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Lidocaine

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Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
2-(diethylamino)-N-(2,4-dimethylphenyl)acetamide
State
State

At room temperature, lidocaine exists as a solid in the form of crystalline powder.

Melting point (Celsius)
68.00
Melting point (Kelvin)
341.00
Boiling point (Celsius)
350.80
Boiling point (Kelvin)
623.80
General information
Molecular weight
234.34g/mol
Molar mass
234.3370g/mol
Density
1.0260g/cm3
Appearence

Lidocaine appears as a white to slightly yellow crystalline powder. It is odorless and has a slightly bitter taste.

Comment on solubility

Solubility of 2-(diethylamino)-N-(2,4-dimethylphenyl)acetamide

The solubility of 2-(diethylamino)-N-(2,4-dimethylphenyl)acetamide is influenced by several factors due to its unique chemical structure. This compound exhibits:

  • Polar Characteristics: The presence of the diethylamino group imparts some polarity, which may enhance solubility in polar solvents like water.
  • Non-Polar Attributes: The aromatic ring and alkyl groups contribute to hydrophobic interactions, potentially limiting solubility in highly polar solvents.
  • Solvent Dependency: It is more likely to be soluble in organic solvents such as ethanol, methanol, and chloroform due to its non-polar components.

In general, the solubility behavior of this compound can be summarized as follows:

  1. The compound is expected to have moderate solubility in water.
  2. It is likely to be more soluble in organic solvents.
  3. Temperature may also affect solubility, as higher temperatures can improve dissolution rates.

As with many organic compounds, experimental determination of solubility is essential, as predictions can sometimes vary based on specific conditions and solvent interactions. Thus, one may observe that solubility characteristics may vary widely depending on the specific experimental setup.

Interesting facts

Intriguing Facts About 2-(Diethylamino)-N-(2,4-dimethylphenyl)acetamide

2-(Diethylamino)-N-(2,4-dimethylphenyl)acetamide, also known within certain research circles as a versatile compound in synthetic organic chemistry, presents numerous interesting characteristics that pique the curiosity of both scientists and students alike.

Key Features:

  • Versatile Applications: This compound is primarily applied in the field of medicinal chemistry and pharmaceuticals, where it serves as a building block for developing numerous **bioactive agents**.
  • Structural Significance: The presence of the diethylamino group greatly enhances the compound's ability to interact with biological systems, making it a subject of study for potential pharmacological uses.
  • Synthetic Routes: Synthesis of this compound often incorporates unique methods such as amide bond formation, which showcases the beauty of chemical transformations.

Moreover, it’s worth noting that the structural complexity of 2-(diethylamino)-N-(2,4-dimethylphenyl)acetamide allows for a range of derivatives to be synthesized, each having distinct properties and potential activities. This versatility sparks a lot of excitement among researchers striving to uncover new applications.

Research Insights:

  • Pharmacological Potential: Investigations are ongoing into how variations in its structure can influence its **therapeutic efficacy**.
  • Mechanistic Studies: Research into how this compound interacts at the molecular level can unveil insights into its efficacy and safety profiles.

In conclusion, 2-(diethylamino)-N-(2,4-dimethylphenyl)acetamide exemplifies the intricate dance of chemical structure and biological activity, making it a fascinating topic for study and a promising candidate for future research breakthroughs.

Synonyms
2-(Diethylamino)-2',4'-acetoxylidide
2-(diethylamino)-N-(2,4-dimethylphenyl)acetamide
Acetamide, 2-(diethylamino)-N-(2,4-dimethylphenyl)-
BRN 2648763
UNII-1JI90526PD
2',4'-ACETOXYLIDIDE, 2-(DIETHYLAMINO)-
1JI90526PD
DTXSID60169420
4-12-00-02556 (Beilstein Handbook Reference)
LIDOCAINE IMPURITY I [EP IMPURITY]
LIDOCAINE HYDROCHLORIDE IMPURITY I [EP IMPURITY]
LIDOCAINE IMPURITY I (EP IMPURITY)
LIDOCAINE HYDROCHLORIDE IMPURITY I (EP IMPURITY)
DTXCID7091911
17289-53-1
LIDOCAINE EP IMPURITY I
CHEMBL255831
SCHEMBL2098794
SCHEMBL30817424
SAA28953
STL231520
AKOS002844139
EU-0001446
ST45184325
G87707
SR-01000400047
SR-01000400047-1
Q27252504
Z55135893
Lidocaine EP Impurity I(Discontinued,See C4X-16799)
N-(2,4-dimethylphenyl)-N~2~,N~2~-diethylglycinamide