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2-Chloroquinoline

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Identification
Molecular formula
C9H6ClN
CAS number
612-62-4
IUPAC name
2-chloroquinoline
State
State

At room temperature, 2-Chloroquinoline is in a solid state. It is typically a crystalline solid, which means it has a well-organized, repeating structure at the microscopic level.

Melting point (Celsius)
35.00
Melting point (Kelvin)
308.15
Boiling point (Celsius)
272.00
Boiling point (Kelvin)
545.15
General information
Molecular weight
161.59g/mol
Molar mass
161.5910g/mol
Density
1.2760g/cm3
Appearence

2-Chloroquinoline appears as a yellow or light amber-colored crystalline powder. It is typically found in a solid form at room temperature and may have a slight characteristic odor. The appearance can vary slightly depending on the purity and specific form in which it is prepared.

Comment on solubility

Solubility of 2-chloroquinoline

2-chloroquinoline, with the formula C9H6ClN, presents interesting characteristics concerning its solubility. Understanding the solubility of this compound allows for a better grasp of its potential applications and behaviors in various environments.

General characteristics of its solubility include:

  • Solvent interactions: 2-chloroquinoline is known to be relatively soluble in organic solvents such as ethanol and acetone.
  • Water solubility: It has limited solubility in water, which is a common trait for many chlorinated aromatic compounds.
  • Influence of temperature: As temperature increases, the solubility in organic solvents often rises, enhancing its dissolution.

As stated, "the solubility of a compound can dictate its reactivity, mobility, and bioavailability." For 2-chloroquinoline, its moderate solubility in organic solvents makes it an excellent candidate for various chemical reactions and applications, especially in synthesis and pharmaceuticals.

In summary, while 2-chloroquinoline's solubility profile may not be extraordinarily high in water, its behavior in organic media opens doors to numerous industrial and research opportunities. Understanding these solubility properties is key to effectively utilizing this compound in practical applications.

Interesting facts

Interesting Facts about 2-Chloroquinoline

2-Chloroquinoline is a fascinating compound that belongs to the quinoline family, which is characterized by its unique aromatic structure. Here are some remarkable aspects of this compound:

  • Structural Significance: The presence of a chlorine atom at the second position of the quinoline ring significantly influences its chemical properties and reactivity, making it an important building block in organic synthesis.
  • Biological Relevance: Compounds related to 2-chloroquinoline have been studied for their potential as antimalarial agents. The transformation of quinoline derivatives into drug candidates has led to breakthroughs in treating diseases caused by Plasmodium parasites.
  • Industrial Applications: This compound is utilized in various sectors, including the production of dyes, pharmaceuticals, and agrochemicals. Its ability to act as a precursor for synthesizing more complex compounds demonstrates its versatility.
  • Environmental Concerns: Like many chlorinated compounds, 2-chloroquinoline can pose environmental risks due to its potential persistence and bioaccumulation in ecosystems. Research is ongoing to understand its effects and develop methods for remediation.
  • Research Insights: Ongoing studies on the reactivity of 2-chloroquinoline have revealed interesting aspects about electrophilic substitution reactions, expanding the toolbox for chemists working in synthetic methods.

In summary, 2-chloroquinoline is not just a simple molecule; it encapsulates vital information about its application in medicinal chemistry and its role in industrial processes. As scientists and students continue to explore its properties, 2-chloroquinoline remains a compound of significant interest in both research and practical applications.

Synonyms
2-Chloroquinoline
612-62-4
QUINOLINE, 2-CHLORO-
NSC 6163
CCRIS 3977
UX7RIN8GEW
EINECS 210-317-8
BRN 0112561
AI3-08909
NSC-6163
CHLOROQUINOLINE, 2-
DTXSID8060612
5-20-07-00312 (Beilstein Handbook Reference)
Quinoline, 2chloro
DTXCID2042985
210-317-8
2-chloro-quinoline
Chloroquinoline
MFCD00006741
NSC6163
Quinoline, chloro-
UNII-UX7RIN8GEW
chioroquinoline
2-Chloroquinoline, 99%
SCHEMBL7252
CHEMBL2042580
OFUFXTHGZWIDDB-UHFFFAOYSA-
ALBB-025860
STR07222
BBL100153
STL511939
AKOS000120670
AB00798
AC-2439
CS-W007458
FC15072
SY001152
DB-012685
EU-0033663
NS00034626
EN300-20994
AH-034/32825008
SR-01000390732
doi:10.14272/OFUFXTHGZWIDDB-UHFFFAOYSA-N.1
SR-01000390732-1
Q27291324
F0451-0421
Z104485978
InChI=1/C9H6ClN/c10-9-6-5-7-3-1-2-4-8(7)11-9/h1-6H