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2-(Dibutylamino)ethyl 4-fluorobenzoate

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Identification
Molecular formula
C17H26FNO2
CAS number
128963-65-9
IUPAC name
2-(dibutylamino)ethyl 4-fluorobenzoate
State
State

This compound is a liquid at room temperature and demonstrates typical behavior as expected from an organic ester with potential for slight viscosity.

Melting point (Celsius)
-20.00
Melting point (Kelvin)
253.20
Boiling point (Celsius)
315.60
Boiling point (Kelvin)
588.80
General information
Molecular weight
293.39g/mol
Molar mass
293.3880g/mol
Density
0.9945g/cm3
Appearence

2-(Dibutylamino)ethyl 4-fluorobenzoate generally appears as a colorless or light yellow liquid. Its physical state may exhibit slight nuances in color depending on the purity and specific preparation methods used.

Comment on solubility

Solubility of 2-(dibutylamino)ethyl 4-fluorobenzoate

The solubility of 2-(dibutylamino)ethyl 4-fluorobenzoate can be described as quite interesting due to its unique structural features. This compound presents a distinct mixture of hydrophobic and hydrophilic components, impacting its solubility in various solvents.

Factors Influencing Solubility:

  • Polar vs. Nonpolar Solvents: Due to its dibutylamino group, which is relatively bulky and nonpolar, 2-(dibutylamino)ethyl 4-fluorobenzoate tends to exhibit higher solubility in nonpolar organic solvents such as hexane and chloroform.
  • Temperature: Like many organic compounds, solubility will generally increase with an increase in temperature, allowing more of the compound to dissolve in a given volume of solvent.
  • Hydrogen Bonding: The potential for hydrogen bonding in polar solvents, like water, is limited due to the steric hindrance of the dibutyl groups, leading to comparatively low solubility in aqueous solutions.

In summary, the solubility of 2-(dibutylamino)ethyl 4-fluorobenzoate emphasizes the significance of molecular structure in determining the behavior of compounds in different solvent environments. It can be effectively described as:

  1. More soluble in nonpolar solvents
  2. Less soluble in polar solvents

Understanding the solubility of this compound plays a critical role in its application potential in various chemical and pharmaceutical contexts.

Interesting facts

Interesting Facts about 2-(Dibutylamino)ethyl 4-fluorobenzoate

2-(Dibutylamino)ethyl 4-fluorobenzoate, a compound with intriguing properties, serves as a cornerstone in various fields of chemistry. Here are some fascinating aspects of this compound:

  • Pharmaceutical Relevance: This compound is studied for its potential applications in medicinal chemistry, specifically in developing novel therapeutic agents. The dibutylamino functional group is known for enhancing lipophilicity, which may improve the compound's ability to traverse cellular membranes.
  • Fluorine's Role: The presence of the fluorine atom in the benzoate structure can significantly influence biological activity and pharmacokinetics. Fluorine is often used in drug design to increase metabolic stability and binding affinity.
  • Synthetic Pathways: The synthesis of 2-(dibutylamino)ethyl 4-fluorobenzoate involves intricate chemical reactions, showcasing the importance of organic synthesis techniques in creating functional compounds.
  • Research Applications: Scientists are exploring this compound's efficacy in various chemical reactions, including its behavior as a catalyst in organic synthesis, further expanding its utility in the lab.
  • Spectroscopic Features: The compound can be characterized using various spectroscopic methods, including NMR and IR, allowing scientists to deduce its structure and properties effectively.

In summary, the multifaceted nature of 2-(dibutylamino)ethyl 4-fluorobenzoate makes it a subject of ongoing research interest, particularly in the realms of medicinal and organic chemistry. As exchanges of knowledge progress, this compound may unveil new pathways to innovation in drug discovery and development.