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Tramadol

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Identification
Molecular formula
C16H25NO
CAS number
27203-92-5
IUPAC name
2-(cyclohexylamino)-1-phenyl-ethanol
State
State

At room temperature, tramadol is a solid, specifically a white crystalline powder. It is often processed into a more usable form, such as tablets or capsules, for pharmaceutical use.

Melting point (Celsius)
179.00
Melting point (Kelvin)
452.15
Boiling point (Celsius)
313.00
Boiling point (Kelvin)
586.15
General information
Molecular weight
263.38g/mol
Molar mass
263.3840g/mol
Density
1.1970g/cm3
Appearence

Tramadol appears as a white crystalline powder. It is often found in the form of tablets or capsules when used as a medication.

Comment on solubility

Solubility of 2-(cyclohexylamino)-1-phenyl-ethanol

The solubility of 2-(cyclohexylamino)-1-phenyl-ethanol is a topic of interest due to its unique structure and functional groups. Understanding its solubility can be beneficial for various applications in organic chemistry and pharmaceuticals.

Generally, factors that influence the solubility of this compound include:

  • Polarity: The presence of the cyclohexylamine and hydroxyl groups contributes to the overall polarity of the molecule, potentially enhancing its solubility in polar solvents.
  • Hydrogen Bonding: The -OH group allows for hydrogen bonding with water and other polar solvents, which often increases solubility.
  • Molecular Size: The larger cyclohexyl group may hinder solubility in highly polar solvents due to steric hindrance, which can impact the extent to which it can interact with solvent molecules.

In essence, while 2-(cyclohexylamino)-1-phenyl-ethanol exhibits solubility in polar solvents such as water, its solubility may not be as high as that of smaller, more polar organic compounds. Understanding these nuances is crucial for optimal application within chemical processes and formulations.

Interesting facts

Interesting Facts about 2-(Cyclohexylamino)-1-phenyl-ethanol

2-(Cyclohexylamino)-1-phenyl-ethanol is a fascinating compound with a variety of applications and properties that make it noteworthy in the field of chemistry. Here are some compelling insights:

  • Pharmaceutical Relevance: This compound is often studied for its potential use in pharmaceutical developments. It exhibits properties that make it a candidate for various therapeutic applications, particularly in the field of neurochemistry.
  • Structure and Function: The presence of both the cyclohexylamino group and the phenyl group in the structure suggests a unique interaction with biological receptors, which could lead to innovative drug designs aimed at treating neurological disorders.
  • Chirality: This compound can exist as chiral forms, which means it can have different effects in biological systems. The distinction between these enantiomers can be crucial, as one may exhibit desired therapeutic effects while the other could be inert or even harmful.
  • Synthesis Routes: The synthesis of 2-(cyclohexylamino)-1-phenyl-ethanol can be achieved through various chemical reactions, including reductions and substitutions. Researchers often explore multiple synthetic pathways to optimize yields and purity.
  • Research Applications: Beyond pharmaceutical avenues, this compound is also significant in academic research. Scientists investigate its properties in organic synthesis, medicinal chemistry, and even materials science, showcasing its versatility.

In summary, 2-(cyclohexylamino)-1-phenyl-ethanol is more than just a compound with a complex structure; it represents a bridge between organic chemistry and pharmacology, with ongoing research continually uncovering its potential.

Synonyms
2-Cyclohexylamino-1-phenylethanol
6589-48-6
2-(cyclohexylamino)-1-phenylethanol
Ethanol, 2-cyclohexylamino-1-phenyl-
2-(cyclohexylamino)-1-phenylethan-1-ol
Benzenemethanol, .alpha.-[(cyclohexylamino)methyl]-
Benzyl alcohol, .alpha.-[(cyclohexylamino)methyl]-
EINECS 229-523-4
Benzyl alcohol, .alpha.-((cyclohexylamino)methyl)-
MFCD00021321
NSC 62916
BRN 0979544
Benzenemethanol, alpha-((cyclohexylamino)methyl)-
NSC62916
BENZYL ALCOHOL, alpha-(CYCLOHEXYLAMINO)METHYL-
WLN: L6TJ AM1YQR
NCIOpen2_003323
Oprea1_792848
4-13-00-01815 (Beilstein Handbook Reference)
MLS000108423
CHEMBL1900843
SCHEMBL10877574
DTXSID501265137
HMS2176N19
NSC-62916
STK031122
AKOS005381380
NCGC00076552-02
SMR000104380
DB-020989
Benzenemethanol,a-[(cyclohexylamino)methyl]-
CS-0358827
NS00046989
I+/--[(Cyclohexylamino)methyl]benzenemethanol