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Quinoclamine

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Identification
Molecular formula
C14H17N3O3
CAS number
2797-51-5
IUPAC name
2-(diethylamino)-6,7-dimethoxy-1H-quinazolin-4-one
State
State

At room temperature, quinoclamine is a solid.

Melting point (Celsius)
122.00
Melting point (Kelvin)
395.15
Boiling point (Celsius)
351.00
Boiling point (Kelvin)
624.15
General information
Molecular weight
288.31g/mol
Molar mass
288.3370g/mol
Density
1.2223g/cm3
Appearence

Quinoclamine typically appears as a yellow to off-white crystalline solid. It may also be found as a fine powder depending on its form of preparation.

Comment on solubility

Solubility of 2-(diethylamino)-6,7-dimethoxy-1H-quinazolin-4-one

The solubility of 2-(diethylamino)-6,7-dimethoxy-1H-quinazolin-4-one is an important characteristic that can significantly influence its application in various fields. Understanding its solubility can be summarized as follows:

  • Solvent Compatibility: Generally, this compound is expected to be soluble in organic solvents due to the presence of the diethylamino group, which enhances its solvation properties in non-polar environments.
  • Water Solubility: Its solubility in water may be limited due to the bulky organic groups. Molecules with similar structures often show lower solubility in aqueous solutions.
  • pH Influence: The solubility can also vary with pH. The presence of the amine group might make the compound more soluble in acidic conditions, where it can become protonated.
  • Temperature Dependency: Like many organic compounds, solubility can increase with temperature; thus, it may require heating to reach optimal dissolution rates in specified solvents.

In summary, the solubility of 2-(diethylamino)-6,7-dimethoxy-1H-quinazolin-4-one highlights its versatility while posing challenges in aqueous environments. Researchers should conduct specific solubility tests to determine the most effective solvent for their needs.

Interesting facts

Interesting Facts about 2-(diethylamino)-6,7-dimethoxy-1H-quinazolin-4-one

2-(diethylamino)-6,7-dimethoxy-1H-quinazolin-4-one is a fascinating compound that has drawn significant attention in both medicinal chemistry and pharmacology. This compound belongs to the quinazolinone class of molecules, which are known for their diverse biological activities. Here are some intriguing aspects of this compound:

  • Medicinal Potential: Quinazolinones, including this compound, have been investigated for their potential therapeutic effects, particularly as antitumor, anti-inflammatory, and antibiotic agents.
  • Structure-Activity Relationship: The presence of the diethylamino group enhances the compound's lipophilicity, potentially improving its ability to cross cell membranes and interact with biological targets.
  • Mechanism of Action: Research suggests that compounds like 2-(diethylamino)-6,7-dimethoxy-1H-quinazolin-4-one may inhibit specific enzymes or receptors, which could explain their therapeutic effects.
  • Synthetic Routes: Chemists have developed various synthetic methodologies to produce this compound, highlighting the importance of selective functionalization in organic synthesis.
  • Continued Research: Ongoing studies are delving into the efficacy of this compound against various cancer cell lines, showcasing its potential as a lead compound in the development of novel anticancer therapies.

This compound exemplifies the thrilling intersection of organic chemistry and pharmacology, illustrating how modifications in molecular structure can lead to profound changes in biological activity. As researchers continue to explore the properties and applications of quinazolinone derivatives, compounds like 2-(diethylamino)-6,7-dimethoxy-1H-quinazolin-4-one may play a crucial role in advancing future medical treatments.