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2-Chloroethyl methanesulfonate

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Identification
Molecular formula
C3H7ClO3S
CAS number
2941-64-2
IUPAC name
2-chloroethyl methanesulfonate
State
State

At room temperature, 2-chloroethyl methanesulfonate is in a liquid state. It remains stable under normal conditions but should be stored in a cool, dry place to prevent decomposition.

Melting point (Celsius)
-20.00
Melting point (Kelvin)
253.15
Boiling point (Celsius)
210.00
Boiling point (Kelvin)
483.15
General information
Molecular weight
160.61g/mol
Molar mass
160.6110g/mol
Density
1.3594g/cm3
Appearence

2-Chloroethyl methanesulfonate is a colorless to pale yellow liquid. It has an oily consistency and is often described as possessing a faint, somewhat sweet odor.

Comment on solubility

Solubility of 2-chloroethyl methanesulfonate

2-chloroethyl methanesulfonate (C3H7ClO3S) is an organic compound that is known for its relatively moderate solubility characteristics. The solubility of this compound can be influenced by several factors:

  • Polarity: As a compound containing both chlorine and a sulfonate group, 2-chloroethyl methanesulfonate exhibits polar characteristics, making it more soluble in polar solvents.
  • Solvent Choice: It shows good solubility in solvents such as water and alcohols, enhancing its usability in various chemical reactions, especially in aqueous systems.
  • Temperature Effects: Like many chemical compounds, the solubility may increase with temperature, suggesting that higher temperatures could facilitate its dissolution in a solvent.

It is important to keep in mind that while 2-chloroethyl methanesulfonate is soluble in certain solvents, its behavior in a mixture will depend significantly on the solvent characteristics as well as the presence of other solutes. In summary, the ability of 2-chloroethyl methanesulfonate to dissolve is not only a factor of its chemical structure but also the surrounding environment. "Understanding solubility is paramount for anticipating chemical behavior and reactivity."

Interesting facts

Interesting Facts About 2-Chloroethyl Methanesulfonate

2-Chloroethyl methanesulfonate (often abbreviated as CEMS) is a fascinating compound that falls within the category of alkylating agents, widely recognized for its unique properties and applications in chemical and biological research.

Key Characteristics

  • Biological Significance: One of the most notable uses of 2-chloroethyl methanesulfonate is its role as a reagent in medicinal chemistry, particularly in the synthesis of sulfur-containing compounds.
  • Alkylating Agent: CEMS is considered an alkylating agent, which means it can add alkyl groups to various molecules, a process critical in DNA modification and studying mutagenesis.
  • Industrial Applications: Beyond its laboratory significance, this compound is also utilized in the production of pharmaceutical intermediates, significantly contributing to drug development processes.

Historical Context

The exploration of 2-chloroethyl methanesulfonate dates back several decades and has garnered attention due to its effectiveness in serving as a molecular tool. Its mechanisms of action have been critical in understanding how certain reactions alter chemical structures and biological functions.

Safety Considerations

As with many alkylating agents, safety is paramount. Due to its reactivity, proper handling procedures must be followed to mitigate risks such as:

  • Potential mutagenicity
  • Corrosive nature on contact with skin or mucous membranes
  • Environmental impact necessitating careful disposal methods

In summary, 2-chloroethyl methanesulfonate serves as a powerful compound in both academic research and industrial applications. As chemists and students delve deeper into its mechanisms and uses, the compound continues to be a vital asset in the field of chemistry.

Synonyms
2-CHLOROETHYL METHANESULFONATE
3570-58-9
2-Chloroethylmethanesulfonate
Ethanol, 2-chloro-, methanesulfonate
Chloroethyl methanesulfonate
Chloroethyl methanesulphonate
Methanesulfonic acid, 2-chloroethyl ester
2-Chloroethylmethanesulfonate, puriss
NSC 18016
2-Chloroethyl methanesulphonate
beta-Chloroethylmethanesulfonate
CB 1506
EINECS 222-672-6
Methanesulfonic acid, chloroethyl ester
BRN 1754022
AI3-26395
NSC-18016
895H18Q125
DTXSID20189220
2CIEMS
DTXCID50111711
MFCD00007560
UNII-895H18Q125
chloroethyl mesylate
2-Chloroethyl mesylate
WLN: WS1&O2G
CHEMBL275438
SCHEMBL2734239
.beta.-Chloroethylmethanesulfonate
FMMYTRQXHORTCU-UHFFFAOYSA-N
NSC18016
AKOS006222794
CS-W013279
2-Chloroethyl methanesulfonate, >=99%
Methanesulfonic Acid 2-Chloroethyl Ester
BS-16652
Methanesulfonic acid 2-chloro-ethyl ester
SY051715
DB-048861
C2231
NS00029903
H11355
Q27269999