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2-Chloro-N,N-diethylacetamide

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Identification
Molecular formula
C6H12ClNO
CAS number
96-20-8
IUPAC name
2-chloro-N,N-diethyl-acetamide
State
State

This compound is a liquid at room temperature.

Melting point (Celsius)
-49.00
Melting point (Kelvin)
224.15
Boiling point (Celsius)
223.00
Boiling point (Kelvin)
496.15
General information
Molecular weight
149.62g/mol
Molar mass
149.6230g/mol
Density
1.0349g/cm3
Appearence

2-Chloro-N,N-diethylacetamide is typically a colorless to pale yellow liquid. It has a faint amine-like odor, characteristic of amides and chlorinated hydrocarbons.

Comment on solubility

Solubility of 2-chloro-N,N-diethyl-acetamide

2-chloro-N,N-diethyl-acetamide, with its unique chemical structure, exhibits a noteworthy solubility profile. As a derivative of acetamide, it shows a balance between polar and non-polar characteristics, which influences its behavior in various solvents.

Key points regarding its solubility include:

  • Solvent type: 2-chloro-N,N-diethyl-acetamide is polar in nature, making it soluble in polar solvents such as water.
  • Hydrogen bonding: The presence of the amide group allows for hydrogen bonding interaction, enhancing its solubility in water.
  • Alkyl chains: The diethyl groups contribute to a degree of hydrophobicity, which can limit solubility in highly polarized environments.
  • Temperature effects: Solubility may vary with temperature; generally, increased temperatures favor enhanced solubility.

In summary, 2-chloro-N,N-diethyl-acetamide demonstrates substantial solubility in polar solvents, particularly water, due to the interplay of hydrogen bonding and molecular characteristics. It serves as an example of how chemical structure can fundamentally determine solubility behavior.

Interesting facts

Interesting Facts About 2-chloro-N,N-diethyl-acetamide

2-chloro-N,N-diethyl-acetamide is a fascinating compound with a variety of applications and notable characteristics that capture the interest of both chemists and students alike. Here are some engaging insights about this compound:

  • Chemical Structure: This compound features a unique combination of functional groups that can contribute to its reactivity and properties, making it an intriguing subject for research in organic chemistry.
  • Applications: 2-chloro-N,N-diethyl-acetamide is used in various fields, including:
    • Pharmaceutical industry: Its derivatives may play a role in the development of new medicinal compounds.
    • Agriculture: This compound has potential as a building block for agrochemicals.
  • Synthesis: The synthesis of 2-chloro-N,N-diethyl-acetamide involves several steps. It can be derived from the reaction of acetamide with chloroethyl derivatives, showcasing the use of electrophilic substitution in organic synthesis.
  • Reactivity: The presence of the chloro substituent can influence the compound's reactivity profile, making it a versatile intermediate in organic synthesis, which may further lead to the development of more complex molecules.
  • Study Interest: Due to its unique structure, this compound can be a great case study for students in learning about:
    • Amide formation
    • Substitution reactions
    • The effects of substituents on the stability and reactivity of organic compounds

In summary, 2-chloro-N,N-diethyl-acetamide serves as a compelling example of how specific structural features can dictate the behavior and potential applications of a chemical compound, making it a valuable topic of study in the field of chemistry.

Synonyms
2-Chloro-N,N-diethylacetamide
Acetamide, 2-chloro-N,N-diethyl-
N,N-Diethyl-2-chloroacetamide
Caswell No. 333G
EINECS 219-019-2
N-(Chloroacetyl)diethylamine
BRN 0605866
2TK444LD3S
AI3-23570
NSC-1726
DTXSID7062326
CQQUWTMMFMJEFE-UHFFFAOYSA-
N,N-diethyl-alpha-chloroacetamide
CHLORO-N,N-DIETHYLACETAMIDE
4-04-00-00350 (Beilstein Handbook Reference)
N-(2-CHLOROACETYL)DIETHYLAMINE
DIETHYL-2-CHLOROACETAMIDE, N,N-
2-(DIETHYLAMINO)-2-OXOETHYL CHLORIDE
DTXCID3036818
219-019-2
cqquwtmmfmjefe-uhfffaoysa-n
inchi=1/c6h12clno/c1-3-8(4-2)6(9)5-7/h3-5h2,1-2h3
2315-36-8
N,N-Diethylchloroacetamide
CDEA
N-Chloroacetyldiethylamine
TL 83
NSC 1726
.alpha.-Chloro-N,N-diethylacetamide
Diethylamid kyseliny chloroctove
MFCD00000928
alpha-Chloro-N,N-diethylacetamide
Diethylamid kyseliny chloroctove [Czech]
2-chloro-N,N-diethyl-acetamide
N,N-diethyl chloroacetamide
N,N-diethyl-chloroacetamide
N,N-diethylchloro acetamide
chloroacetic acid dietylamide
UNII-2TK444LD3S
N, N-diethyl chloroacetamide
2-chlor-n,n-diethylacetamide
chloroacetic acid diethylamide
SCHEMBL224316
WLN: G1VN2&2
2-chloro-N,N-diethyl acetamide
monochloroacetic acid diethylamide
NSC1726
monochloroacetic acid diethyl amide
ALBB-025880
BBL005343
STL122974
2-Chloro-N,N-diethylacetamide, 97%
AKOS000120892
AS-10863
DB-046091
CS-0116591
D0483
NS00027367
EN300-20853
F14859
F2190-0235