Skip to main content

Chloroacetic acid

ADVERTISEMENT
Identification
Molecular formula
C2H3ClO2
CAS number
79-11-8
IUPAC name
2-chloroacetic acid
State
State

At room temperature, chloroacetic acid is typically found in a solid state with a crystalline structure.

Melting point (Celsius)
61.20
Melting point (Kelvin)
334.40
Boiling point (Celsius)
189.30
Boiling point (Kelvin)
462.40
General information
Molecular weight
94.50g/mol
Molar mass
94.4990g/mol
Density
1.5800g/cm3
Appearence

Chloroacetic acid is a white, crystalline solid. It is known for its pungent odor and can appear in the form of hygroscopic crystals or crystalline powder.

Comment on solubility

Solubility of 2-Chloroacetic Acid (C2H3ClO2)

2-Chloroacetic acid, a chlorinated derivative of acetic acid, exhibits unique solubility characteristics that warrant attention. Its ability to dissolve in various solvents is influenced by its molecular structure and functional groups. Here are some key points regarding the solubility of this compound:

  • Water Solubility: 2-Chloroacetic acid is highly soluble in water, due to its ability to form hydrogen bonds with water molecules. This makes it an excellent candidate for aqueous reactions.
  • Organic Solvents: Besides water, this compound is also soluble in organic solvents such as ethanol and acetone, which further enhances its versatility in chemical applications.
  • Effect of Temperature: The solubility of 2-chloroacetic acid tends to increase with rising temperatures, allowing more of the compound to dissolve at elevated temperatures.
  • Concentration Factors: The solubility can be influenced by the presence of other solutes and can vary depending on the concentration of the solution.

Overall, 2-chloroacetic acid showcases significant solubility properties making it important in various chemical processes. Its high solubility in water can be particularly advantageous in metabolic studies and organic synthesis.

Interesting facts

Interesting Facts About 2-Chloroacetic Acid

2-Chloroacetic acid is an intriguing compound with several notable characteristics and applications. This halogenated acetic acid derivative plays a vital role in organic chemistry and industry. Here are some interesting insights:

  • Reactivity: 2-Chloroacetic acid is known for its high reactivity, particularly in nucleophilic substitution reactions. This makes it a valuable intermediate in the synthesis of various chemical compounds.
  • Applications: It serves as a precursor for the production of numerous agrochemicals, pharmaceuticals, and dyes, showcasing its versatility in different sectors:
    • Herbicides and pesticides
    • Pharmaceuticals like glycine and amino acids
    • Textile dyes
  • Biochemical Importance: In biochemistry, 2-chloroacetic acid has been utilized to study metabolic pathways and enzyme reactivity, highlighting its significance in laboratory research.
  • Safety Considerations: While 2-chloroacetic acid is useful, it’s crucial to handle it with care due to its corrosive nature and potential health hazards. Proper safety measures and protective equipment should always be used when working with this compound.

In summary, 2-chloroacetic acid represents a key compound in various fields, reflecting the intricate relationship between simple chemical structures and their extensive real-world applications. Its chemical properties and reactivity continue to provide valuable insights into advanced synthetic methodologies and applications.

Synonyms
chloroacetic acid
Monochloroacetic acid
79-11-8
2-chloroacetic acid
Chloracetic acid
Chloroethanoic acid
Acetic acid, chloro-
Acide chloracetique
Monochloroethanoic acid
Monochloracetic acid
Monochloorazijnzuur
Monochloressigsaeure
Acidomonocloroacetico
2-chloro-acetic acid
Acide monochloracetique
Chloroacetic acid, solid
Acide chloroacetique
Kyselina chloroctova
Acetocaustin
Chloroacetic
2-chloro-ethanoic acid
Caswell No. 179B
Chloroacetic acid [BSI:ISO]
Acetic acid, 2-chloro-
.alpha.-Chloroacetic acid
NSC 142
Monochloorazijnzuur [Dutch]
NCI-C60231
Acide chloracetique [French]
Kyselina chloroctova [Czech]
monochloro acetic acid
Monochloressigsaeure [German]
Acide chloroacetique [French]
alpha-Chloroacetic acid
Acidomonocloroacetico [Italian]
CCRIS 2117
HSDB 939
Acide monochloracetique [French]
Chloroacetic acid, molten
Monochloroacetic acid [BSI:ISO]
Acide chloracetique [ISO-French]
Chloroacetic acid (80% or less)
chloro-acetic acid
EINECS 201-178-4
Acetocaustin (TN)
EPA Pesticide Chemical Code 279400
UNII-5GD84Y125G
BRN 0605438
CH2ClCOOH
DTXSID4020901
CHEBI:27869
AI3-25035
NSC-142
5GD84Y125G
CHLOROACETIC-ACID
alpha-chloro-acetic acid
MFCD00002683
DTXCID20901
Monochloracetic acidacide monochloracetique
Chloroacetic acid, liquid
EC 201-178-4
4-02-00-00474 (Beilstein Handbook Reference)
CHLOROACETIC ACID CRYSTALLINE
Chloroacetic acid, molten [UN3250] [Poison]
Chloroacetic acid, solid [UN1751] [Poison]
Acide chloracetique (ISO-French)
MONOCHLOROACETIC ACID (MART.)
MONOCHLOROACETIC ACID [MART.]
sJPhLQDIKTp@
MCAA
UN1750
UN1751
UN3250
Chloressigsauer
Chlorethansauere
CHLOROACETIC ACID, ACS
cloroacetic acid
chloro acetic acid
Monochloor azijnzuur
R3W
ClCH2COOH
monochloro-acetic acid
Acidomono chloroacetico
Acide monochloroacetique
Chloroacetic acid, 99%
Chloroacetic acid, solid [UN1751] [Poison]
bmse000367
WLN: QV1G
Chloroacetic acid, molten [UN3250] [Poison]
Chloroacetic acid, >=99%
NCIOpen2_002217
Chloroacetic acid, ACS grade
MLS001065621
BIDD:ER0630
CHEMBL14090
CHLOROACETIC ACID [MI]
NSC142
CHLOROACETIC ACID [ISO]
Chloroacetic acid, solid (dot)
CHLOROACETIC ACID [HSDB]
FOCAUTSVDIKZOP-UHFFFAOYSA-
CHLOROACETIC ACID [VANDF]
BCP20585
MSK70013
NSC42970
STR00326
Tox21_201114
BBL037260
LMFA01090068
MONOCHLOROACETIC ACID [VANDF]
NSC-42970
STL197882
Chloroacetic acid, analytical standard
AKOS000118920
MONOCHLOROACETIC ACID [WHO-DD]
UN 1751
CAS-79-11-8
NCGC00091473-01
NCGC00091473-02
NCGC00091473-03
NCGC00258666-01
1ST70013
SMR000568484
Chloroacetic acid, for synthesis, 99.0%
Chloroacetic acid, ACS reagent, >=99.0%
Chloroacetic acid, purum, >=97.0% (T)
C2123
NS00003112
Chloroacetic acid, puriss., >=99.0% (T)
EN300-16767
C06755
D07677
Chloroacetic acid, JIS special grade, >=99.0%
Q409013
Chloroacetic acid, PESTANAL(R), analytical standard
F2190-0289
InChI=1/C2H3ClO2/c3-1-2(4)5/h1H2,(H,4,5)
Chloroacetic acid 1000 microg/mL in Methyl-tert-butyl ether
201-178-4