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2-Cyano-2-phenylacetic acid

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Identification
Molecular formula
C9H7NO2
CAS number
4226-01-5
IUPAC name
2-cyano-2-phenyl-acetic acid
State
State

At room temperature, 2-Cyano-2-phenylacetic acid is in a solid state, typically presenting as a crystalline powder.

Melting point (Celsius)
112.00
Melting point (Kelvin)
385.15
Boiling point (Celsius)
308.00
Boiling point (Kelvin)
581.15
General information
Molecular weight
161.16g/mol
Molar mass
161.1610g/mol
Density
1.2300g/cm3
Appearence

2-Cyano-2-phenylacetic acid is a white crystalline solid. Its crystals can appear as fine, needle-like structures that are uniform in shape.

Comment on solubility

Solubility of 2-cyano-2-phenyl-acetic acid

2-cyano-2-phenyl-acetic acid, with the chemical formula C10H9NO2, exhibits unique solubility characteristics that are influenced by its molecular structure.

Key Solubility Attributes:

  • Polarity: This compound contains both polar and nonpolar regions, which affects its solubility in various solvents.
  • Solvent Compatibility: It is generally soluble in polar solvents such as water and ethanol, while showing limited solubility in nonpolar solvents.
  • Influence of pH: The solubility can be affected by the pH of the solution, as the carboxylic acid group can deprotonate, increasing solubility in alkaline conditions.

To summarize, one can say:

"The solubility of 2-cyano-2-phenyl-acetic acid is ideally suited for polar environments, yet it remains significantly affected by external factors such as solvent type and pH levels."

In applications, understanding these solubility properties is crucial for optimizing the formulation and effectiveness of this compound in various chemical processes.

Interesting facts

Interesting Facts about 2-Cyano-2-phenyl-acetic Acid

2-Cyano-2-phenyl-acetic acid is a fascinating compound that boasts a unique structure and a range of interesting applications in the field of organic chemistry. Here are some noteworthy facts about this compound:

  • Historical Significance: This compound has played a crucial role in the development of various chemical syntheses, particularly in the context of pharmaceuticals.
  • Diverse Applications: 2-Cyano-2-phenyl-acetic acid is utilized in several fields including:
    • Medicinal Chemistry: serves as an important intermediate in the synthesis of various drugs.
    • Agricultural Chemistry: can be used in the formulation of specific agrochemicals.
    • Material Science: contributes to the development of novel materials with unique properties.
  • Reactivity: The compound contains a cyano group, making it susceptible to nucleophilic attack, which can lead to a variety of chemical transformations. This feature is vital in creating more complex molecules.
  • Synthetic Route: Various methods exist for synthesizing this compound, often involving the reaction of phenyl acetic acid derivatives with cyanide sources.
  • Analytical Importance: Researchers often utilize techniques such as HPLC (High-Performance Liquid Chromatography) to analyze and confirm the structure and purity of 2-cyano-2-phenyl-acetic acid.

Overall, the intriguing properties and versatility of 2-cyano-2-phenyl-acetic acid make it a significant subject of study for chemists looking to expand their understanding of organic reactions and compound synthesis.

Synonyms
2-Cyano-2-phenylacetic acid
14025-79-7
Benzeneacetic acid, alpha-cyano-
Phenylcyanoacetic acid
cyano(phenyl)acetic acid
Cyanophenylacetic acid
alpha-Cyanobenzeneacetic acid
Acetic acid, cyanophenyl-
BRN 2047564
NoName_170
ACETIC ACID, 2-CYANO-2-PHENYL-
alpha-cyanophenylacetic acid
alpha-cyano-phenylacetic acid
SCHEMBL1019171
SCHEMBL6960576
DTXSID10901110
DKFPBXQCCCIWLC-UHFFFAOYSA-N
AC8944
MFCD01672079
STK026968
AKOS004120879
AKOS022085523
SY263427
DB-063332
CS-0104536