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Lidocaine

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Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
2-(diethylamino)-N-[4-[[2-(diethylamino)acetyl]amino]-5-oxo-cyclohepta-1,3,6-trien-1-yl]acetamide
State
State

At room temperature, lidocaine is typically a solid. It is often available in crystalline powder form but can also be found in solution for medical applications.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.15
Boiling point (Celsius)
180.00
Boiling point (Kelvin)
453.15
General information
Molecular weight
234.34g/mol
Molar mass
234.3390g/mol
Density
1.0260g/cm3
Appearence

Lidocaine appears as a white to slightly yellow crystalline powder. It is odorless or has a slight characteristic odor.

Comment on solubility

Solubility of 2-(diethylamino)-N-[4-[[2-(diethylamino)acetyl]amino]-5-oxo-cyclohepta-1,3,6-trien-1-yl]acetamide

The solubility of 2-(diethylamino)-N-[4-[[2-(diethylamino)acetyl]amino]-5-oxo-cyclohepta-1,3,6-trien-1-yl]acetamide can be influenced by various factors. This compound contains multiple functional groups that can interact with different solvents, making its solubility behavior quite interesting.

Factors Affecting Solubility:

  • Polarity: The presence of diethylamino groups suggests that the compound may exhibit some level of polarity, potentially enhancing solubility in polar solvents.
  • Hydrogen Bonding: Given the amide functional groups, the ability to form hydrogen bonds can significantly affect its interactions with water and organic solvents.
  • Size and Structure: The bulky structure from the cycloheptatriene moiety may hinder solubility in certain solvents, particularly non-polar ones.

To summarize, the solubility of this compound is expected to vary depending on the solvent used. It may dissolve well in polar solvents like water or ethanol due to hydrogen bonding capabilities, while exhibiting lower solubility in non-polar solvents due to its inherent structural constraints. As noted, "the interplay of structural features and solvent interactions is crucial in determining solubility." Experimentally determining solubility in various media will provide a comprehensive understanding of its behavior in different environments.

Interesting facts

Interesting Facts about 2-(Diethylamino)-N-[4-[[2-(diethylamino)acetyl]amino]-5-oxo-cyclohepta-1,3,6-trien-1-yl]acetamide

This complex compound, known for its intricate structure and interesting properties, belongs to the class of organic compounds often studied in medicinal chemistry. Here are some fascinating insights:

  • Multi-functional Roles: The presence of two diethylamino groups suggests potential for multiple interactions within biological systems. These functional groups enhance solubility and stability, making the compound an attractive candidate in drug formulation.
  • Structure-Activity Relationship: The compound's cyclic structure, particularly the cycloheptatriene part, contributes to its unique reactivity and biological activity, which can be essential in designing new therapeutic agents.
  • Potential Medicinal Applications: Compounds with similar structures are often investigated for their anti-cancer or anti-inflammatory properties. This highlights the importance of such compounds in the pharmaceutical realm.
  • Synthetic Challenge: The synthesis of such compounds can be complex, often requiring multiple steps and careful control of reaction conditions, which makes studying their synthesis an invaluable part of organic chemistry education.
  • Research Insights: Continuous research on compounds like this one can lead to breakthroughs in understanding drug mechanisms and developing new treatments. As noted in scientific journals, "the exploration of novel compounds drives innovation in pharmacology."

This compound serves as a prime example of how intricate molecular designs can lead to profound implications in medicinal chemistry, paving the way for future research and development.

Synonyms
2,5-Bis(diethylaminoacetamido)tropone
BRN 2775992
ACETAMIDE, N,N'-(7-OXO-1,3,5-CYCLOHEPTATRIEN-1,4-YLENE)BIS(2-(DIETHYLAMINO)-
18188-78-8
DTXSID00171204
N,N'-(7-Oxo-1,3,5-cycloheptatrien-1,4-ylene)bis(2-(diethylamino)acetamide)
DTXCID4093695