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Lidocaine

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Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
2-(diethylamino)-N-(5-ethyl-2-methoxy-phenyl)acetamide
State
State

Lidocaine is typically found in a solid state at room temperature and is very soluble in water, making it useful for medical applications in solution form.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.20
Boiling point (Celsius)
350.80
Boiling point (Kelvin)
623.90
General information
Molecular weight
234.34g/mol
Molar mass
234.3360g/mol
Density
1.0300g/cm3
Appearence

Lidocaine appears as a white crystalline powder, often showing a nearly pure white color.

Comment on solubility

Solubility of 2-(diethylamino)-N-(5-ethyl-2-methoxy-phenyl)acetamide

The solubility characteristics of 2-(diethylamino)-N-(5-ethyl-2-methoxy-phenyl)acetamide can provide valuable insights into its potential applications and behavior in different environments. This compound exhibits moderate solubility in polar solvents, primarily due to the presence of functional groups that can engage in hydrogen bonding.

Key factors influencing its solubility include:

  • Polarity: The amine and methoxy groups enhance the polarity of the compound, allowing for interactions with water molecules.
  • Hydrogen Bonding: The ability to form hydrogen bonds increases solubility in polar solvents.
  • Molecular Weight: As a relatively complex molecule, its larger size may hinder solubility in non-polar solvents.

In summary, while 2-(diethylamino)-N-(5-ethyl-2-methoxy-phenyl)acetamide demonstrates solubility in polar mediums, it is less soluble in non-polar solvents, making it essential to consider solvent choice when preparing solutions or conducting reactions. Understanding the solubility of this compound aids in predicting its behavior in biological systems and chemical processes.

Interesting facts

Interesting Facts about 2-(Diethylamino)-N-(5-ethyl-2-methoxy-phenyl)acetamide

2-(Diethylamino)-N-(5-ethyl-2-methoxy-phenyl)acetamide is a fascinating compound that is often studied in the fields of medicinal chemistry and pharmacology. Here are some key points about this intriguing molecule:

  • Structural Significance: This compound features a unique combination of an amine and an acetamide functional group, which plays a crucial role in its pharmacological activity.
  • Potential Applications: Research into compounds similar to this one suggests potential uses in the treatment of various conditions, potentially including neurological and psychiatric disorders.
  • Synthetic Pathways: The synthesis of this compound is of interest to organic chemists, as it involves elegant reaction mechanisms that are teaching tools for students learning about amine chemistry.
  • Biological Studies: Some derivatives of similar structures have shown promise in biological assays, highlighting the importance of structure-activity relationships (SAR) in drug design.
  • Interdisciplinary Relevance: This compound can serve as a bridge between organic chemistry, biology, and pharmacology, showcasing how different scientific disciplines converge in the search for new therapeutic agents.

As a remarkable example of how chemical structure influences biological activity, 2-(diethylamino)-N-(5-ethyl-2-methoxy-phenyl)acetamide continues to inspire ongoing research and curiosity in the scientific community. Its study not only enhances our understanding of medicinal properties but also fosters innovation in drug discovery.

Synonyms
BRN 2811073
o-ACETANISIDIDE, 2-(DIETHYLAMINO)-5'-ETHYL-
2-(Diethylamino)-5'-ethyl-o-acetanisidide
3117-20-2
alpha-Diaethylamino-3-aethyl-6-methoxy-acetanilid [German]
DTXSID10185099
4-13-00-01785 (Beilstein Handbook Reference)
alpha-Diaethylamino-3-aethyl-6-methoxy-acetanilid
DTXCID70107590