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Dimethylaminoethyl chloride

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Identification
Molecular formula
C4H10ClN
CAS number
4584-46-7
IUPAC name
2-chloro-N,N-dimethyl-ethanamine
State
State

At room temperature, dimethylaminoethyl chloride is a liquid. It is often used in organic synthesis and should be handled carefully due to its chemical properties.

Melting point (Celsius)
-71.00
Melting point (Kelvin)
202.15
Boiling point (Celsius)
86.80
Boiling point (Kelvin)
359.95
General information
Molecular weight
109.59g/mol
Molar mass
109.5880g/mol
Density
0.9076g/cm3
Appearence

Dimethylaminoethyl chloride is typically a colorless to pale yellow liquid. It can also appear as a slightly viscous liquid due to the presence of impurities or exposure to air.

Comment on solubility

Solubility of 2-chloro-N,N-dimethyl-ethanamine

2-chloro-N,N-dimethyl-ethanamine, with its unique structure, exhibits interesting solubility properties that are essential for its applications in various chemical processes. The solubility of this compound can be influenced by several factors, including:

  • Polarity: Given that this compound contains both an amine group and a chlorine atom, it likely has polar characteristics. Polar compounds typically dissolve well in polar solvents.
  • Hydrogen Bonding: The presence of the amine functional group allows for the possibility of hydrogen bonding, enhancing solubility in water.
  • Temperature: As with many organic compounds, solubility can increase with temperature, allowing for greater dissolution in solvents.

It is often reported that amines like this compound are generally soluble in water, but the presence of chlorides may introduce some complexities. Typical solubility characteristics include:

  1. Soluble in water due to hydrogen bonding.
  2. Varies in non-polar solvents depending on molecular interactions.
  3. Potential for varying solubility at different pH levels due to the ionic nature of the amine when protonated.

Overall, while the solubility of 2-chloro-N,N-dimethyl-ethanamine may be generally favorable in polar environments, the specific conditions such as solvent choice and temperature can significantly impact its behavior. Thus, it is always advisable to conduct solubility tests under intended use conditions.

Interesting facts

Interesting Facts About 2-Chloro-N,N-dimethyl-ethanamine

2-Chloro-N,N-dimethyl-ethanamine, commonly referred to as a derivative of ethylamine, is a compound with significant implications in both synthetic chemistry and pharmaceutical research. Here are some fascinating insights into this chemical:

  • Basic Usage: This compound is primarily used as an intermediate in the synthesis of other chemical products, including pharmaceuticals and agrochemicals. Its versatility makes it a valuable building block in organic chemistry.
  • Biological Relevance: Compounds similar in structure to 2-chloro-N,N-dimethyl-ethanamine often exhibit biological activity. Being an amine, it can participate in various interactions in biological systems, potentially affecting neurotransmitter pathways.
  • Regulatory Aspect: As a chlorinated amine, it may be subject to specific regulations regarding its handling and use, especially in research and industrial settings. Safety protocols are essential to mitigate any risks associated with halogenated compounds.
  • Synthesis: The synthesis of 2-chloro-N,N-dimethyl-ethanamine typically involves the reaction of dimethylamine and a suitable chlorinating agent. This highlights its production methodology as an essential part of understanding its chemical properties.
  • Versatile Applications: Beyond pharmaceuticals, this compound can find applications in areas such as cosmetic formulations or as a reagent in various other organic transformations.

In summary, 2-chloro-N,N-dimethyl-ethanamine serves as an illustrative example of the complexity and utility found within the realm of organic chemistry, showcasing how even simple structures can lead to substantial applications in science and industry. As one might say in the field, "the beauty of chemistry lies in its capacity to connect the simplest molecules to our daily lives."


Synonyms
2-Chloro-N,N-dimethylethanamine
107-99-3
(2-Chloroethyl)dimethylamine
2-Chloroethyldimethylamine
Dimethylaminoethyl chloride
Ethanamine, 2-chloro-N,N-dimethyl-
Nitrogen half mustard
Chloro(dimethylamino)ethane
2-Dimethylaminoethyl chloride
N,N-Dimethylaminoethyl chloride
2-Dimethylaminoethylchloride
N-(2-Chloroethyl)dimethylamine
N,N-Dimethyl-2-chloroethylamine
Dimethyl(2-chloroethyl)amine
2-chloro-N,N-dimethylethylamine
beta-Chloroethyldimethylamine
CCRIS 5796
N,N-Dimethyl(2-chloroethyl)amine
ETHYLAMINE, 2-CHLORO-N,N-DIMETHYL-
EINECS 203-540-7
9UK81G2OHJ
N,N-Dimethylaminoethylchloride
BRN 0605280
1-Dimethylamino-2-chloroethane
2-(Dimethylamino)ethyl chloride
2-chloro-N,N-dimethyl-ethanamine
2-chloro-ethyl-dimethyl-amine
DTXSID2059356
4-04-00-00444 (Beilstein Handbook Reference)
NSC-1917
2-chloro-N,N-dimethylethan-1-amine
NSC-123444
CHLOROETHYL)DIMETHYLAMINE, (2-
N-(2-chloroethyl)-N,N-dimethylamine
UNII-9UK81G2OHJ
(2-Chloro-ethyl)-dimethyl-amine
DMAEC
chloroethyldimethylamine
2-CHLORO-N,N-DIMETHYL-ETHYLAMINE
dimethylaminoethylchloride
dimethylamino ethylchloride
2-chlorodimethylaminoethane
2-dimethylaminoethylchlorid
2-chloroethyl-dimethylamine
(dimethylamino)ethylchloride
dimethylamino ethyl chloride
dimethylamino-ethyl chloride
2-chloro-ethyl dimethylamine
(dimethylamino)ethyl chloride
2-dimethylamino ethylchloride
(2-Chloroethyl)-dimethylamine
SCHEMBL131951
2-(dimethylamino)ethylchloride
2-dimethylamino-ethyl chloride
.beta.-Chloroethyldimethylamine
1-chloro-2-dimethylaminoethane
1-chloro-2dimethylamino-ethane
2-chloro-1-dimethylaminoethane
2-dimethylamino-1-chloroethane
beta-dimethylaminoethyl chloride
1-chloro-2-dimethylamino-ethane
2-chloroethyl-N,N-dimethylamine
CHEMBL3580424
DTXCID5033048
CHEBI:78155
n,n-dimethylamino-2-chloroethane
WQMAANNAZKNUDL-UHFFFAOYSA-
2-chloro-N,N-dimethyl ethanamine
2-chloro-N,N-dimethyl ethylamine
(2-{chloro}-ethyl)-dimethylamine
beta-(Dimethylamino)ethyl chloride
2-Chloro-1-(dimethylamino) ethane
2-Chloro-N,N-dimethylethanamine #
.beta.-(Dimethylamino)ethyl chloride
2-(N,N-dimethylamino)ethyl chloride
STL137774
AKOS005720841
2-(N,N-dimethylamino)-1-chloroethane
BS-12663
DB-007723
NS00023487
D88148
Q27147657
InChI=1/C4H10ClN/c1-6(2)4-3-5/h3-4H2,1-2H3