Skip to main content

2-chloroethyl 2-fluoroacetate

ADVERTISEMENT
Identification
Molecular formula
C4H6ClFO2
CAS number
689-06-7
IUPAC name
2-chloroethyl 2-fluoroacetate
State
State

At room temperature, 2-chloroethyl 2-fluoroacetate remains in a liquid state, making it useful for various applications in chemical synthesis where a liquid starting material is advantageous.

Melting point (Celsius)
-60.00
Melting point (Kelvin)
213.15
Boiling point (Celsius)
149.00
Boiling point (Kelvin)
422.15
General information
Molecular weight
140.54g/mol
Molar mass
140.5390g/mol
Density
1.3380g/cm3
Appearence

2-Chloroethyl 2-fluoroacetate is a clear, colorless liquid. Its appearance is typical of many organic solvents, with no notable color or particulates present in a pure state.

Comment on solubility

Solubility of 2-chloroethyl 2-fluoroacetate

The solubility of 2-chloroethyl 2-fluoroacetate presents fascinating aspects worth discussing. This compound, characterized by its unique functional groups, displays a variable solubility profile depending on the solvent used. Here are some key points to consider:

  • Polar Solvents: 2-chloroethyl 2-fluoroacetate tends to be more soluble in polar solvents such as water and alcohols. This solubility can be attributed to the presence of polar bonds within the molecule that interact favorably with the solvent molecules.
  • Non-Polar Solvents: Conversely, in non-polar solvents like hexane or toluene, the solubility of this compound decreases significantly. The lack of polarity leads to inadequate interactions, hence poor solubility.
  • Temperature Effects: Temperature can also influence solubility. Increasing the temperature may increase the solubility of 2-chloroethyl 2-fluoroacetate in polar solvents, as it can enhance molecular movement and interactions.
  • pH Influence: As with many organic compounds, the pH of the solution can impact solubility—especially in biologically relevant environments. The state of ionization can alter interactions with the solvent.

In summary, the solubility of 2-chloroethyl 2-fluoroacetate is predominantly influenced by the solvent's polarity, temperature, and the medium's pH level. Consequently, understanding these factors is essential for applications in synthetic and medicinal chemistry.

Interesting facts

Interesting Facts about 2-Chloroethyl 2-Fluoroacetate

2-Chloroethyl 2-fluoroacetate is a compound of great interest in both organic chemistry and medicinal chemistry due to its intriguing structure and potential applications. Here are some fascinating aspects of this compound:

  • Reactivity: The presence of both a chloro and a fluoro group makes this compound a unique building block for the synthesis of more complex molecules. Its reactivity can be harnessed in various chemical reactions, paving the way for innovative synthetic pathways.
  • Biological Applications: Compounds similar to 2-chloroethyl 2-fluoroacetate have garnered attention for potential therapeutic uses. They may exhibit significant biological activity, influencing processes such as cellular signaling or enzyme inhibition.
  • Structure-Activity Relationship (SAR): Understanding how the different halogen substituents affect the compound's reactivity and biological properties is crucial. This analysis can inform synthesis strategies and improve drug design.
  • Environmental Impact: As with many halogenated compounds, the environmental fate and toxicity of 2-chloroethyl 2-fluoroacetate are important considerations. Researchers often study these compounds to ensure that they do not pose significant risks to ecosystems.
  • Mechanisms of Action: Ongoing studies are shedding light on how this compound interacts at the molecular level, offering insights into its mechanisms of action and making it a subject of interest for various scientific inquiries.

Overall, 2-chloroethyl 2-fluoroacetate is not just another compound; it represents the synergy of scientific curiosity and innovation. As we continue to uncover its properties and potential, it stands to contribute significantly to both academic research and practical applications in chemistry.

Synonyms
2-Chloroethyl fluoroacetate
1537-62-8
2-chloroethyl 2-fluoroacetate
ACETIC ACID, FLUORO-, (2-CHLOROETHYL) ESTER
beta-Chloroethyl fluoroacetate
TL 671
BRN 1749279
2-Chlorethylester kyseliny fluoroctove [Czech]
2-Chlorethylester kyseliny fluoroctove
DTXSID60165407
AKOS006385310
fluoroacetic acid, 2-chloroethyl ester