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Lidocaine

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Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
2-(diethylamino)-N-(4-isopropylphenyl)acetamide
State
State

At room temperature, lidocaine is typically in a solid state as a crystalline powder. It is stable under ordinary conditions of use and storage.

Melting point (Celsius)
68.00
Melting point (Kelvin)
341.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
234.34g/mol
Molar mass
234.3390g/mol
Density
1.0260g/cm3
Appearence

Lidocaine typically appears as a white to slightly yellow crystalline powder. It is odorless and has a slightly bitter taste. The compound is soluble in alcohol, ether, and chloroform but slightly soluble in water.

Comment on solubility

Solubility of 2-(diethylamino)-N-(4-isopropylphenyl)acetamide

The solubility of 2-(diethylamino)-N-(4-isopropylphenyl)acetamide in various solvents is quite intriguing and can be understood through several key points:

  • Polar vs. Non-Polar Solvents: Due to the presence of both polar and non-polar functional groups in its structure, this compound is likely to exhibit varying solubility. It tends to dissolve better in polar solvents such as water and alcohols than in non-polar solvents.
  • pH Influence: The solubility may also be affected by the pH of the solvent. In basic conditions, the amine groups can become protonated, enhancing solubility.
  • Temperature Effects: Increasing temperature often improves solubility for most organic compounds. 2-(diethylamino)-N-(4-isopropylphenyl)acetamide may follow this trend, leading to greater dissolution in warm solvents.
  • Concentration Factors: As concentration increases, the solubility limit can be reached, beyond which the compound may precipitate in solution.

In conclusion, understanding the solubility of 2-(diethylamino)-N-(4-isopropylphenyl)acetamide is essential, as it influences its bioavailability and effectiveness in various applications. The interplay of solvent properties, concentration, and temperature conditions makes solubility a complex yet fascinating aspect of this compound.

Interesting facts

Interesting Facts about 2-(diethylamino)-N-(4-isopropylphenyl)acetamide

The compound 2-(diethylamino)-N-(4-isopropylphenyl)acetamide is a fascinating example in the field of medicinal chemistry. This compound belongs to a class of compounds that have exhibited significance in various biological applications, and as such, is noteworthy for its safety and efficacy profiles in pharmacology.

Key Characteristics

  • Pharmacological Potential: Research indicates that compounds like this one may possess unique pharmacological properties, making them candidates for therapeutic applications, particularly as analgesics or anxiolytics.
  • Structural Diversity: The presence of the diethylamino group contributes to the compound's unique solubility and reactivity patterns. The isopropylphenyl moiety may influence the compound's binding affinity and selectivity towards various receptors.
  • Synthetic Routes: Synthetic chemists are keenly interested in constructing such molecules, as they may employ innovative techniques and reagents to optimize the yield and purity of the compound, which is critical for its development.

Moreover, this compound is an example of how slight modifications in chemical structure can lead to significant variations in biological activity. The exploration of similar compounds has expanded our understanding of structure-activity relationships (SAR), paving the way for the discovery of new therapeutic agents.

As chemists continue to explore the depths of medicinal chemistry, the dual nature of 2-(diethylamino)-N-(4-isopropylphenyl)acetamide highlights the essence of scientific inquiry: "Every compound has a story, waiting to be discovered."

In conclusion, the study of this intriguing compound not only enhances our knowledge of chemical compounds but also emphasizes the importance of innovative research in developing future medications.