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2-cyclopropyl-2-hydroxy-2-phenylacetic acid

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Identification
Molecular formula
C11H12O3
CAS number
15879-61-3
IUPAC name
2-cyclopropyl-2-hydroxy-2-phenyl-acetic acid
State
State

At room temperature, 2-cyclopropyl-2-hydroxy-2-phenylacetic acid is typically a solid. It maintains its solid state under standard conditions (25 °C, 1 atm).

Melting point (Celsius)
129.00
Melting point (Kelvin)
402.15
Boiling point (Celsius)
305.00
Boiling point (Kelvin)
578.15
General information
Molecular weight
192.21g/mol
Molar mass
192.2120g/mol
Density
1.3229g/cm3
Appearence

2-Cyclopropyl-2-hydroxy-2-phenylacetic acid typically appears as a white to off-white crystalline powder. It is characterized by its crystalline texture and may vary slightly in appearance depending on the purity and specific form it is in.

Comment on solubility

Solubility of 2-cyclopropyl-2-hydroxy-2-phenyl-acetic acid

2-cyclopropyl-2-hydroxy-2-phenyl-acetic acid, with its unique molecular structure, exhibits certain characteristics regarding its solubility. In general, the solubility of this compound can be influenced by several factors:

  • Polarity: As a hydroxyl-functionalized compound, it tends to be more polar, which can enhance its solubility in polar solvents like water.
  • Hydrogen Bonding: The presence of the hydroxyl group allows for potential hydrogen bonding with solvents, further impacting solubility.
  • Temperature: Like many organic compounds, solubility may increase at elevated temperatures due to enhanced molecular interactions.
  • pH Levels: The ionization of the acid group can affect solubility; in a more alkaline environment, the compound may become more soluble.

In many cases, compounds with similar structures tend to show varying degrees of solubility in organic solvents such as ethanol or dimethyl sulfoxide (DMSO) due to their ability to dissolve nonpolar portions of the molecule. This compound is likely to exhibit moderate solubility in common organic solvents while maintaining reasonable solubility in water.

In summary, the solubility of 2-cyclopropyl-2-hydroxy-2-phenyl-acetic acid is a nuanced characteristic that can vary significantly based on several factors including polarity, temperature, and the chemical environment.

Interesting facts

Interesting Facts about 2-Cyclopropyl-2-hydroxy-2-phenyl-acetic Acid

2-Cyclopropyl-2-hydroxy-2-phenyl-acetic acid is a fascinating compound that combines intriguing structural features with potential biological activities. Here are some notable points:

  • Unique Structure: This compound features a cyclopropyl group which introduces strain and unique properties in its chemistry. Cyclopropyl rings often influence the reactivity and interactions with enzymes or receptors, making them of great interest in medicinal chemistry.
  • Biological Activity: Compounds that contain both hydroxyl and carboxylic acid functional groups are often associated with significant biological activities. This particular compound is considered for its potential uses in pharmaceuticals, especially due to its structural resemblance to known drug molecules.
  • Pharmacological Potential: Researchers are exploring the compound for anti-inflammatory and analgesic properties. The molecule’s ability to interact with biological targets can lead to the development of new therapeutic agents.
  • Synthesis Challenges: The synthesis of this compound may involve intricate multi-step procedures due to the presence of the cyclopropyl group, which often requires careful handling during reactions.
  • Research Interest: The compound is a subject of ongoing studies, as scientists seek to understand its mechanistic pathways and optimize its effectiveness in pharmaceutical applications. Its complexity may lead to exciting discoveries in medicinal chemistry.

By delving into the chemistry of 2-cyclopropyl-2-hydroxy-2-phenyl-acetic acid, we can unlock new possibilities for innovative drugs and enhance our understanding of how structural modifications can alter the biological profile of organic compounds.

Synonyms
1460-46-4
2-cyclopropyl-2-hydroxy-2-phenylacetic acid
alpha-Cyclopropylmandelic acid
alpha-Cyclopropyl-alpha-hydroxybenzeneacetic acid
Cyclopropylphenyl glycollic acid
MANDELIC ACID, alpha-CYCLOPROPYL-
BRN 2099019
SCHEMBL2764040
DTXSID10932747
cyclopropyl(hydroxy)phenylacetic acid