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Lidocaine

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Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
2-(diethylamino)-N-(p-tolyl)acetamide
State
State

At room temperature, lidocaine is normally a solid in the form of a crystalline powder. However, it can be dissolved into solutions for pharmaceutical applications.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.00
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.00
General information
Molecular weight
234.34g/mol
Molar mass
234.3390g/mol
Density
1.0260g/cm3
Appearence

Lidocaine typically appears as a white to almost white, crystalline powder. It may also be available in the form of a colorless, transparent, aqueous solution when used for medical purposes.

Comment on solubility

Solubility of 2-(diethylamino)-N-(p-tolyl)acetamide

The solubility of the compound 2-(diethylamino)-N-(p-tolyl)acetamide, often abbreviated as DEAT, plays a significant role in its application and behavior in various environments. Understanding its solubility is essential for practical uses.

Key Factors Influencing Solubility:

  • Polarity: As a compound with amino and aromatic groups, DEAT exhibits varying polarity, which affects its interaction with solvents.
  • Temperature: Solubility may increase with temperature for many organic compounds, including DEAT.
  • Solvent Choice: DEAT is likely to be more soluble in polar organic solvents such as ethanol or methanol compared to non-polar solvents.

For practical applications, the solubility of DEAT can be described as:

  • Moderately soluble in organic solvents like ethanol and acetone,
  • Poorly soluble in water, rendering it less effective in aqueous formulations.

Overall, the understanding of DEAT's solubility characteristics is crucial for optimizing its use in pharmaceutical and chemical syntheses. Its solubility behavior, influenced by structural components and environmental factors, can lead to enhanced efficacy when appropriately selected solvents are utilized.

Interesting facts

Exploring 2-(diethylamino)-N-(p-tolyl)acetamide

2-(diethylamino)-N-(p-tolyl)acetamide is a fascinating compound that has garnered attention in the fields of organic chemistry and medicine. This compound belongs to the class of amide derivatives, distinguished by the presence of an acetamide functional group combined with a diethylamino group. Its versatile structure offers a wide range of applications, making it a significant area of study.

Key Characteristics and Applications:

  • Pharmacological Interest: Due to its unique chemical structure, this compound is often investigated for its potential as a pharmacological agent. It has been explored for activities such as anti-inflammatory and analgesic properties.
  • Synthetic Utility: The ability to modify both the amine and acetamide components allows researchers to develop various derivatives, enhancing its synthetic utility in organic synthesis.
  • Research Relevance: It serves as a useful intermediate in the synthesis of more complex molecules that could possibly lead to the discovery of new drugs.

One of the interesting aspects of 2-(diethylamino)-N-(p-tolyl)acetamide is its relationship to the broader category of amides, known for their stability and versatility. The presence of the p-tolyl group introduces hydrophobic characteristics, making it an intriguing candidate for studies on drug delivery systems and the development of targeted therapies. As researchers continue to explore its potential, the compound highlights not only the complexity of organic synthesis but also the importance of functional groups in driving biological activity.

In summary, 2-(diethylamino)-N-(p-tolyl)acetamide stands as a remarkable example of how intricate chemical structures can lead to valuable applications in medicine and chemistry. As quote goes, "The beauty of chemistry lies in its infinite possibilities."

Synonyms
2-Diethylamino-N-p-tolyl-acetamide
65446-96-0
Acetamide, 2-(diethylamino)-N-(4-methylphenyl)-
DTXSID70274812
CTBHSLXUHNIPDV-UHFFFAOYSA-N
AKOS002844583