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2-Chloroacridin-9-amine

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Identification
Molecular formula
C13H9ClN2
CAS number
30472-88-1
IUPAC name
2-chloroacridin-9-amine
State
State

At room temperature, 2-Chloroacridin-9-amine is in a solid state. It is generally handled as a powder or in crystal form in laboratory settings.

Melting point (Celsius)
168.00
Melting point (Kelvin)
441.15
Boiling point (Celsius)
433.00
Boiling point (Kelvin)
706.15
General information
Molecular weight
228.68g/mol
Molar mass
228.6680g/mol
Density
1.3920g/cm3
Appearence

2-Chloroacridin-9-amine typically appears as a crystalline solid with a light yellow to pale yellow coloration. The compound often exists in powder or crystalline form.

Comment on solubility

Solubility of 2-chloroacridin-9-amine

2-chloroacridin-9-amine exhibits interesting solubility characteristics that can be insightful for various applications. Here are some key points regarding its solubility:

  • Solvent Dependence: The solubility of 2-chloroacridin-9-amine can vary significantly depending on the solvent used. Typically, it is more soluble in organic solvents such as ethanol and dichloromethane.
  • Polarity Influence: Due to the presence of both aromatic and amine functional groups, its solubility is influenced by the polarity of the solvent. Generally, higher polarity solvents can enhance solubility.
  • Temperature Effects: As with many compounds, increasing the temperature often aids in solubilizing 2-chloroacridin-9-amine, leading to a better dissolution rate in the chosen solvent.
  • Crystallization Behavior: Understanding how 2-chloroacridin-9-amine crystallizes from various solvents can provide insights into its solubility and potential for use in specific applications.

In summary, while the solubility of 2-chloroacridin-9-amine is significantly enhanced in polar organic solvents and can be affected by temperature changes, it is essential to conduct thorough experiments to determine the precise solubility profiles suitable for the intended use. As the saying goes, "The right solvent can make all the difference."

Interesting facts

Interesting Facts about 2-Chloroacridin-9-amine

2-Chloroacridin-9-amine is a fascinating organic compound that has drawn interest in various fields, particularly in medicinal chemistry and material science. Below are some noteworthy aspects of this compound:

  • Structural Significance: The compound features a chlorinated acridine structure, which is notable for its planar aromatic ring system. This configuration contributes to its unique electronic properties and enables it to intercalate with DNA, making it significant in cancer research.
  • Biological Activity: Some studies have shown that compounds similar to 2-chloroacridin-9-amine exhibit anti-cancer properties. Their ability to interact with nucleic acids opens avenues for the development of novel chemotherapy agents.
  • Versatile Applications: Beyond medicinal applications, 2-chloroacridin-9-amine may have utility in the manufacture of luminescent materials and fluorescent dyes, expanding its importance in both science and industry.
  • Synthesis Strategies: The synthesis of 2-chloroacridin-9-amine can be achieved through a variety of methods, with each approach offering unique insights into chemical reactivity and transformation. Exploring these synthesis pathways provides valuable educational opportunities for chemistry students.
  • Research Potential: The ongoing investigation into its chemical behavior continues to reveal new facets of 2-chloroacridin-9-amine. As researchers endeavor to synthesize derivatives and analogs, this compound remains a subject of vibrant scientific exploration.

In summary, 2-chloroacridin-9-amine represents a compelling junction of chemistry, biology, and materials science, encouraging further inquiries into its properties and applications.

Synonyms
9-Amino-2-chloroacridine
23250-39-7
ACRIDINE, 9-AMINO-2-CHLORO-
CCRIS 7986
5-Amino-3-chloroacridine (European)
BRN 0173172
DTXSID40177821
5-22-11-00035 (Beilstein Handbook Reference)
RefChem:317139
DTXCID00100312
TCMDC-132029
2-chloroacridin-9-amine
CHEMBL147657
SCHEMBL11057550