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Diethylpropion

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Identification
Molecular formula
C13H19NO
CAS number
134-80-5
IUPAC name
2-(diethylamino)-1-phenyl-propan-1-one
State
State

At room temperature, diethylpropion typically exists as a solid due to its crystalline structure.

Melting point (Celsius)
134.00
Melting point (Kelvin)
407.15
Boiling point (Celsius)
332.70
Boiling point (Kelvin)
605.85
General information
Molecular weight
205.31g/mol
Molar mass
205.3080g/mol
Density
1.0040g/cm3
Appearence

Diethylpropion is typically found as a white, crystalline powder that is odorless. It has a slightly bitter taste and can be soluble in water and alcohol. The pure compound is usually conserved in its salt form for stability and medications.

Comment on solubility

Solubility of 2-(diethylamino)-1-phenyl-propan-1-one

The solubility of 2-(diethylamino)-1-phenyl-propan-1-one can be influenced by various factors such as temperature, pH, and the presence of solvents. Understanding its solubility characteristics can be crucial for applications in different fields, particularly in pharmaceuticals and organic synthesis.

Key Points to Consider:

  • Polarity: This compound possesses both hydrophobic (aromatic) and hydrophilic (amino) regions, which can affect its solubility in different solvents.
  • Solvent Interaction: It is generally more soluble in organic solvents like ethanol, acetone, or chloroform due to its non-polar aromatic character.
  • Aqueous Solubility: Its solubility in water is limited because of the bulky diethylamino group, which increases steric hindrance and decreases the intermolecular hydrogen bonding with water molecules.

As a result, 2-(diethylamino)-1-phenyl-propan-1-one may exhibit varying solubility depending on the medium it is placed in. Understanding these factors can be essential for optimizing its use in chemical reactions and formulations.

Interesting facts

Interesting Facts About 2-(Diethylamino)-1-phenyl-propan-1-one

2-(Diethylamino)-1-phenyl-propan-1-one, commonly referred to by its abbreviation as DEAP, is an intriguing compound that finds its place in both pharmaceutical and research arenas. Here are some fascinating aspects of this chemical:

  • Structural Composition: DEAP features a propan-1-one structure, which is characteristic of ketones. Its unique arrangement of a diethylamino group attached to a phenyl ring plays a significant role in its biological activity.
  • Pharmacological Relevance: Compounds similar to DEAP are often explored for their potential as intermediates in the synthesis of various pharmaceuticals, highlighting the importance of this class of compounds in medicinal chemistry.
  • Research Applications: DEAP is also utilized in biochemical research, particularly in studies related to enzyme activity and as a reagent in organic synthesis due to its reactivity.
  • Safety Considerations: As with many amine-containing compounds, safety measures must be observed when handling DEAP, emphasizing the important role of safety protocols in chemical research.
  • Versatile Chemistry: The presence of both an amine and a ketone group provides DEAP with versatile reactivity, making it an interesting subject for synthetic chemists looking to develop new derivatives.

The chemical's dual functionality opens up pathways for exploring new compounds through positional isomerism or even modifications of the amino group. As with many organic compounds, understanding DEAP's behavior in chemical reactions contributes to our broader knowledge of organic synthesis and reactivity.

In the words of a famous chemist, “Chemistry is not about substances, it's about understanding the transformations that lead to new realities.” The study of compounds like DEAP embodies this philosophy, showcasing how intricate interactions result in diverse applications in science.

Synonyms
DIETHYLPROPION
Amfepramone
Diethylpropione
Amfepramon
Amphepramone
Nopropiophenone
90-84-6
Adiposon
Amphepramon
Frekentine
Danylen
Magrene
Tylinal
Diethylcathinone
alpha-Benzoyltriethylamine
Amfepramonum
Anfepramona
Cegramine
Obesitex
Derfon
Silutin
Dobesin
Tepanil
Anorex
alpha-Diethylaminopropiophenone
2-(Diethylamino)propiophenone
1-Propanone, 2-(diethylamino)-1-phenyl-
Prefamone
Amfepramone [INN]
Regenon
2-Diethylaminopropiophenone
Amfepramonum [INN-Latin]
Anfepramona [INN-Spanish]
2-(Diethylamino)-1-phenyl-1-propanone
2-(diethylamino)-1-phenylpropan-1-one
1-Phenyl-2-diethylamino-1-propanone
Anferpramon
Propiophenone, 2-(diethylamino)-
(+-)-diethylpropion
Anfepramone
DEA No. 1610
UR 1423
Fenyl-(1-diethylaminoethyl)keton
HSDB 3059
EINECS 202-019-1
UNII-Q94YYU22B8
Amfepramone (INN)
BRN 2804400
CHEBI:4530
Neobes
Propiophenone, 2-diethylamino-
Q94YYU22B8
Amphepramonum hydrochloride
C06954
D07444
.alpha.-benzoyltriethylamine
J4.327C
DTXSID6022929
Phepranon
4-14-00-00144 (Beilstein Handbook Reference)
Anfamon
Keramik
Keramin
Modulor
Parabolin
Amfepramonum (INN-Latin)
Anfepramona (INN-Spanish)
Tenuate hydrochloride
Diethylpropione hydrochloride
Diethylpropion (BAN)
Fenyl-(1-diethylaminoethyl)keton [Czech]
NCGC00167475-01
Diethylpropin
(+/-)-diethylpropion
AMFEPRAMONE [HSDB]
DIETHYLPROPION [MI]
SCHEMBL27330
AMFEPRAMONE [WHO-DD]
DIETHYLPROPION [VANDF]
DTXCID202929
GTPL7161
CHEMBL1194666
AKOS025401369
DB00937
AC-13099
2-(Diethylamino)-1-phenyl-1-propanone #
NS00008562
1-Phenyl-2-diethylamino-1-propanone hydrochloride
Q2356505
BRD-A37288617-003-01-4
BRD-A37288617-003-02-2
202-019-1