Norcoclaurine | Solubility of Things

Identification

Molecular formula

C₁₆H₁₇NO₃

CAS number

63110-24-7

IUPAC name

2-(cyclobutylamino)-1-(3,4-dihydroxyphenyl)ethanone

State

At room temperature, Norcoclaurine is a solid. Its crystalline nature allows it to form structured shapes when precipitated from solvents.

Melting point (Celsius)

211.00

Melting point (Kelvin)

484.15

Boiling point (Celsius)

398.15

Boiling point (Kelvin)

671.30

General information

Molecular weight

241.27g/mol

Molar mass

241.2690g/mol

Density

1.3190g/cm³

Appearence

The compound typically appears as a white to off-white crystalline powder. It may also be hygroscopic, meaning it can absorb moisture from the air, which can affect its appearance and handling.

Comment on solubility

Solubility of 2-(cyclobutylamino)-1-(3,4-dihydroxyphenyl)ethanone

The solubility of 2-(cyclobutylamino)-1-(3,4-dihydroxyphenyl)ethanone, a compound with the chemical formula C₁₆H₁₇NO₃, can be influenced by various factors including its molecular structure and the presence of functional groups. Here are some key points regarding its solubility:

Polarity: The presence of hydroxyl (-OH) groups generally increases the polarity of the molecule, which can enhance its solubility in polar solvents such as water.
Hydrogen Bonding: The hydroxyl groups are capable of forming hydrogen bonds with water, further aiding in solubility.
Aliphatic and Aromatic Structures: The cyclobutyl group and aromatic portion may induce some hydrophobic character, potentially limiting solubility in water but encouraging interaction with organic solvents.
Solvent Dependence: While solubility in water might be moderate, the compound may exhibit higher solubility in organic solvents such as ethanol or dimethyl sulfoxide (DMSO).

As with many organic compounds, the balance of polar and non-polar characteristics dictates its solubility profile. Researchers and chemists often state that, "Understanding the solubility of a compound is crucial for practical applications, including formulation and synthesis." Therefore, for 2-(cyclobutylamino)-1-(3,4-dihydroxyphenyl)ethanone, the solubility must be carefully evaluated in various solvents to ascertain its utility in diverse chemical contexts.

Interesting facts

Interesting Facts About 2-(Cyclobutylamino)-1-(3,4-dihydroxyphenyl)ethanone

This intriguing compound, known as 2-(cyclobutylamino)-1-(3,4-dihydroxyphenyl)ethanone, is notable for its complex structure and potential applications in medicinal chemistry. Below are some fascinating insights into this compound:

Structural Uniqueness: The presence of a cyclobutyl group makes this compound unique. Cyclobutyl groups contribute to interesting conformational properties due to their ring strain, which can influence the compound's reactivity and interactions.
Biological Activity: Compounds with similar structures have exhibited promising biological activities. The incorporation of a phenolic moiety—like the 3,4-dihydroxyphenyl unit—often enhances their potential as pharmaceuticals, particularly in targeting specific enzymatic pathways.
Potential Applications: Research indicates that compounds such as this one could play a role in treating various disorders, including neurological conditions and mood disorders, by influencing neurotransmitter systems.
Modification Versatility: The functional groups available in this compound provide opportunities for chemical modification, allowing for the synthesis of analogs with possibly enhanced potency or selectivity.
Research Status: While much remains to be explored, ongoing studies may reveal further insights into the mechanism of action and therapeutic potential of this compound, contributing to the ever-growing field of drug discovery.

Overall, 2-(cyclobutylamino)-1-(3,4-dihydroxyphenyl)ethanone represents an exciting subject of study in the realm of organic and medicinal chemistry, promising avenues for future research.

Synonyms

2-(cyclobutylamino)-1-(3,4-dihydroxyphenyl)ethanone