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2-decoxy-N-(2-pyrrolidin-1-ylethyl)benzamide

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Identification
Molecular formula
C23H34N2O2
CAS number
104375-20-0
IUPAC name
2-decoxy-N-(2-pyrrolidin-1-ylethyl)benzamide
State
State

In its pure form, 2-decoxy-N-(2-pyrrolidin-1-ylethyl)benzamide exists as a crystalline solid at room temperature that may melt into a liquid depending on temperature conditions. It is stable under standard conditions of temperature and pressure.

Melting point (Celsius)
60.00
Melting point (Kelvin)
333.15
Boiling point (Celsius)
403.30
Boiling point (Kelvin)
676.45
General information
Molecular weight
360.55g/mol
Molar mass
360.5540g/mol
Density
1.0500g/cm3
Appearence

2-Decoxy-N-(2-pyrrolidin-1-ylethyl)benzamide is generally a colorless to yellowish liquid or solid product, depending on the conditions of storage. Its appearance can vary with purity and method of crystallization, and it does not have a characteristic odor.

Comment on solubility

Solubility of 2-decoxy-N-(2-pyrrolidin-1-ylethyl)benzamide

The solubility of 2-decoxy-N-(2-pyrrolidin-1-ylethyl)benzamide is a topic of considerable interest due to its implications in medicinal chemistry and formulation science. While the specific solubility parameters can vary based on several factors, we can assess the behavior of this compound in various solvents.

Key Factors Affecting Solubility

  • Molecular Structure: The presence of functional groups such as the benzamide moiety and the alkoxy side chain can significantly influence hydrophilicity and lipophilicity.
  • Temperature: As with many organic compounds, increasing temperature typically enhances solubility, allowing for better dissolution of the compound in solvents.
  • pH of the Solution: Since benzamides can exhibit different ionization states in acidic or basic conditions, the pH can impact the solubility considerably.

It is often observed that compounds similar to 2-decoxy-N-(2-pyrrolidin-1-ylethyl)benzamide demonstrate variable solubility in:

  • Organic solvents (e.g., ethanol, DMSO)
  • Aqueous solutions under specific conditions

In practice, one might summarize the solubility behavior with the notion that:

"Solubility is not just a property, but a complex interplay of molecular characteristics and environmental conditions."

To optimize solubility for practical applications, it is advisable to conduct empirical solubility tests in various solvents, taking into account the aforementioned factors.

Interesting facts

Interesting Facts About 2-decoxy-N-(2-pyrrolidin-1-ylethyl)benzamide

The compound 2-decoxy-N-(2-pyrrolidin-1-ylethyl)benzamide belongs to a fascinating category of chemical compounds known for their diverse applications in medicinal chemistry. Here are some intriguing insights:

  • Structural Significance: This compound features a unique combination of functional groups, including a benzamide moiety and a pyrrolidine alkyl chain, which contribute to its biological activity. The structural complexity often correlates with versatility in biological interactions.
  • Pharmacological Potential: Compounds like this one may exhibit a range of pharmacological activities, making them attractive for drug development. The presence of the pyrrolidine ring, for example, is commonly associated with neuroactive properties, which can lead to potential therapeutic applications in areas like pain management or mental health.
  • Drug Design: The incorporation of the decoxy group and the structural arrangement allows researchers to fine-tune the compound’s reactivity and selectivity, facilitating the design of targeted therapies. This plays a crucial role in the modern approach to drug discovery.
  • Research Relevance: The investigation of such compounds is significant in the field of synthetic organic chemistry and pharmacology. Scientists often analyze how modifications in the structure can lead to enhanced efficacy or reduced side effects, highlighting the importance of structure-activity relationships (SAR).
  • Interdisciplinary Impact: Beyond chemistry, the potential implications of 2-decoxy-N-(2-pyrrolidin-1-ylethyl)benzamide extend into fields such as biochemistry, pharmacology, and even materials science, showcasing the interconnected nature of scientific research.

In conclusion, 2-decoxy-N-(2-pyrrolidin-1-ylethyl)benzamide represents a compelling example of how intricate chemical structures can lead to significant advancements in various scientific disciplines, providing a platform for future studies and innovative therapies.

Synonyms
10261-50-4
Hg-1588
BENZAMIDE, 2-DECYLOXY-N-(2-(PYRROLIDINYL)ETHYL)-
VQ3WQL0XE6
2-Decyloxy-N-(2-(pyrrolidinyl)ethyl)benzamide
NSC-78885
Benzamide, o-(decyloxy)-N-(2-(1-pyrrolidinyl)ethyl)-
2-(Decyloxy)-N-(2-(1-pyrrolidinyl)ethyl)benzamide
Benzamide, o-(decyloxy)-N-[2-(1-pyrrolidinyl)ethyl]-
2-Decyloxy-N-[2-(pyrrolidinyl)ethyl]benzamide
Benzamide, 2-decyloxy-N-[2-(pyrrolidinyl)ethyl]-
NSC 78885
NSC78885
UNII-VQ3WQL0XE6
DTXSID50145354
WLN: T5NTJ A2MVR BO10
2-(Decyloxy)-N-(2-(pyrrolidin-1-yl)ethyl)benzamide
BENZAMIDE, 2-(DECYLOXY)-N-(2-(1-PYRROLIDINYL)ETHYL)-