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N-[(4-dimethylamino)phenyl]acrylamide

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Identification
Molecular formula
C12H14N2O
CAS number
16400-06-5
IUPAC name
2-cyano-3-[4-(dimethylamino)phenyl]prop-2-enamide
State
State

At room temperature, it is typically a solid. It is stable under standard room conditions, though it needs to be stored properly to avoid degradation.

Melting point (Celsius)
146.50
Melting point (Kelvin)
419.70
Boiling point (Celsius)
410.15
Boiling point (Kelvin)
683.30
General information
Molecular weight
201.25g/mol
Molar mass
201.2500g/mol
Density
1.1940g/cm3
Appearence

The compound typically appears as a yellow crystalline solid.

Comment on solubility

Solubility of 2-cyano-3-[4-(dimethylamino)phenyl]prop-2-enamide

The compound 2-cyano-3-[4-(dimethylamino)phenyl]prop-2-enamide is notable for its variable solubility profile, which can depend heavily on the conditions under which it is tested. Here are some key points regarding its solubility:

  • Solvent Dependency: This compound is generally more soluble in polar solvents due to the presence of functional groups that can form hydrogen bonds.
  • Environmental Factors: Factors such as temperature and pH can significantly influence solubility, with higher temperatures typically increasing solubility.
  • Structural Influence: The dimethylamino group enhances polarity, potentially increasing solubility in polar organic solvents.
  • Limited Water Solubility: However, its overall water solubility may be limited, making it less soluble in aqueous solutions.

In summary, while 2-cyano-3-[4-(dimethylamino)phenyl]prop-2-enamide exhibits promising solubility traits in certain solvents, its practical solubility must be evaluated under specific conditions to determine its applicability in various chemical and pharmaceutical contexts.

Interesting facts

Exploring 2-Cyano-3-[4-(dimethylamino)phenyl]prop-2-enamide

2-Cyano-3-[4-(dimethylamino)phenyl]prop-2-enamide is a fascinating chemical compound that plays a significant role in various fields, particularly in organic chemistry and pharmaceuticals. Here are some intriguing facts about this compound:

  • Structure: This compound features a unique molecular framework that includes a cyano group, an amide, and a dimethylamino group. This diverse structure allows it to participate in a wide range of chemical reactions.
  • Reactivity: The presence of the cyano and amide functional groups makes this compound quite reactive. It can undergo nucleophilic additions, facilitating the formation of more complex molecules.
  • Biological Activity: Many compounds with similar structures have been investigated for their pharmaceutical properties, potentially serving as intermediates in drug synthesis. The dimethylamino group is known to enhance solubility and biological activity.
  • Applications: Its derivatives are often explored for use in medicinal chemistry. They are connected to therapeutic agents that target various diseases, including cancer.
  • Synthetic Pathways: The synthesis of 2-cyano-3-[4-(dimethylamino)phenyl]prop-2-enamide can involve multiple methods, including the condensation of reactive precursors. This positions it as a significant compound in synthetic routes.
  • Research Potential: Due to its intriguing properties, this compound is a subject of scientific research, including studies aimed at developing new antitumor or antiviral agents.

As students and researchers delve into the realm of organic compounds, 2-cyano-3-[4-(dimethylamino)phenyl]prop-2-enamide serves as an excellent example of how structural nuances translate into significant chemical behaviors and applications. Its ability to participate in a myriad of reactions while also holding potential therapeutic benefits underscores the beauty and complexity of organic chemistry.

Synonyms
ALPHA-CYANO-4-(DIMETHYLAMINO)-CINNAMAMIDE
2-Cyano-3-[4-(dimethylamino)phenyl]-2-propenamide
2-Cyano-3-(4-(dimethylamino)phenyl)-2-propenamide
652-137-6
SCHEMBL5950171
DTXSID201233741
AKOS030690504