Skip to main content

Choline Chloride

ADVERTISEMENT
Identification
Molecular formula
C5H14ClNO
CAS number
67-48-1
IUPAC name
2-chloroethyl(trimethyl)ammonium;chloride
State
State
Choline chloride is typically found in a solid state at room temperature. It exists as colorless crystals that are quite hygroscopic.
Melting point (Celsius)
302.00
Melting point (Kelvin)
575.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
139.62g/mol
Molar mass
139.6230g/mol
Density
0.9702g/cm3
Appearence

Choline chloride appears as a white crystalline powder. It is highly soluble in water, and its crystal structure allows it to easily absorb moisture from the environment, leading to potential clumping if not stored properly.

Comment on solubility

Solubility of 2-chloroethyl(trimethyl)ammonium chloride

2-chloroethyl(trimethyl)ammonium chloride, a quaternary ammonium salt, exhibits notable solubility characteristics that are influenced by its chemical structure. Here are some key points regarding its solubility:

  • Water Solubility: This compound is generally highly soluble in water due to the presence of the quaternary ammonium ion, which has a +1 charge that attracts water molecules.
  • Polar Solvent Compatibility: In addition to water, it may also dissolve well in other polar solvents, such as methanol and ethanol, due to the similar polar nature of these solvents.
  • Hydrophobic Interactions: The chloroethyl group adds a hydrophobic character, which can limit its solubility in non-polar solvents, thereby enhancing its specificity for polar environments.
  • Temperature Effects: As with many ionic compounds, solubility can increase with temperature, allowing for greater dissolution in warmer conditions.

As a quaternary ammonium compound, 2-chloroethyl(trimethyl)ammonium chloride can easily interact with water, confirming its role in various aqueous applications. Understanding its solubility properties is crucial, especially in fields such as biochemistry and medicinal chemistry, where solubility often dictates the bioavailability and effectiveness of a compound.

Interesting facts

Interesting Facts about 2-Chloroethyl(trimethyl)ammonium Chloride

2-Chloroethyl(trimethyl)ammonium chloride is a fascinating compound with a variety of applications and intriguing properties. Here are some key points to consider:

  • Classified as a Quaternary Ammonium Salt: This compound consists of a central nitrogen atom bonded to three methyl groups and a chloroethyl group, along with a chloride ion. Quaternary ammonium compounds are known for their unique properties and functions in different fields.
  • Use in Pharmaceuticals: This compound is often utilized in medicinal chemistry, where it acts as an intermediate in the synthesis of various pharmaceuticals. Its ability to modify biological activity makes it an excellent candidate for drug development.
  • Role in Surfactants: Due to its amphiphilic nature, 2-chloroethyl(trimethyl)ammonium chloride is frequently used in the formulation of surfactants. These compounds reduce surface tension and help stabilize emulsions, which are essential in cosmetics and personal care products.
  • Potential Antimicrobial Properties: Some studies suggest that quaternary ammonium compounds exhibit antimicrobial activity, making them useful in disinfectants and antiseptic formulations. This adds to the compound’s relevance in public health and hygiene applications.
  • Versatile Solubility: The chloride ion contributes to the compound's solubility in polar solvents, enabling its use in various chemical processes and formulations.
  • Important in Organic Synthesis: This compound plays a critical role in organic synthesis, particularly in reactions involving nucleophilic substitutions. Chemists value it for creating complex molecules.

"The versatility of 2-chloroethyl(trimethyl)ammonium chloride exemplifies the importance of exploring and understanding quaternary ammonium compounds in modern chemistry."

In conclusion, 2-chloroethyl(trimethyl)ammonium chloride is not just an ordinary chemical; it serves as a significant pillar in the interplay between chemistry and applications in medicine, hygiene, and organic synthesis. Understanding this compound opens avenues for innovation in both research and practical applications.

Synonyms
Chlormequat chloride
999-81-5
2-Chloro-N,N,N-trimethylethanaminium chloride
Chlorocholine chloride
(2-Chloroethyl)trimethylammonium chloride
Antywylegacz
Cycogan
Cyclocel
Retacel
Stabilan
Cyocel
Cycogan extra
Choline dichloride
Barleyquat
Bettaquat
Farmacel
Halloween
Helstone
Increcel
Hyquat
Lihocin
Premix
Chlorcholine chloride
Cycocel-extra
Cycocel Extra
Arotex Extra
Barleyquat B
Chlorcholinchlorid
Bercema CCC
5C Cycocel
Hormocel-2CCC
Mirbel 5
Hico CCC
Cycocel C 5
Titan
Cycocel 460
Chlormequat chloride [ISO]
Caswell No. 191
NCI-C02960
2-Chloroethyltrimethylammonium chloride
Ethanaminium, 2-chloro-N,N,N-trimethyl-, chloride
Chlorcholinchlorid [Czech]
WR 62
CCC (plant growth regulant)
CCRIS 135
HSDB 1541
2-Chloroethyl trimethyl ammonium chloride
60-CS-16
CCC Plant growth regulant
EI 38,555
(beta-Chloroethyl)trimethylammonium chloride
EINECS 213-666-4
Ce ce ce
NSC 34858
EPA Pesticide Chemical Code 018101
UNII-PPL2215L82
(2-Chloroethyl)trimethylchloride ammonium
AC 38555
DTXSID6020303
Trimethyl-beta-Chloroethylammonium chloride
AI3-26939
PPL2215L82
Ammonium, (2-chloroethyl)trimethyl-, chloride
2-Chloraethyl-trimethylammoniumchlorid [German]
NSC-34858
Trimethyl-beta-chlorethylammoniumchlorid [Czech]
2-Chloraethyl-trimethylammoniumchlorid
2-chloro-N,N,N-trimethylethan-1-aminium chloride
Trimethyl-beta-chlorethylammoniumchlorid
Chloride, Chlormequat
2-Chloro-N,N,N-trimethylethanaminium chloride (1:1)
DTXCID20303
CHLORMEQUAT CHLORIDE [MI]
CHEBI:137392
CHLORMEQUAT CHLORIDE [HSDB]
Chlorcholinchloride
AC-38555
Trimethyl-.beta.-chlorethylammoniumchlorid
.beta.-Chloroethyltrimethylammonium chloride
Trimethyl-.beta.-chloroethylammonium chloride
CHLORCHOLINCHLORID (CZECH)
Chlorinecolinchloride
Chloride, Chlorocholine
(.beta.-Chloroethyl)trimethylammonium chloride
Cycocelextra
CeCeCe
Hormocel2CCC
MICROCIL
NEW 5C CYCOCEL
NEW'5C' CYCOCEL
2Chloraethyltrimethylammoniumchlorid
Trimethylbetachlorethylammoniumchlorid
(2Chloroethyl)trimethylammonium chloride
(2Chloroethyl)trimethylchloride ammonium
Trimethylbetachloroethylammonium chloride
USEPA/OPP Pesticide Code: 018101
(betaChloroethyl)trimethylammonium chloride
2ChloroN,N,Ntrimethylethanaminium chloride
Ammonium, (2chloroethyl)trimethyl, chloride
Ethanaminium, 2chloroN,N,Ntrimethyl, chloride
BETA-CHLOROETHYLTRIMETHYLAMMONIUM CHLORIDE
213-666-4
60cs16
un2811
Chlorocholine (chloride)
MFCD00011869
CCC
TUR
CHEMBL118539
Ammonium chloride, 2-chloroethyltrimethyl-
(2-chloroethyl)trimethylazanium chloride
2-chloroethyl(trimethyl)azanium;chloride
SCHEMBL54309
Chlormequat-chloride 100 microg/mL in Acetonitrile
HY-B1886R
Ethanaminium, 2-chloro-N,N,N-trimethyl-, chloride (1:1)
UHZZMRAGKVHANO-UHFFFAOYSA-M
HY-B1886
NSC34858
Chlorocholine (chloride) (Standard)
Tox21_200065
AKOS006222792
CS-W008900
FC33207
KS-5355
WLN: G2K1&1&1 &Q &G
NCGC00257619-01
CAS-999-81-5
SY078672
(2-Chloroethyl)-trimethylammonium chloride
2-Chloro-N,N-trimethylethanaminium chloride
DB-057817
NS00079961
EN300-2009035
Q23050130