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2-Chloroacetonitrile

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Identification
Molecular formula
C2H2ClN
CAS number
107-14-2
IUPAC name
2-chloroacetonitrile
State
State

2-Chloroacetonitrile is in a liquid state at room temperature.

Melting point (Celsius)
-65.00
Melting point (Kelvin)
208.15
Boiling point (Celsius)
126.00
Boiling point (Kelvin)
399.15
General information
Molecular weight
73.50g/mol
Molar mass
73.4980g/mol
Density
1.1950g/cm3
Appearence

2-Chloroacetonitrile is a colorless, clear liquid. It has a pungent and acrid odor.

Comment on solubility

Solubility of 2-Chloroacetonitrile

2-chloroacetonitrile, with the chemical formula C2H2ClN, exhibits intriguing solubility characteristics that make it noteworthy in various chemical applications. Its solubility behaviors can be summarized as follows:

  • Polar Solvents: 2-chloroacetonitrile is soluble in polar solvents such as water due to its polar nature arising from the presence of both a nitrile group and chlorinated carbon.
  • Organic Solvents: It is also readily soluble in organic solvents like acetone, ethanol, and ether, facilitating its use in organic synthesis and various chemical reactions.
  • Temperature Dependency: The solubility of 2-chloroacetonitrile may increase with temperature, making it important to consider thermal conditions when preparing solutions.

As with many compounds, the solubility of 2-chloroacetonitrile can significantly influence its reactivity and utility in synthesis processes. Understanding its solubility is crucial for chemists who aim to manipulate this compound effectively in laboratory settings.

Interesting facts

Interesting Facts about 2-Chloroacetonitrile

2-Chloroacetonitrile is an intriguing organic compound that has garnered attention in various scientific fields. Here are some noteworthy aspects:

  • Applications in Synthesis: This compound plays a vital role as an intermediate in the synthesis of numerous pharmaceuticals and agrochemicals. Its unique functional groups make it a building block for more complex molecules.
  • Reactivity: 2-Chloroacetonitrile is particularly reactive due to the presence of both a nitrile functional group and a chlorine atom. This reactivity can be harnessed for nucleophilic substitution reactions, making it useful in organic synthesis.
  • Biological Activity: Compounds in the nitrile family, including 2-chloroacetonitrile, have shown varying biological activities and can serve as important precursors in the development of novel medicines.
  • Environmental Considerations: While 2-chloroacetonitrile has industrial applications, it is essential to consider its environmental impact. Understanding how such compounds degrade or persist in the environment is crucial for sustainable chemistry practices.

Moreover, the structural arrangement of 2-chloroacetonitrile contributes to its chemical properties and behavior in different reactions. The presence of the chlorine atom can influence reaction rates and pathways, lending an air of complexity to its chemistry. As quoted by renowned chemists, "The magic of organic synthesis lies in the interplay of simple compounds to create complex realities."

In summary, 2-chloroacetonitrile exemplifies how a simple chemical structure can have vast implications in synthesis, reactivity, and environmental chemistry. Understanding such compounds not only broadens our knowledge but also paves the way for innovation in chemical research.

Synonyms
CHLOROACETONITRILE
107-14-2
2-Chloroacetonitrile
Chloracetonitrile
Acetonitrile, chloro-
Monochloroacetonitrile
Chloromethyl cyanide
Chloroethanenitrile
alpha-Chloroacetonitrile
Monochloromethyl cyanide
USAF KF-5
NSC 6180
CCRIS 2670
HSDB 6317
Acetonitrile, 2-chloro-
.alpha.-Chloroacetonitrile
UNII-CN524K9DXD
2chloroacetonitrile
EINECS 203-467-0
CN524K9DXD
BRN 0506028
CH2ClCN
DTXSID7021524
AI3-52205
NSC-6180
DTXCID301524
CHEBI:82416
CHLOROACETONITRILE [HSDB]
CHLOROACETONITRILE [IARC]
ACETIC ACID,CHLORO,NITRILE
4-02-00-00492 (Beilstein Handbook Reference)
MFCD00001885
UN 2668
CHLOROACETONITRILE (IARC)
Chloroactonitrile
Chloro-acetonitrile
Chloroethane Nitrile
C2H2ClN
UN2668
chloro acetonitrile
chloroaceto nitrile
2-cloroacetonitrile
cyanomethyl chloride
acetonitrile, chloro
2-chloro-acetonitrile
alphaChloroacetonitrile
ClCH2CN
CHLOROCYANOMETHANE
Chloroacetonitrile, 99%
WLN: NC1G
CHLOROMETHYL, CYANIDE
CHEMBL3187297
NSC6180
BCP27602
Tox21_200957
STL185582
AKOS000118818
NCGC00248886-01
NCGC00258510-01
CAS-107-14-2
Chloroacetonitrile [UN2668] [Poison]
DB-059563
Chloroacetonitrile, purum, >=99.0% (GC)
NS00008099
EN300-19495
A15096
C19360
Q2196683
F2190-0287
203-467-0
694-285-4