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2-chloroethyl 2-phenylacetate

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Identification
Molecular formula
C10H11ClO2
CAS number
122-01-0
IUPAC name
2-chloroethyl 2-phenylacetate
State
State

At room temperature, 2-chloroethyl 2-phenylacetate is in a liquid state. It is typically stored in sealed containers to prevent any interaction with atmospheric moisture or contaminants.

Melting point (Celsius)
-38.00
Melting point (Kelvin)
235.15
Boiling point (Celsius)
262.00
Boiling point (Kelvin)
535.15
General information
Molecular weight
198.64g/mol
Molar mass
198.6420g/mol
Density
1.1317g/cm3
Appearence

2-Chloroethyl 2-phenylacetate is typically a colorless liquid. It can also be described as almost oily in appearance. The substance may emit a slight aromatic odor.

Comment on solubility

Solubility of 2-chloroethyl 2-phenylacetate

2-chloroethyl 2-phenylacetate, with the chemical formula C10H11ClO2, exhibits unique solubility characteristics that can be influenced by various factors. Understanding the solubility profile of this compound is essential for its applications in chemical synthesis and formulation. Here are some key points regarding its solubility:

  • Polar and Non-Polar Solubility: As an ester, 2-chloroethyl 2-phenylacetate may show limited solubility in water due to its organic structure. However, it is expected to be more soluble in non-polar organic solvents.
  • Temperature Dependence: The solubility of this compound can vary with temperature. Typically, increased temperature can enhance solubility in organic solvents.
  • pH Sensitivity: The solubility may be affected by the pH of the solution. In more acidic or basic environments, hydrolysis or other reactions could alter its solubility.
  • Alkyl Chain Influence: The presence of the chloroethyl group contributes to the overall hydrophobic character of the molecule, influencing its interaction with polar solvents.

To summarize, while 2-chloroethyl 2-phenylacetate is likely to demonstrate poor solubility in water, it is anticipated to be soluble in a range of organic solvents, making it a versatile compound in various chemical contexts. As we examine solubility further, we can appreciate how molecular structure significantly impacts the interactions with solvents.

Interesting facts

Interesting Facts about 2-chloroethyl 2-phenylacetate

2-chloroethyl 2-phenylacetate is a fascinating compound that has become significant in various fields of chemistry, particularly in organic synthesis and medicinal chemistry. Here are some intriguing aspects of this compound:

  • Functional Groups: This compound features both a chloro and an ester functional group, which makes it a versatile intermediate in organic reactions.
  • Reactivity: Due to the presence of the chloro group, 2-chloroethyl 2-phenylacetate is capable of undergoing nucleophilic substitution reactions. This reactivity is essential in the synthesis of other complex organic molecules.
  • Applications: It has been utilized in the synthesis of various pharmaceutical agents, showcasing its role in drug development and design. The presence of the phenyl group aids in enhancing the biological activity of derived compounds.
  • Research Interest: As scientists continue to explore its properties, 2-chloroethyl 2-phenylacetate is a subject of ongoing research for potential applications in the development of cancer therapeutics.
  • Structure Complexity: The unique structure of this compound allows for stereochemical variations, contributing to its importance in studies related to chirality in organic chemistry.

In summary, 2-chloroethyl 2-phenylacetate serves as a crucial building block in organic synthesis, with its intriguing structure and reactivity opening doors for innovative research and applications in medicine and beyond.

Synonyms
943-59-9
ACETIC ACID, PHENYL-, 2-CHLOROETHYL ESTER
2-chloroethyl 2-phenylacetate
2-Chloroethyl phenylacetate
BRN 1948802
b-chloroethyl phenylacetate
2-Chloroethyl phenyl acetate
3-09-00-02178 (Beilstein Handbook Reference)
SCHEMBL10836287
DTXSID60241412
IFAWZYKLULDJQC-UHFFFAOYSA-N
Phenylacetic acid, 2-chloroethyl ester
Phenyl-acetic acid 2-chloro-ethyl ester