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Identification
Molecular formula
C17H23N3O2
CAS number
134659-97-1
IUPAC name
2-(cyclohexanecarbonyl)-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
State
State

At room temperature, the compound typically exists in a solid state, often as a crystalline powder or solid mass.

Melting point (Celsius)
150.00
Melting point (Kelvin)
423.15
Boiling point (Celsius)
450.00
Boiling point (Kelvin)
723.15
General information
Molecular weight
285.40g/mol
Molar mass
285.3810g/mol
Density
1.2000g/cm3
Appearence

The compound typically appears as a solid crystalline structure. Its characteristics may include being white or off-white in color, depending on the purity and presence of any impurities.

Comment on solubility

Solubility of 2-(cyclohexanecarbonyl)-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one

The compound 2-(cyclohexanecarbonyl)-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one, with the chemical formula C17H23N3O2, exhibits intriguing solubility characteristics. Understanding the solubility of this compound is critical for applications in pharmaceuticals and organic synthesis. Below are some key points regarding its solubility:

  • The presence of the pyrazino and isoquinoline functional groups suggests that the compound might exhibit varying solubility in polar and non-polar solvents.
  • Solubility in organic solvents such as dichloromethane or ethanol may be favorable due to the hydrophobic cyclohexanecarbonyl moiety.
  • However, the potential for hydrogen bonding interactions can influence its solubility behavior significantly.
  • This compound might be less soluble in water due to its larger hydrophobic regions compared to its polar sites.
  • Experimental data would be essential to confirm these predictions, as the actual solubility can vary significantly based on temperature and the specific solvent environment.

In conclusion, while the theoretical aspects give us insights into potential solubility behavior, empirical studies are crucial to establish precise solubility characteristics that are essential for effective utilization of this compound in practical applications.

Interesting facts

Interesting Facts about 2-(cyclohexanecarbonyl)-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one

This intriguing compound, known for its complex structure, belongs to the category of isoquinolinone derivatives. Here are some captivating insights:

  • Structure and Function: The molecule features a unique arrangement that includes a pyrazino ring fused to an isoquinoline framework, which may impart interesting biological activities.
  • Potential Therapeutic Applications: Compounds with similar structures have been studied for their potential in drug discovery, particularly in the fields of neurobiology and oncology. This compound could provide valuable insights into developing new therapeutic agents.
  • Versatility in Synthesis: The synthesis of such compounds often involves intricate organic reactions, showcasing the creativity and skill of chemists in designing complex molecules.
  • Relationship to Natural Products: The structural motifs found in this compound may resemble those in various natural products, suggesting potential pathways for biogenic synthesis. Studying these relationships can aid in understanding how certain compounds interact in biological systems.
  • Broader Impact: Exploring the properties and behaviors of this compound may contribute to advancements in medicinal chemistry, pharmacology, and even material science.

In summary, this compound's rich molecular architecture and potential implications signal an exciting avenue for future research and applications. As researchers continue to delve deeper, the possibilities of utilizing or modifying such compounds could lead to significant breakthroughs.

Synonyms
praziquantel
55268-74-1
Biltricide
Droncit
Pyquiton
Cesol
Embay 8440
Praziquantelum
Cysticide
Distocide
Prazinon
2-(cyclohexanecarbonyl)-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
Praziquantelum [INN-Latin]
prazicuantel
CCRIS 4114
EMBAY-8440
Praziquantel (Biltricide)
2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one
EINECS 259-559-6
MFCD00058531
NSC-757285
BRN 0761557
MLS000038419
DTXSID9021182
UNII-6490C9U457
2-(cyclohexanecarbonyl)-2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-one
4H-Pyrazino(2,1-a)isoquinolin-4-one, 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-
135526-78-2
SMR000037139
2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino(2,1-a)isoquinolin-4-one
DTXCID501182
Prasiquantel
6490C9U457
Azinox
5-24-03-00361 (Beilstein Handbook Reference)
Cutter Tape Tabs
BROADLINE COMPONENT PRAZIQUANTEL
NSC 757285
PROFENDER COMPONENT PRAZIQUANTEL
Praziquantel [USAN:USP:INN:BAN:JAN]
PRAZIQUANTEL (EMA EPAR: VETERINARY)
Praziquantelum (INN-Latin)
2-(cyclohexanecarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one
2-cyclohexanecarbonyl-1H,2H,3H,4H,6H,7H,11bH-piperazino[2,1-a]isoquinolin-4-one
PRAZIQUANTEL (MART.)
PRAZIQUANTEL [MART.]
d-Praziquantel
PRAZIQUANTEL (USP-RS)
PRAZIQUANTEL [USP-RS]
Cutter
PRAZIQUANTEL (EP MONOGRAPH)
PRAZIQUANTEL (USP IMPURITY)
PRAZIQUANTEL [EP MONOGRAPH]
PRAZIQUANTEL [USP IMPURITY]
PRAZIQUANTEL (USP MONOGRAPH)
PRAZIQUANTEL [USP MONOGRAPH]
2-cyclohexanecarbonyl-1H,2H,3H,4H,6H,7H,11bH-pyrazino[2,1-a]isoquinolin-4-one
4H-Pyrazino[2,1-a]isoquinolin-4-one, 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-
Biltricide (TN)
Praziquantel (USAN:USP:INN:BAN:JAN)
(+/-)-Praziquantel
(S)-2-(Cyclohexanecarbonyl)-2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-one
SR-01000003100
Prazitech
PraziCleanse
Bay-8440
Praziquantel (JAN/USP/INN)
Praziquantel,(S)
NCGC00016877-01
Prestwick_402
Praziquantel Tablets
CAS-55268-74-1
Praziquantel 100 microg/mL in Acetonitrile
DACTYMOR
Praziquantel Injection
Spectrum_001119
Praziquantel (Standard)
Opera_ID_378
Droncit Canine Cestocide
Droncit Feline Cestocide
Prestwick0_000260
Prestwick1_000260
Prestwick2_000260
Prestwick3_000260
Spectrum2_001288
Spectrum3_000550
Spectrum4_000482
Spectrum5_001064
PRAZIQUANTEL [MI]
PRAZIQUANTEL [INN]
PRAZIQUANTEL [JAN]
CHEMBL976
Tapeworm Dewormer for Cats
P 4668
PRAZIQUANTEL [USAN]
cid_4891
PRAZIQUANTEL [VANDF]
Lopac0_000909
Oprea1_163497
SCHEMBL44153
BSPBio_000080
BSPBio_002199
KBioGR_000963
KBioSS_001599
MLS000028528
MLS001201812
MLS001304085
MLS002548849
MLS006011880
DivK1c_000130
PRAZIQUANTEL [WHO-DD]
PRAZIQUANTEL [WHO-IP]
SPECTRUM1500494
SPBio_001295
SPBio_002299
Praziquantel-(cyclohexyl-d11)
BPBio1_000088
Durvet Feline Tape Tabsfor Cats
SCHEMBL16019896
BDBM74574
CHEBI:45267
CHEBI:91583
HMS500G12
HY-B0244R
KBio1_000130
KBio2_001599
KBio2_004167
KBio2_006735
KBio3_001699
P02BA01
PRAZIQUANTEL [GREEN BOOK]
TAPEWORM DEWORMER FOR DOGS
NINDS_000130
GLXC-26256
HMS1568D22
HMS1920J06
HMS2090J19
HMS2092A09
HMS2095D22
HMS3259K07
HMS3262F20
HMS3655O19
HMS3712D22
Pharmakon1600-01500494
PRAZIQUANTEL [ORANGE BOOK]
Praziquantel for system suitability
BCP17829
BCP28525
BCP30228
HY-B0244
Droncit 5.68% Injectible Solution
Tox21_110660
Tox21_201950
Tox21_302927
Tox21_500909
CCG-39773
NSC757285
Praziquantel, anthelminic, neurogenic
s1691
STK030186
PRAZIQUANTELUM [WHO-IP LATIN]
AKOS000541869
AKOS016398525
Tox21_110660_1
AC-8426
DB01058
FP27126
LP00909
NC00468
SB49202
SDCCGSBI-0050884.P005
2-(Cyclohexylcarbonyl)-1,2,3,6,7-11b-hexahydro-4H-pyrazinoe(2,1a)isoquinolin-4-one
IDI1_000130
NCGC00015818-04
NCGC00015818-05
NCGC00015818-06
NCGC00015818-07
NCGC00015818-08
NCGC00015818-11
NCGC00015818-12
NCGC00015818-14
NCGC00015818-15
NCGC00015818-26
NCGC00089733-02
NCGC00089733-03
NCGC00089733-04
NCGC00089733-05
NCGC00256422-01
NCGC00259499-01
NCGC00261594-01
AS-12459
PRAZIQUANTEL COMPONENT OF BROADLINE
PRAZIQUANTEL COMPONENT OF PROFENDER
SY052322
SBI-0050884.P004
DB-052707
(S)-Praziquantel; Praziquantel, (S)-Isomer
AB00052075
EU-0100909
NS00010534
P2125
SW196645-3
1H-pyrazino[2,1-a]isoquinolin-4(11bH)-one
Worm and Parasites Aquarium Cure Program Salt
2-(cyclohexanecarbonyl)-2,3,6,7-tetrahydro-
C07367
D00471
EN300-123768
Worm and Parasites Aquarium Cure Program Fresh
AB00052075-13
AB00052075-15
AB00052075_16
AB00052075_17
Praziquantel, VETRANAL(TM), analytical standard
Q424145
Prazi-C Tablets (OTC), Praziquantel Tablets (Rx)
SR-01000003100-3
SR-01000003100-5
SR-01000003100-7
BRD-A21858158-001-05-2
BRD-A21858158-001-16-9
BRD-A21858158-001-22-7
BRD-A21858158-001-23-5
SR-01000003100-16
F0037-0136
Z1554103331
Praziquantel, European Pharmacopoeia (EP) Reference Standard
Praziquantel, United States Pharmacopeia (USP) Reference Standard
2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro- 4H-pyrazino[2,1-a]-isoquinolin-4-one
2-(Cyclohexylcarbonyl)-1,2,3,6,7-11b-hexahydro-4H-pyrazino[2,1-aisoquinolin-4-one
2-[cyclohexyl(oxo)methyl]-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
2-Cyclohexylcarbonyl-1,2,3,6,7,11b-hexahydro-4H-pyrazino(2,1-a)isoquinolin-4-one
Praziquantel for system suitability, European Pharmacopoeia (EP) Reference Standard
Praziquantel, Pharmaceutical Secondary Standard; Certified Reference Material
2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one;(+/-)-Praziquantel;Azinox
259-559-6
Droncit Canine Cestocide Tablets, Droncit Feline Cestocide Tablets, Praziquantel 34 (Rx), Tapeworm Dewormer for Cats (OTC), Tapeworm Dewormer for Dogs (OTC)
InChI=1/C19H24N2O2/c22-18-13-20(19(23)15-7-2-1-3-8-15)12-17-16-9-5-4-6-14(16)10-11-21(17)18/h4-6,9,15,17H,1-3,7-8,10-13H