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Bupivacaine Dichloride

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Identification
Molecular formula
C18H28Cl2N2O3
CAS number
32566-79-7
IUPAC name
(2-chlorophenyl)methyl-[2-[[4-[2-[(2-chlorophenyl)methyl-diethyl-ammonio]ethylamino]-4-oxo-butanoyl]amino]ethyl]-diethyl-ammonium;dichloride
State
State

Bupivacaine Dichloride is commonly found in a solid state at room temperature.

Melting point (Celsius)
248.00
Melting point (Kelvin)
521.15
Boiling point (Celsius)
400.00
Boiling point (Kelvin)
673.15
General information
Molecular weight
325.90g/mol
Molar mass
325.8960g/mol
Density
1.1131g/cm3
Appearence

Bupivacaine Dichloride typically appears as a white crystalline powder. It is odorless and has a bitter taste.

Comment on solubility

Solubility of (2-chlorophenyl)methyl-[2-[[4-[2-[(2-chlorophenyl)methyl-diethyl-ammonio]ethylamino]-4-oxo-butanoyl]amino]ethyl]-diethyl-ammonium;dichloride

The solubility of the compound (2-chlorophenyl)methyl-[2-[[4-[2-[(2-chlorophenyl)methyl-diethyl-ammonio]ethylamino]-4-oxo-butanoyl]amino]ethyl]-diethyl-ammonium;dichloride is influenced by several factors, particularly its ionic nature and the presence of chlorophenyl groups. Here’s what to consider:

  • Ionic Nature: As a quaternary ammonium compound, it likely exhibits high solubility in polar solvents like water.
  • Effect of Chlorine Substituents: The presence of chlorophenyl groups may lead to differential solubility behavior, often enhancing solubility in organic solvents.
  • Counter-Ion Contribution: The dichloride ion can enhance solubility, especially in aqueous solutions due to its ability to stabilize interactions.

In general, you can expect the compound to be:

  • Soluble in polar solvents (e.g., water, methanol)
  • Less soluble in non-polar solvents (e.g., hexane)

As a summary, the solubility of (2-chlorophenyl)methyl-[2-[[4-[2-[(2-chlorophenyl)methyl-diethyl-ammonio]ethylamino]-4-oxo-butanoyl]amino]ethyl]-diethyl-ammonium;dichloride displays typical characteristics of quaternary ammonium compounds, making it a fascinating subject for further study in both biomedical and chemical applications.

Interesting facts

Interesting Facts About (2-chlorophenyl)methyl-[2-[[4-[2-[(2-chlorophenyl)methyl-diethyl-ammonio]ethylamino]-4-oxo-butanoyl]amino]ethyl]-diethyl-ammonium; dichloride

This compound is a fascinating member of the class of bis-quaternary ammonium salts, revealing intriguing aspects in medicinal chemistry and therapeutic development.

Key Highlights:

  • Biological Relevance: Compounds like this often exhibit significant biological activities, such as anti-tumor, anti-microbial, or anti-viral properties. These functionalities can stem from their complex structure, which allows them to interact effectively with various biological molecules.
  • Quaternary Ammonium Structure: The presence of quaternary ammonium ions in its structure suggests potential applications in drug development, as they are known for their ability to interact with membranes, facilitating drug delivery systems.
  • Chlorine Substituents: The two chlorophenyl groups contribute to the compound's physicochemical properties, impacting its biological activity and solubility, which are essential for medicinal effectiveness.
  • Potential for Drug Resistance Studies: The complex nature of this compound makes it a valuable candidate in research focused on overcoming drug resistance mechanisms in pathogenic organisms, particularly in the realm of cancer treatment.

As the study of such compounds evolves, the intricate balance between structure and function continues to be a central theme in understanding their biological roles. As chemists delve deeper into the nuances of their mechanisms, new therapeutic potentials may emerge from the rich chemical landscapes offered by compounds like this one.

Future Perspectives:

Continued research may unlock novel uses and modifications that could improve efficacy and reduce side effects. Exploring analogues of this compound can lead to enhanced understanding and advancements in targeted therapies.

Synonyms
(Succinylbis(iminoethylene))bis((o-chlorobenzyl)diethylammonium chloride)
AMMONIUM, (SUCCINYLBIS(IMINOETHYLENE))BIS((o-CHLOROBENZYL)DIETHYL-, DICHLORIDE
15947-93-0