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Carbidopa

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Identification
Molecular formula
C10H14N2O4
CAS number
28860-95-9
IUPAC name
2-(cyclopentylamino)-1-(3,4-dihydroxyphenyl)ethanone
State
State

Carbidopa is a solid at room temperature.

Melting point (Celsius)
205.50
Melting point (Kelvin)
478.65
Boiling point (Celsius)
459.00
Boiling point (Kelvin)
732.15
General information
Molecular weight
226.24g/mol
Molar mass
226.2590g/mol
Density
1.6025g/cm3
Appearence

Carbidopa is typically a white to slightly yellow crystalline powder. It is slightly soluble in water and practically insoluble in alcohol and organic solvents.

Comment on solubility

Solubility of 2-(cyclopentylamino)-1-(3,4-dihydroxyphenyl)ethanone

The solubility of 2-(cyclopentylamino)-1-(3,4-dihydroxyphenyl)ethanone can be influenced by several factors due to its unique chemical structure. Generally, its solubility properties can be categorized as follows:

  • Polarity: The presence of hydroxyl (-OH) groups in the compound enhances its polarity, which often increases solubility in polar solvents such as water.
  • Hydrophobic Effects: The cyclopentyl group contributes to the hydrophobic character, which may limit solubility in highly polar solvents.
  • Temperature Dependence: Solubility is typically temperature-dependent; hence, higher temperatures may improve solubility in solvents.
  • pH Influence: Because of the amine functional group, the solubility may vary with pH, making the compound more soluble in acidic conditions due to protonation.

In summary, the solubility of 2-(cyclopentylamino)-1-(3,4-dihydroxyphenyl)ethanone is likely to be variable, characterized by its:

  • Increased solubility in polar solvents,
  • Potential limitations in hydrophobic environments, and
  • Sensitivity to temperature and pH changes.

Understanding these factors is crucial for predicting the behavior of this compound in various chemical and biological systems.

Interesting facts

Interesting Facts About 2-(cyclopentylamino)-1-(3,4-dihydroxyphenyl)ethanone

2-(cyclopentylamino)-1-(3,4-dihydroxyphenyl)ethanone, often referred to in scientific literature and research, is an intriguing compound due to its structural complexity and potential biological activities. Here are some noteworthy aspects:

  • Structural Highlights: The compound exhibits a unique combination of a cyclopentyl group and a 3,4-dihydroxyphenyl moiety, which contributes to its distinctive chemical properties. The presence of both an amine and ketone functional group points towards interesting reactivity and interaction capabilities with different biological systems.
  • Biological Relevance: Compounds similar to this one have been studied for their potential applications in medicinal chemistry. For instance, the hydroxyl groups in the aromatic ring are often associated with increased activity in pharmacological contexts, suggesting that they may play a role in the compound's efficacy as a therapeutic agent.
  • Complexity in Synthesis: The synthesis of this compound can pose challenges due to the necessity of carefully controlling reaction conditions to achieve the desired substitution patterns and avoid forming side products. Chemists often leverage various techniques such as coupling reactions and functional group transformations to synthesize such complex molecules.
  • Research Insights: Studies involving 2-(cyclopentylamino)-1-(3,4-dihydroxyphenyl)ethanone may reveal insights into its interaction with specific biological targets, paving the way for novel therapeutic strategies. The investigational work could also shed light on how such compounds function at the molecular level, enhancing the understanding of structure-activity relationships.
  • Future Directions: The exploration of similar compounds could lead to the development of new class drugs or agents with improved efficacy and safety profiles. Ongoing research in this area continues to hold promise for advancements in medicinal chemistry.

In summary, 2-(cyclopentylamino)-1-(3,4-dihydroxyphenyl)ethanone serves as a fascinating compound within the field of chemistry, offering various pathways for exploration and discovery. Its unique structural features and potential biological applications make it a subject of continued interest for researchers and chemists alike.

Synonyms
2-(cyclopentylamino)-1-(3,4-dihydroxyphenyl)ethanone
SCHEMBL9768072