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Cevimeline hydrochloride

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Identification
Molecular formula
C10H21Cl2N
CAS number
153504-70-2
IUPAC name
2-chloroethyl-(cyclohexylmethyl)-ethyl-ammonium;chloride
State
State

At room temperature, Cevimeline hydrochloride is in a solid state. It is commonly encountered as a crystalline powder, making it easy to handle in various pharmaceutical preparations.

Melting point (Celsius)
140.00
Melting point (Kelvin)
413.15
Boiling point (Celsius)
285.00
Boiling point (Kelvin)
558.15
General information
Molecular weight
263.23g/mol
Molar mass
263.2330g/mol
Density
1.0787g/cm3
Appearence

Cevimeline hydrochloride typically appears as a white to off-white crystalline powder. Its crystalline nature gives it a distinctly solid form that can range from small granules to larger, more compact crystals, depending on its processing.

Comment on solubility

Solubility of 2-chloroethyl-(cyclohexylmethyl)-ethyl-ammonium chloride

The solubility of 2-chloroethyl-(cyclohexylmethyl)-ethyl-ammonium chloride can be quite intriguing due to its specific structural characteristics. This compound is a quaternary ammonium salt, which is known to impact its interactions with solvents.

In general, quaternary ammonium salts tend to exhibit the following solubility properties:

  • Water Solubility: Many quaternary ammonium compounds are soluble in water due to their ionic nature, but the solubility can vary significantly based on the size and structure of the alkyl groups.
  • Solvent Dependence: These compounds are often soluble in organic solvents like alcohols and ethers, depending on the length and branching of the alkyl chains.
  • Temperature Effects: Increasing temperature typically enhances the solubility of these salts in various solvents.

In the case of 2-chloroethyl-(cyclohexylmethyl)-ethyl-ammonium chloride, the presence of the chlorinated ethyl group may aid in its water solubility, while the cyclohexylmethyl group could introduce sterics that might hinder solubility in more polar solvents. Thus, one might summarize its solubility characteristics as:

  1. Reasonably soluble in water due to the ionic ammonium component.
  2. Varies in solubility with different organic solvents, likely showing a preference for non-polar environments.
  3. Temperature could play a significant role in enhancing solubility.

As such, exploring the solubility of this compound in various solvents can provide insights into its chemical behavior and its potential applications.

Interesting facts

Interesting Facts about 2-Chloroethyl-(cyclohexylmethyl)-ethyl-ammonium Chloride

2-Chloroethyl-(cyclohexylmethyl)-ethyl-ammonium chloride is a fascinating compound within the realm of organic chemistry, particularly due to its structural complexity and potential applications. Here are some intriguing aspects:

  • Quaternary Ammonium Salt: This compound is classified as a quaternary ammonium salt, which is a key category in organic chemistry. These salts often exhibit surfactant properties, making them useful in various applications from detergents to disinfectants.
  • Biological Significance: Research has suggested that derivatives of ammonium salts can have antimicrobial properties. This raises interesting questions about the potential medical applications of this compound, especially in drug formulation or as a biocide.
  • Structural Diversity: The presence of the cyclohexylmethyl group adds a layer of steric hindrance. This can influence the compound's reactivity and may lead to unique interactions with other molecules.
  • Potential Applications: Compounds of this type are often explored in the development of controlled-release drug delivery systems. Their ability to interact with biological membranes could provide pathways for innovative therapeutic strategies.
  • Historical Context: Quaternary ammonium compounds have been a focus in chemistry since the early 20th century, with evolving applications throughout the decades, particularly in the fields of pharmacology and material science.
  • Environmental Implications: With growing concerns about environmental toxicity, studying the degradability and ecotoxicological effects of such compounds is essential. Understanding those aspects can lead to the development of safer, more sustainable alternatives.

In summary, 2-chloroethyl-(cyclohexylmethyl)-ethyl-ammonium chloride stands out not only for its complex structure but also for its multifaceted roles in chemical research and potential practical applications. As chemists and researchers continue to unpack its mysteries, we may find even more uses for this intriguing compound!

Synonyms
GD 131 hydrochloride
21658-44-6
NSC 11471
RefChem:1085735
2-Chloro-N-(cyclohexylmethyl)diethylamine hydrochloride
N-(2-Chloroethyl)-N-cyclohexylmethylethylamine hydrochloride
Cyclohexanemethanamine, N-(2-chloroethyl)-N-ethyl-, hydrochloride
ETHYLAMINE, N-(2-CHLOROETHYL)-N-(CYCLOHEXYLMETHYL)-, HYDROCHLORIDE
Cyclohexanemethylamine, N-(2-chloroethyl)-N-ethyl-, hydrochloride
Cyclohexanemethanaminium, N-(2-chloroethyl)-N-ethyl-, chloride (1:1)