro-N-phenylbenzamide appears as a white to pale yellow crystalline solid. It is typically encountered in powdered form and is often used in laboratories and chemical research due to its distinctive physicochemical properties.

Comment on solubility

Solubility of 2-chloro-N-phenyl-benzamide

2-chloro-N-phenyl-benzamide, with the chemical formula C13H10ClN1O1, demonstrates an interesting solubility profile that is influenced by its molecular structure.

When discussing the solubility of this compound, it is essential to consider several key factors:

  • Polarity: The presence of the chlorine atom and the amide functional group contributes to the compound's polar characteristics. However, the aromatic rings can enhance hydrophobic interactions.
  • Solvents: 2-chloro-N-phenyl-benzamide is typically soluble in organic solvents such as ethanol, acetone, and dichloromethane, but has limited solubility in water due to its non-polar aromatic regions.
  • Temperature: Increased temperature often enhances the solubility of organic compounds, including this benzamide derivative, as it may overcome the energy barriers for dissolution.

In summary, while 2-chloro-N-phenyl-benzamide exhibits moderate solubility in organic solutions, water remains a challenging medium for this compound. The careful selection of the solvent, with a clear focus on polarity and temperature, will yield the best outcomes for various chemical applications.

Interesting facts

Interesting Facts about 2-chloro-N-phenyl-benzamide

2-chloro-N-phenyl-benzamide is a fascinating compound with various applications and characteristics that make it noteworthy in the field of chemistry. Here are some interesting facts:

  • Pharmaceutical Relevance: This compound is often studied for its potential use in pharmaceutical applications, particularly in drug design and development. Its structure allows it to interact with biological targets, making it a candidate for therapeutic agents.
  • Synthetic Approaches: 2-chloro-N-phenyl-benzamide can be synthesized through various methods, including nucleophilic substitution reactions. This makes it a valuable compound for synthetic chemists working on the development of complex organic molecules.
  • Structure-Activity Relationship: The presence of the chloro group and the phenyl moiety allows for interesting studies in structure-activity relationships (SAR), helping researchers understand how changes in molecular structure can affect biological activity.
  • Industrial Applications: Beyond its pharmaceutical significance, this compound may have applications in agrochemicals or as a dye intermediate, showcasing its versatility in different industries.
  • Research Potential: Ongoing research into amide derivatives like 2-chloro-N-phenyl-benzamide unveils new insights into their enzymatic reactions, interaction with receptors, and overall chemical behavior, contributing to broader scientific knowledge.

In summary, 2-chloro-N-phenyl-benzamide not only has rich synthetic and biological relevance but also serves as a key compound in advancing our understanding of chemical interactions and therapeutic potential. As scientists continue to explore its properties, the scope of its applications may expand even further.

Synonyms
2-chloro-N-phenylbenzamide
2-CHLOROBENZANILIDE
Benzamide, 2-chloro-N-phenyl-
GJ4TC95K9F
NSC 405514
NSC-405514
2-Chloro-N-phenyl-benzamide
AI3-14148
DTXSID90218475
N-PHENYL-O-CHLOROBENZAMIDE
DTXCID10140966
axqviwhaeylglo-uhfffaoysa-n
6833-13-2
o-Chlorobenzanilide
2-Chlorobenzoanilide
Benzanilide, 2-chloro-
2-Chlorobenzoic acid anilide
MFCD00016336
NSC405514
N-phenyl-2-chlorobenzamide
UNII-GJ4TC95K9F
SCHEMBL1203522
CS-D0328
AKOS001314866
FC71223
AS-58936
DB-122127
Z27782611