Skip to main content

Carbidopa

ADVERTISEMENT
Identification
Molecular formula
C10H14N2O4
CAS number
28860-95-9
IUPAC name
2-(cyclohexylamino)-1-(3,4-dihydroxyphenyl)ethanone
State
State

Carbidopa is in a solid state at room temperature. It is a crystalline powder, suggesting a high level of purity and consistent physical properties.

Melting point (Celsius)
203.00
Melting point (Kelvin)
476.00
Boiling point (Celsius)
275.00
Boiling point (Kelvin)
548.00
General information
Molecular weight
226.24g/mol
Molar mass
226.2580g/mol
Density
1.2901g/cm3
Appearence

Carbidopa typically appears as a white to creamy-white crystalline powder. It is visibly solid and is often used in its anhydrous form or as a hydrate.

Comment on solubility

Solubility of 2-(cyclohexylamino)-1-(3,4-dihydroxyphenyl)ethanone

The solubility of 2-(cyclohexylamino)-1-(3,4-dihydroxyphenyl)ethanone in various solvents is a topic of interest for researchers and chemists alike. Several factors can influence its solubility:

  • Polarity: This compound contains both polar and nonpolar functional groups. The presence of hydroxyl groups makes it more soluble in polar solvents such as water.
  • Hydrogen Bonding: The ability to form hydrogen bonds with solvent molecules significantly increases its solubility. This is particularly relevant in aqueous solutions due to the hydroxyl groups.
  • Temperature: As with many organic compounds, the solubility can also depend on temperature. Generally, higher temperatures enhance solubility in both polar and nonpolar solvents.
  • pH Levels: The compound may exhibit varying solubility in different pH environments, particularly due to the amine group which can be protonated in acidic conditions, influencing its interactions with solvent molecules.

In practical terms, it is likely to be soluble in:

  • Water
  • Ethanol
  • Dimethyl sulfoxide (DMSO)

However, solubility may be limited in nonpolar solvents like hexane or benzene. As a quote often resonates in chemistry, "Like dissolves like," meaning that compounds will often dissolve best in solvents with similar polarity. Understanding and manipulating these solubility factors can greatly enhance the utilization of 2-(cyclohexylamino)-1-(3,4-dihydroxyphenyl)ethanone in various applications.

Interesting facts

Interesting Facts about 2-(cyclohexylamino)-1-(3,4-dihydroxyphenyl)ethanone

2-(cyclohexylamino)-1-(3,4-dihydroxyphenyl)ethanone, often referred to in short as CHDPE, is a fascinating compound that has garnered attention for its intriguing properties and potential applications. Here are some unique insights into this compound:

  • Structural Diversity: The presence of a cyclohexylamine group combined with a 3,4-dihydroxyphenyl moiety creates a unique scaffold that enables diverse interactions at the molecular level.
  • Pharmacological Potential: Compounds with similar structures have been studied for their biological activities, including antioxidant and anti-inflammatory properties, making CHDPE a candidate for further pharmaceutical exploration.
  • Research Applications: Scientists have noted that compounds like CHDPE could play an essential role in the development of new therapies, particularly in neurological disorders, due to their ability to cross the blood-brain barrier.
  • Chemical Reactivity: The ketone functional group present in CHDPE is a site of reactivity, which can be utilized in various organic synthesis reactions, paving the way for generating more complex molecular architectures.
  • In Silico Studies: Molecular modeling and docking studies on CHDPE have provided insights into its potential interactions with target proteins, aiding in the drug design process.
  • Natural Compound Relationship: Interestingly, structures similar to CHDPE have been observed in certain natural products, suggesting a potential link to biologically active substances found in plants.

In summary, 2-(cyclohexylamino)-1-(3,4-dihydroxyphenyl)ethanone is not only a compound of chemical interest but also a promising candidate for various applications in medicinal chemistry. Ongoing research continues to unveil the depths of its capabilities, making it a significant point of study for chemists and researchers alike.

Synonyms
2-(cyclohexylamino)-1-(3,4-dihydroxyphenyl)ethanone
CBDivE_016315
MLS-0315679.0001
2-(cyclohexylamino)-1-(3,4-dihydroxyphenyl)ethanone;hydrochloride
CHEMBL528918
SCHEMBL10071705
BDBM46042
cid_2841226
HMS1607H17
STK550314
AKOS001482481
CCG-103370
EU-0033687
ST50977325
AG-205/12760849
1-(3,4-dihydroxyphenyl)-2-(cyclohexylamino)ethan-1-one
2-(CYCLOHEXYLAMINO)-1-(3,4-DIHYDROXYPHENYL)ETHAN-1-ONE
1-[3,4-bis(oxidanyl)phenyl]-2-(cyclohexylamino)ethanone;hydrochloride