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Paracetamol

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Identification
Molecular formula
C8H9NO2
CAS number
103-90-2
IUPAC name
2-(diethylamino)-N-(4-hydroxyphenyl)-N-methyl-acetamide
State
State

At room temperature, paracetamol is in a solid state. It is commonly encountered as tablets or capsules for pharmaceutical use.

Melting point (Celsius)
169.00
Melting point (Kelvin)
442.15
Boiling point (Celsius)
327.20
Boiling point (Kelvin)
600.35
General information
Molecular weight
151.16g/mol
Molar mass
151.1630g/mol
Density
1.2630g/cm3
Appearence

Paracetamol typically appears as a white crystalline powder. It is odorless and has a bitter taste. The compound is often formed into tablets or capsules for medicinal use due to its powdered form.

Comment on solubility

Solubility of 2-(diethylamino)-N-(4-hydroxyphenyl)-N-methyl-acetamide

The solubility of 2-(diethylamino)-N-(4-hydroxyphenyl)-N-methyl-acetamide can be quite intriguing due to its intricate structure. This compound, often utilized in various chemical applications, presents characteristics that influence its solubility in various solvents.

Key Factors Affecting Solubility:

  • Polarity: The presence of both the diethylamino group and the hydroxyl group contributes to the overall polarity of the molecule, enhancing its ability to interact with polar solvents such as water and alcohols.
  • Hydrogen Bonding: The hydroxyl (-OH) group can engage in hydrogen bonding, which generally increases solubility in polar media.
  • Chain Length: The length of the diethylamino chain may influence the compound's hydrophobic characteristics, possibly reducing solubility in highly polar solvents.
  • Temperature: Solubility can vary significantly with temperature; generally, higher temperatures increase solubility for many compounds.

In summary, this compound likely exhibits good solubility in polar organic solvents while demonstrating reduced solubility in non-polar solvents. As with many organic compounds, the exact solubility can vary considerably depending on the specific conditions present, making it essential for practitioners to assess solubility in their particular applications.

Interesting facts

Interesting Facts about 2-(diethylamino)-N-(4-hydroxyphenyl)-N-methyl-acetamide

2-(diethylamino)-N-(4-hydroxyphenyl)-N-methyl-acetamide, commonly referred to in research contexts for its complex structure and potential applications, is a fascinating compound in the realm of organic chemistry. Here are some notable aspects:

  • Pharmacological Significance: This compound belongs to a class of molecules that may exhibit interesting pharmacological properties. The presence of the hydroxy group and the diethylamino moiety can play pivotal roles in receptor interaction, potentially influencing the efficacy of drug action.
  • Chemical Versatility: With numerous functional groups within its structure, this compound can serve as a useful intermediate in various synthetic pathways. Its ability to undergo reactions such as acylation or nucleophilic substitution makes it a valuable building block in medicinal chemistry.
  • Structural Intricacies: The molecular structure reveals a alignment of diethylamino and hydroxy groups. These structural features contribute to the compound’s unique properties, allowing for potential applications in the development of targeted therapies.
  • Research Applications: In scientific studies, this compound has been researched for its potential roles in developing novel analgesics and anti-inflammatory agents. Its structural similarity to known pharmaceuticals invites further exploration and optimization in drug design.
  • Synergistic Effects: The combination of diethylamino and hydroxyphenyl functionalities can lead to synergistic effects, enhancing biological activity compared to simpler compounds. This characteristic is particularly important in developing compounds with improved pharmacokinetic profiles.

As a result, the exploration of 2-(diethylamino)-N-(4-hydroxyphenyl)-N-methyl-acetamide continues to captivate scientists and fuels ongoing research aimed at harnessing its potential therapeutic properties.

Synonyms
ACETANILIDE, 2-(DIETHYLAMINO)-4'-HYDROXY-N-METHYL-
3614-03-7
M & B 5623
DTXSID10189714
2-(Diethylamino)-4'-hydroxy-N-methylacetanilide
DTXCID70112205
2-(diethylamino)-N-(4-hydroxyphenyl)-N-methylacetamide
starbld0022438
AKOS040750078