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Amiodarone

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Identification
Molecular formula
C25H29I2NO3
CAS number
1951-25-3
IUPAC name
2-(diethylamino)ethyl 2-[3,5-diiodo-4-(3-iodo-4-methoxy-phenoxy)phenyl]acetate
State
State

At room temperature, Amiodarone is in a solid state.

Melting point (Celsius)
157.00
Melting point (Kelvin)
430.15
Boiling point (Celsius)
557.20
Boiling point (Kelvin)
830.20
General information
Molecular weight
645.32g/mol
Molar mass
645.3190g/mol
Density
1.3340g/cm3
Appearence

Amiodarone is typically a white or slightly yellow crystalline powder.

Comment on solubility

Solubility of 2-(diethylamino)ethyl 2-[3,5-diiodo-4-(3-iodo-4-methoxy-phenoxy)phenyl]acetate

The solubility of 2-(diethylamino)ethyl 2-[3,5-diiodo-4-(3-iodo-4-methoxy-phenoxy)phenyl]acetate can be influenced by various factors due to its complex structure. Understanding its solubility profile is crucial for applications in pharmaceuticals and research.

Factors Affecting Solubility

  • Polarity: The presence of polar functional groups in the molecule can enhance solubility in polar solvents like water.
  • Hydrophobic Character: The iodo and methoxy groups may impart a degree of hydrophobicity, potentially affecting solubility in organic solvents.
  • Temperature: Increased temperature may lead to greater solubility, particularly for solid compounds.
  • pH Levels: Changes in pH can alter the ionization of the amine groups, affecting solubility in aqueous solutions.

In practice, one might find that:

  • The compound could be soluble in organic solvents such as ethanol or dimethyl sulfoxide (DMSO).
  • It may show limited solubility in water due to its lipophilic nature.

In conclusion, you might say that "the solubility of this compound is a balance between its polar and non-polar characteristics." This complexity suggests that experimentation is necessary to determine the optimal conditions for solubility in various solvents.

Interesting facts

Interesting Facts about 2-(diethylamino)ethyl 2-[3,5-diiodo-4-(3-iodo-4-methoxy-phenoxy)phenyl]acetate

The compound 2-(diethylamino)ethyl 2-[3,5-diiodo-4-(3-iodo-4-methoxy-phenoxy)phenyl]acetate, commonly recognized for its unique structure and diverse applications, holds a significant place in the world of medicinal chemistry.

Key Characteristics

  • Complex Structure: This compound features multiple functional groups including diethylamino, iodo, and methoxy, which contribute to its potential biological activity.
  • Biological Importance: Compounds containing iodine are often studied for their role in pharmaceuticals. Iodinated compounds are frequently utilized in radioisotope therapy and imaging due to their radioactivity and ability to target specific tissues.

Applications

  • Pharmaceutical Development: The structural components suggest that it may have applications in drug design, specifically in areas targeting cellular receptors or pathways.
  • Synthesis of Analogues: The compound serves as a valuable template for synthesizing analogues that may enhance efficacy or selectivity in therapeutic applications.

Research Perspectives

This compound's intriguing structure opens doors to various research opportunities such as:

  • Investigation into its mechanism of action and how it interacts at the molecular level with biological targets.
  • Exploration of its potential use as a contrast agent in imaging techniques.
  • Development of derivatives that could lead to the discovery of new therapeutic agents.

In conclusion, 2-(diethylamino)ethyl 2-[3,5-diiodo-4-(3-iodo-4-methoxy-phenoxy)phenyl]acetate represents a fascinating blend of chemistry and therapy, encouraging scientists to delve deeper into its properties and potential applications. The continued study of such compounds is vital for advancing drug discovery and development.

Synonyms
THYROMEDAN
TYROMEDAN
Tyromedan [INN]
tiromedan
UNII-9MU67I9K5I
9MU67I9K5I
DTXSID10165199
SKF 13364-A
SKF 13364
Benzeneacetic acid, 3,5-diiodo-4-(3-iodo-4-methoxyphenoxy)-, 2-(diethylamino)ethyl ester
2-(DIETHYLAMINO)ETHYL (3,5-DIIODO-4-(3-IODO-4-METHOXYPHENOXY)PHENYL)ACETATE
tyromedanum
DTXCID6087690
15301-96-9
2-(diethylamino)ethyl 2-[3,5-diiodo-4-(3-iodo-4-methoxyphenoxy)phenyl]acetate
CHEMBL2111061
SCHEMBL29385284
2-diethylaminoethyl2-[3,5-diiodo-4-(3-iodo-4-methoxyphenoxy)phenyl]acetate
NS00120750
Q27272757