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Lidocaine

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Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
2-(diethylamino)-N-[[2-oxo-2-(4-phenylphenyl)ethylidene]amino]acetamide
State
State

At room temperature, Lidocaine exists as a solid.

Melting point (Celsius)
68.00
Melting point (Kelvin)
341.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
234.34g/mol
Molar mass
234.3370g/mol
Density
1.0260g/cm3
Appearence

Lidocaine typically appears as a white crystalline powder. It is odorless and has a slightly bitter taste.

Comment on solubility

Solubility of 2-(diethylamino)-N-[[2-oxo-2-(4-phenylphenyl)ethylidene]amino]acetamide

The solubility of the compound 2-(diethylamino)-N-[[2-oxo-2-(4-phenylphenyl)ethylidene]amino]acetamide can be characterized by several factors:

  • Polar and Nonpolar Characteristics: Given that this compound contains both polar functional groups (like the amide) and nonpolar aromatic segments, its solubility is likely to vary in different solvents.
  • Solvent Selection: It is expected to be more soluble in polar solvents such as methanol or dimethyl sulfoxide (DMSO) but may show lower solubility in nonpolar solvents.
  • Temperature Influence: Temperature can play a significant role in solubility, with higher temperatures usually improving solubility in most organic solvents.
  • pH Variability: The solubility may also change with pH, particularly in aqueous solutions, due to ionization of the amine groups.

In summary, the solubility of this compound can be influenced by multiple factors including solvent choice, temperature, and pH levels. It highlights the complexity of solubility in organic chemistry, as compounds can exhibit unique behaviors based on their structure and the environment.

Interesting facts

Interesting Facts about 2-(Diethylamino)-N-[[2-Oxo-2-(4-phenylphenyl)ethylidene]amino]acetamide

This compound, known for its intriguing structure, showcases the fascinating interplay between organic chemistry and medicinal applications. Here are some noteworthy aspects:

  • Dual Functionality: The presence of both a diethylamino group and an acetamide functional group allows this compound to exhibit properties typical of both amines and amides, providing a versatile chemical reactivity profile.
  • Potential in Drug Development: Compounds featuring similar structures have been investigated for their potential as drug candidates, particularly in the realms of anti-cancer and anti-inflammatory therapies. The unique structural components can influence biological activity, making it a topic of interest for pharmaceutical research.
  • Structural Complexity: Its complex architecture includes a ketone group and a phenyl ring, which can play significant roles in influencing the compound's interaction with biological targets. This complexity highlights the importance of medicinal chemistry in synthesizing biologically relevant compounds.
  • Synthetic Pathways: The synthesis of this compound could involve multi-step organic reactions, showcasing the creativity and precision required in synthetic organic chemistry. Understanding these pathways is crucial for any chemist working in drug design.
  • Research Applications: The investigation of such compounds can lead to a deeper understanding of structure-activity relationships (SAR) in drug development, enabling scientists to optimize the efficacy and reduce side effects of new medications.

In conclusion, 2-(diethylamino)-N-[[2-oxo-2-(4-phenylphenyl)ethylidene]amino]acetamide is more than just a chemical formula; it represents a fusion of organic chemistry and pharmacology. By exploring its properties and potential applications, scientists can further the progress in medical science.