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Procaine

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Identification
Molecular formula
C13H20N2O2
CAS number
59-46-1
IUPAC name
[2-(diethylamino)-1-phenyl-ethyl] benzoate
State
State

Procaine is in a solid state at room temperature.

Melting point (Celsius)
61.00
Melting point (Kelvin)
334.15
Boiling point (Celsius)
378.00
Boiling point (Kelvin)
651.15
General information
Molecular weight
236.31g/mol
Molar mass
236.3110g/mol
Density
1.1730g/cm3
Appearence

Procaine is typically a white crystalline powder. It is odorless and has a slightly bitter taste.

Comment on solubility

Solubility of [2-(diethylamino)-1-phenyl-ethyl] benzoate

The solubility of [2-(diethylamino)-1-phenyl-ethyl] benzoate can be dissected by considering its molecular structure and the interactions it may have with various solvents. Understanding the solubility behavior of this compound is crucial for its practical applications.

Key Points on Solubility

  • Polar vs. Non-Polar Solvents: Generally, this compound displays better solubility in non-polar solvents due to its hydrophobic regions. It is less likely to dissolve in polar solvents.
  • Temperature Influence: Increased temperature can enhance the solubility of many organic compounds, and [2-(diethylamino)-1-phenyl-ethyl] benzoate is no exception. Heating the solvent can make it more favorable for dissolution.
  • Hydrogen Bonding: This compound’s ability to form hydrogen bonds can affect its solubility in polar solvents to some extent. However, due to the bulky diethylamino and phenyl groups, strong solubility in water remains limited.
  • pH Sensitivity: If the environment's pH changes, it could alter the ionization state of the diethylamino group, potentially affecting the solubility profile.

In conclusion, the solubility of [2-(diethylamino)-1-phenyl-ethyl] benzoate is influenced by various factors, including solvent choice, temperature, and molecular interactions. Understanding these dynamics can aid in predicting its behavior in different environments.

Interesting facts

Interesting Facts about [2-(diethylamino)-1-phenyl-ethyl] benzoate

[2-(diethylamino)-1-phenyl-ethyl] benzoate is a fascinating compound that intersects various disciplines, from medicinal chemistry to pharmacology. This compound, often utilized in the synthesis of pharmaceutical agents, has garnered attention due to its unique properties and applications.

Key Characteristics

  • Biological Relevance: It exhibits interesting biological activity, making it a candidate for further research in drug design.
  • Chemical Versatility: The presence of both diethylamino and phenyl groups allows it to engage in diverse chemical interactions, enhancing its functionality.
  • Substituent Influence: The structure indicates that the diethylamino group can significantly influence the compound's electronic and steric properties.

Applications

  • Commonly used as a chemical building block in the synthesis of various therapeutic agents.
  • Potential applications in the development of local anesthetics, as related compounds have similar functionalities.
  • Interest in its utility in formulating novel drug delivery systems, owing to its unique interactions.

"Exploring the structure of [2-(diethylamino)-1-phenyl-ethyl] benzoate offers insights into how small modifications can result in significant changes in bioactivity."

Research Directions

The study of this compound opens up several exciting avenues for research, including:

  • Investigating its mechanism of action in biological systems.
  • Exploring synthetic pathways to optimize yield and efficacy.
  • Assessing its potential in treating specific medical conditions, particularly in areas of pain management and anesthesia.

In summary, [2-(diethylamino)-1-phenyl-ethyl] benzoate stands out as an intriguing compound with noteworthy properties and application potentials. Its distinct structure serves as a reminder that in chemistry, the possibilities are nearly endless!

Synonyms
Elucaine
25314-87-8
Elucaina
Elucaine [USAN:INN]
Elucainum
Elucainum [INN-Latin]
Elucaina [INN-Spanish]
UNII-85EW9V00UL
2-Diethylamino-1-phenylethyl benzoate
Elucaine (USAN)
BRN 2220826
85EW9V00UL
Benzenemethanol, alpha-((diethylamino)methyl)-, benzoate (ester)
beta-Benzoyloxy-beta-phenylethyl diethylamine
ELUCAINE [USAN]
ELUCAINE [INN]
Elucaine, alpha-((diethylamino)methyl)-, benzoate (ester)
alpha-((Diethylamino)methyl)benzyl alcohol benzoate (ester)
4-13-00-01807 (Beilstein Handbook Reference)
Benzyl alcohol, alpha-(diethylaminomethyl)-, benzoate
BENZOIC ACID, 2-(DIETHYLAMINO)-1-PHENYLETHYL ESTER
Elucainum (INN-Latin)
Benzyl alcohol, alpha-((diethylamino)methyl)-, benzoate (ester)
Elucaina (INN-Spanish)
BENZENEMETHANOL, .ALPHA.-((DIETHYLAMINO)METHYL)-, BENZOATE (ESTER)
alpha-[(Diethylamino)methyl]benzyl alcohol benzoate (ester)
RefChem:136560
Benzyl alcohol, alpha-(diethylaminomethyl)-, benzoate (6CI)
.ALPHA.-((DIETHYLAMINO)METHYL)BENZYL ALCOHOL BENZOATE (ESTER)
Benzyl alcohol, alpha-((diethylamino)methyl)-, benzoate (ester) (8CI)
[2-(diethylamino)-1-phenylethyl] benzoate
SCHEMBL635291
orb1707338
CHEMBL2104229
DTXSID10865203
AKOS040741693
CS-6751
2-(Diethylamino)-1-phenylethyl benzoate
DA-63165
HY-101743
NS00120258
D03979
Q27269636