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2-(dibutylamino)acetohydrazide

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Identification
Molecular formula
C10H23N3O
CAS number
14204-96-3
IUPAC name
2-(dibutylamino)acetohydrazide
State
State

At room temperature, 2-(dibutylamino)acetohydrazide exists in a liquid state. It is typically handled in this form in laboratories and industry settings.

Melting point (Celsius)
-20.00
Melting point (Kelvin)
253.15
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.15
General information
Molecular weight
201.32g/mol
Molar mass
201.3160g/mol
Density
0.9000g/cm3
Appearence

2-(dibutylamino)acetohydrazide is typically a clear colorless liquid that can be slightly yellowish. It has a distinctive chemical odor which is common among amine compounds.

Comment on solubility

Solubility of 2-(dibutylamino)acetohydrazide

The solubility of 2-(dibutylamino)acetohydrazide in various solvents can greatly influence its application in different chemical processes. Here are some important points to consider regarding its solubility:

  • Polarity: This compound is likely to exhibit moderate polarity due to the presence of both hydrophobic (dibutylamino) and hydrophilic (acetohydrazide) groups.
  • Solvent Compatibility: It may dissolve well in organic solvents such as ethanol, methanol, or chloroform, but its solubility in water could be limited due to the hydrophobic nature of the dibutyl groups.
  • Temperature Influence: The solubility can also be affected by temperature; generally, increasing the temperature enhances solubility in many solvents.
  • pH Sensitivity: The solubility might vary with the pH of the solution, especially due to the presence of functional groups that can become protonated or deprotonated.

In summary, understanding the solubility characteristics of 2-(dibutylamino)acetohydrazide is crucial for its effective use in synthesis and formulation. As with many organic compounds, it is often advisable to conduct specific solubility tests to determine the optimal conditions for its use.

Interesting facts

Interesting Facts about 2-(Dibutylamino)acetohydrazide

2-(Dibutylamino)acetohydrazide is a fascinating compound that belongs to the class of hydrazides, known for their diverse applications in pharmaceuticals and agrochemicals. Here are some engaging facts about this compound:

  • Versatility in Applications: This compound's structure enables it to serve as a key intermediate in the synthesis of various bioactive molecules and pharmaceuticals, showcasing its importance in medicinal chemistry.
  • Biological Activity: Compounds containing hydrazide moieties have often been investigated for their potential antimicrobial and antitumor properties, highlighting a promising area for future research.
  • Synthetic Pathways: The synthesis of 2-(dibutylamino)acetohydrazide can be achieved through a variety of methods. Chemists often utilize reactions between hydrazine derivatives and carbonyl compounds, which demonstrates the compound's adaptability in synthetic chemistry.
  • Structure-Activity Relationship (SAR): The detailed examination of the compound's structure can provide insights into how slight modifications can affect its biological activity, making it a point of interest for structure-activity relationship studies.
  • Safety Precautions: Like many organic compounds, handling 2-(dibutylamino)acetohydrazide requires caution. Appropriate personal protective equipment should always be employed during its handling in the laboratory.

Overall, 2-(dibutylamino)acetohydrazide stands out not only for its utility in synthetic applications but also for its role in advanced research avenues in chemistry and pharmacology. It exemplifies the continued exploration of compounds that bridge the gap between organic synthesis and biological function.

Synonyms
N,N-Dibutylglycine hydrazide
GLYCINE, N,N-DIBUTYL-, HYDRAZIDE
2644-36-2
BRN 1101114
DTXSID90181034
DTXCID00103525
AKOS012880572