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2-(cyclohexylamino)ethanol

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Identification
Molecular formula
C8H17NO
CAS number
2026-48-4
IUPAC name
2-(cyclohexylamino)ethanol
State
State

At room temperature, 2-(cyclohexylamino)ethanol is primarily found in a liquid state, making it advantageous for various applications in reactions and formulations where liquid reagents are preferred.

Melting point (Celsius)
17.50
Melting point (Kelvin)
290.65
Boiling point (Celsius)
221.00
Boiling point (Kelvin)
494.15
General information
Molecular weight
129.20g/mol
Molar mass
129.1960g/mol
Density
0.9929g/cm3
Appearence

2-(Cyclohexylamino)ethanol is typically a clear, colorless liquid. The compound may appear slightly viscous and has a noticeable amine-like odor due to the amino group within its structure.

Comment on solubility

Solubility of 2-(cyclohexylamino)ethanol

2-(cyclohexylamino)ethanol, often referred to in scientific literature, exhibits interesting solubility properties that are worth noting. Its solubility can be influenced by several factors, including structure and molecular interactions.

Factors Affecting Solubility:

  • Polarity: The presence of the amino group (-NH2) contributes to the molecule's overall polarity, enhancing hydrogen bonding capabilities.
  • Hydrophobic Structure: The cyclohexyl group provides a hydrophobic nature, which can reduce solubility in polar solvents like water.
  • Solvent Type: It is generally more soluble in organic solvents, such as ethanol or dichloromethane, due to favorable interactions with similar non-polar or less polar solvents.

Therefore, one could observe the following:
While 2-(cyclohexylamino)ethanol displays moderate solubility in water, it typically shows enhanced solubility in non-polar organic solvents. This behavior is crucial for applications in chemical synthesis and pharmaceuticals, as the solubility profile determines the feasibility of usage in various reaction conditions.

Practical Implications:

  • In biological systems, solubility can affect bioavailability and transport mechanisms.
  • In synthetic processes, understanding solubility allows for optimal reaction conditions.

Overall, the solubility of 2-(cyclohexylamino)ethanol is a pivotal characteristic that influences its utility across different applications.

Interesting facts

Interesting Facts about 2-(Cyclohexylamino)ethanol

2-(Cyclohexylamino)ethanol is a fascinating compound that plays an important role in various chemical and pharmaceutical applications. Here are some intriguing insights about this compound:

  • Structural Significance: The presence of a cyclohexyl group in its structure imparts unique steric and electronic properties, making it an interesting subject of study for chemists interested in molecular interactions.
  • Biological Activity: This compound has demonstrated potential in medicinal chemistry as a building block for developing pharmaceutical agents, particularly in the treatment of neurological and depression-related conditions.
  • Synthesis Applications: 2-(Cyclohexylamino)ethanol can be synthesized through various organic reactions, allowing researchers to explore synthetic pathways that can lead to diverse derivatives with tailored functionalities.
  • Hydrogen Bonding: The hydroxyl (-OH) group in 2-(cyclohexylamino)ethanol allows it to engage in hydrogen bonding, which can affect its solubility and interaction with other molecules, making it an important factor in biochemical systems.
  • Research Potential: Ongoing research is examining its effects on cellular pathways, indicating that this compound could be a promising candidate for further investigation in pharmacological studies.

Overall, 2-(cyclohexylamino)ethanol exemplifies the rich intersection of organic chemistry and medicinal research, underscoring the compound's importance in the ongoing quest for novel therapeutic agents.

Synonyms
2842-38-8
2-(CYCLOHEXYLAMINO)ETHANOL
Ethanol, 2-(cyclohexylamino)-
Abbomeen E-25 aerosol
2-Cyclohexylaminoethanol
Cyclohexlaminoethanol
Abromeen E-25
N-(2-Hydroxyethyl)cyclohexylamine
Cyclohexylamine, hydroxyethyl-
N-Hydroxyethylcyclohexylamine
N-(2-Hydroxyethyl) cyclohexylamine
NSC 1505
N-(Cyclohexylamino)ethanol (VAN)
Ethanol, 2-(cyclohexylamino)-, (aerosol)
EINECS 220-636-4
BRN 1071413
N-(Cyclohexylamino)ethanol
MGUMZJAQENFQKN-UHFFFAOYSA-
DTXSID00182633
DTXCID40105124
220-636-4
inchi=1/c8h17no/c10-7-6-9-8-4-2-1-3-5-8/h8-10h,1-7h2
N-Cyclohexylethanolamine
2-(cyclohexylamino)ethan-1-ol
N-Cyclohexylaminoethanol
NSC-1505
F723W4Z785
Ethanol, (aerosol)
MFCD00021326
WLN: L6TJ AM2Q
Ethanol,2-(cyclohexylamino)-
SCHEMBL131659
CHEMBL4528441
N-Cyclohexyl-2-hydroxyethylamine
UNII-F723W4Z785
NSC1505
ALBB-026139
N-(2-Hydroxyethyl)-N-cyclohexylamine
N-cyclohexyl-N-(2-hydroxyethyl)amine
AKOS000121422
GS-5424
SB83853
BP-10467
DB-244277
C1082
NS00028483
EN300-18800
D95373
Z90504557
F2190-0353