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2-(Diethylamino)-2-phenylacetonitrile

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Identification
Molecular formula
C12H16N2
CAS number
86-29-3
IUPAC name
2-(diethylamino)-2-phenyl-acetonitrile
State
State

At room temperature, 2-(Diethylamino)-2-phenylacetonitrile is a liquid.

Melting point (Celsius)
-33.00
Melting point (Kelvin)
240.15
Boiling point (Celsius)
286.00
Boiling point (Kelvin)
559.15
General information
Molecular weight
188.27g/mol
Molar mass
188.2680g/mol
Density
1.0020g/cm3
Appearence

2-(Diethylamino)-2-phenylacetonitrile typically appears as a colorless to pale yellow liquid. It is used as an intermediate in organic synthesis.

Comment on solubility

Solubility of 2-(diethylamino)-2-phenyl-acetonitrile

When considering the solubility of 2-(diethylamino)-2-phenyl-acetonitrile, it's essential to highlight its characteristics in both polar and non-polar solvents. Generally, the presence of the diethylamino group contributes to enhanced solubility in polar solvents compared to its non-polar counterparts. Here are some key points regarding its solubility:

  • Polar Solvents: This compound exhibits a greater affinity for polar solvents such as water and alcohols due to the ability of the diethylamino group to engage in hydrogen bonding.
  • Non-Polar Solvents: In contrast, solubility in non-polar solvents may be limited, owing to the hydrophobic nature of the phenyl ring and the diethyl groups.
  • Temperature Influence: Solubility can also be temperature-dependent; often, an increase in temperature may lead to enhanced solubility in various solvents.

Overall, while 2-(diethylamino)-2-phenyl-acetonitrile may be soluble in polar environments, its solubility profile can vary significantly based on solvation effects and solvent interactions. To quote a famous chemist, "Solubility is the key to chemical reactivity." Thus, understanding the solubility of this compound is crucial for its application in different chemical reactions and processes.

Interesting facts

Interesting Facts about 2-(Diethylamino)-2-phenyl-acetonitrile

2-(Diethylamino)-2-phenyl-acetonitrile is a noteworthy chemical compound that captivates both researchers and students in the field of chemistry for a variety of reasons:

  • Dual Functionality: This compound exhibits the characteristics of both an amine and a nitrile, allowing for versatile reactions in organic synthesis. Its dual functionality makes it a valuable intermediate in the production of pharmaceuticals and agrochemicals.
  • Pharmaceutical Applications: Due to its structural properties, 2-(diethylamino)-2-phenyl-acetonitrile can serve as a building block for various biologically active molecules, enhancing its significance in medicinal chemistry.
  • Research Interests: Chemists are interested in the compound for its potential applications in drug development and as a reagent in Diels-Alder reactions, showcasing its importance in synthetic organic chemistry.
  • Mechanism Insights: Studies surrounding this compound often involve revealing its mechanisms of interaction and reaction pathways, providing deep insights into the behavior of amine and nitrile groups under different conditions.
  • Safety Precautions: As is the case with many organic compounds, proper handling and knowledge of 2-(diethylamino)-2-phenyl-acetonitrile is critical due to its potential toxicity and reactivity. Research in safety protocols is as vital as research in chemical applications.

In conclusion, 2-(diethylamino)-2-phenyl-acetonitrile embodies a fascinating blend of complexity and utility that highlights its role in contributing to advancements in the field of chemistry. As researchers continue to explore its properties, the possibilities for innovative applications remain ever-expanding.

Synonyms
5097-99-4
2-(diethylamino)-2-phenylacetonitrile
Diethylaminophenylacetonitrile
(diethylamino)(phenyl)acetonitrile
2-(diethylamino)-2-phenyl-acetonitrile
BRN 2099346
ACETONITRILE, (DIETHYLAMINO)PHENYL-
MFCD01673030
ACETONITRILE,(DIETHYLAMINO)PHENYL-
Benzeneacetonitrile, .alpha.-(diethylamino)-
4-14-00-01322 (Beilstein Handbook Reference)
Phenyl(diethylamino)acetonitrile
DTXSID80874327
ALBB-031741
AKOS009986397
CS-10052
CS-0364786