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Chlorpyrifos

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Identification
Molecular formula
C9H12ClN3
CAS number
122-21-8
IUPAC name
2-chloro-N,N,6-trimethyl-pyrimidin-4-amine
State
State

The compound is generally found in a crystalline solid state at room temperature.

Melting point (Celsius)
42.50
Melting point (Kelvin)
315.65
Boiling point (Celsius)
330.00
Boiling point (Kelvin)
603.15
General information
Molecular weight
214.68g/mol
Molar mass
214.6750g/mol
Density
1.4816g/cm3
Appearence

2-Chloro-N,N,6-trimethyl-pyrimidin-4-amine is typically a colorless to light yellow crystalline solid. Its appearance can vary slightly depending on the form and purity of the sample.

Comment on solubility

Solubility of 2-chloro-N,N,6-trimethyl-pyrimidin-4-amine

Understanding the solubility of 2-chloro-N,N,6-trimethyl-pyrimidin-4-amine is essential for its applications and behavior in various environments. This compound falls under the category of pyrimidine derivatives, which can display diverse solubility profiles depending on the presence of functional groups and their interactions with solvents.

Key Points on Solubility:

  • Polarizability: Being a pyrimidine derivative, the presence of the chloro group introduces polarity, which can enhance solubility in polar solvents like water.
  • Intermolecular Interactions: The amine group can form hydrogen bonds, potentially increasing solubility in alcohols and other hydrogen-bonding solvents.
  • Solvent Compatibility: Solubility can significantly vary when using different solvents; common solvents include ethanol, dimethyl sulfoxide (DMSO), and acetone.

However, it’s important to note that while this compound might be soluble in certain organic solvents, solubility in water can be limited due to its molecular structure.

In summary, the solubility of 2-chloro-N,N,6-trimethyl-pyrimidin-4-amine is influenced by:

  1. The presence of polar functional groups.
  2. The ability to form hydrogen bonds.
  3. The choice of solvent used for dissolution.

Understanding these factors is crucial for using this compound effectively in chemical formulations and reactions.

Interesting facts

Interesting Facts about 2-chloro-N,N,6-trimethyl-pyrimidin-4-amine

2-chloro-N,N,6-trimethyl-pyrimidin-4-amine, a fascinating compound in the realm of pyrimidine derivatives, has garnered significant interest in both medicinal chemistry and agricultural applications. Here are some captivating aspects of this compound:

  • Pyrimidine Backbone: The compound is based on a pyrimidine structure, which is known for its unique six-membered ring containing two nitrogen atoms. This structure is prevalent in various natural and synthetic compounds.
  • Medical Relevance: Compounds related to pyrimidines often serve as *core structures* in pharmaceuticals. They can exhibit activities such as antifungal, antiviral, and anticancer properties, making them vital in drug discovery.
  • Agricultural Use: 2-chloro-N,N,6-trimethyl-pyrimidin-4-amine may also play a role in agricultural chemistry, particularly in the development of herbicides. Its effectiveness in weed management is of considerable interest for enhancing crop yield.
  • Structure-Activity Relationship (SAR): The presence of the chloro group and the trimethyl substitutions on the pyrimidine ring can significantly influence the biological activities of the compound. Understanding these relationships can lead to the design of more effective compounds.
  • Research Potential: Ongoing research into this compound focuses on its reactivity and potential to form novel derivatives. Its ability to easily undergo chemical transformations makes it a valuable candidate for synthetic chemists.

In summary, 2-chloro-N,N,6-trimethyl-pyrimidin-4-amine is a compound with a range of potential applications that extends beyond its basic structure. The exploration of pyrimidine derivatives continues to reveal invaluable insights in both chemistry and biological fields.

Synonyms
CRIMIDINE
535-89-7
Castrix
Crimidin
2-chloro-N,N,6-trimethylpyrimidin-4-amine
Crimidina
2-Chloro-4-dimethylamino-6-methylpyrimidine
Crimidin [German]
Crimidina [Italian]
Caswell No. 188
Crimidine [ISO:BSI]
NSC 2017
W 491
W-491
HSDB 2812
Pyrimidine, 2-chloro-4-(dimethylamino)-6-methyl-
2-Cloro-4-dimetilamino-6-metil-pirimidina
2-Chloro-N,N-6-trimethyl-4-pyrimidinamine
EINECS 208-622-6
2-Chloor-4-dimethylamino-6-methyl-pyrimidine
2-Chloro-4-dimethylamino-6-methyl-pyrimidine
EPA Pesticide Chemical Code 288200
BRN 0127995
UNII-W34R2923T3
2-Chlor-4-dimethylamino-6-methylpyrimidin
AI3-61801
2-Chloro-4-methyl-6-dimethylaminopyrimidine
2-Chloro-N,N,6-trimethylpyrimidin-4-ylamine
CRIMIDINE [ISO]
CRIMIDINE [MI]
NSC-2017
CRIMIDINE [HSDB]
W34R2923T3
2-Chlor-4-dimethylamino-6-methylpyrimidin [German]
2-Cloro-4-dimetilamino-6-metil-pirimidina [Italian]
2-Chloor-4-dimethylamino-6-methyl-pyrimidine [Dutch]
DTXSID0041800
2-Chloro-4-(dimethylamino)-6-methylpyrimidine
2-Chloro-4-methyl-6-(dimethylamino)pyrimidine
(2-chloro-6-methylpyrimidin-4-yl)dimethylamine
2-CHLORO-N,N,6-TRIMETHYL-4-PYRIMIDINAMINE
4-25-00-02184 (Beilstein Handbook Reference)
CRIMIDIN (GERMAN)
CRIMIDINA (ITALIAN)
2-CHLOOR-4-DIMETHYLAMINO-6-METHYL-PYRIMIDINE (DUTCH)
2-CLORO-4-DIMETILAMINO-6-METIL-PIRIMIDINA (ITALIAN)
CRIMITOX
DTXCID8021800
2Cloro4dimetilamino6metilpirimidina
2Chlor4dimethylamino6methylpyrimidin
2ChloroN,N6trimethyl4pyrimidinamine
2Chloor4dimethylamino6methylpyrimidine
2Chloro4dimethylamino6methylpyrimidine
2Chloro4methyl6dimethylaminopyrimidine
2ChloroN,N,6trimethylpyrimidin4ylamine
4Pyrimidinamine, 2chloroN,N,6trimethyl
Pyrimidine, 2chloro4(dimethylamino)6methyl
Pyrimidine, 2-chloro-4-dimethylamino-6-methyl
2-CHLORO-N,N,6-TRIMETHYL-4-PYRIMIDIN-4-AMINE
208-622-6
hjiupfpiebpyie-uhfffaoysa-n
4-Pyrimidinamine, 2-chloro-N,N,6-trimethyl-
CHEBI:82258
2-Chloro-4-(dimethylamino)-6-methyl-pyrimidine
(2-chloro-6-methyl-pyrimidin-4-yl)-dimethyl-amine
SCHEMBL432253
CHEMBL1607733
4-Pyrimidinamine,N,6-trimethyl-
NSC2017
MFCD00055517
STK377491
AKOS005177522
WLN: T6N CNJ BG DN1&1 F1
Crimidine 10 microg/mL in Acetonitrile
NCGC00166162-01
AS-54836
DB-071707
NS00004032
2-chloro-4-dimethylamino-6-methyl pyrimidine
Crimidine, PESTANAL(R), analytical standard
EN300-27754
C19138
C67432
W10442
2-CHLORO-N,6-TRIMETHYL-4-PYRIMIDINAMINE
A853931
Q2645488
F1905-0504