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Lidocaine

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Identification
Molecular formula
C14H22ClNO2
CAS number
137-58-6
IUPAC name
2-(diethylamino)ethyl 2-chloro-2,2-diphenyl-acetate
State
State

At room temperature, lidocaine is typically a solid when in its pure, base form. However, it is often available in an aqueous solution for medical purposes, where it is a liquid.

Melting point (Celsius)
68.00
Melting point (Kelvin)
341.00
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.00
General information
Molecular weight
324.85g/mol
Molar mass
324.8450g/mol
Density
1.0450g/cm3
Appearence

Lidocaine is typically found as a white to slightly yellow, crystalline powder. It is odorless and has a slightly bitter taste. In its pure form, lidocaine appears as a solid, but it is commonly available in various formulations such as gels, patches, and injectable solutions.

Comment on solubility

Solubility of 2-(diethylamino)ethyl 2-chloro-2,2-diphenyl-acetate

The solubility of 2-(diethylamino)ethyl 2-chloro-2,2-diphenyl-acetate, often abbreviated as DEAE-Cl-DPA, presents some intriguing characteristics that are worth exploring. Being a complex organic compound, its solubility can be influenced by several factors:

  • Polarity: This compound features both polar and nonpolar sections, impacting its solubility in various solvents.
  • Solvation: The presence of the diethylamino group suggests it may interact favorably with polar solvents, while the phenyl rings denote a propensity for solubility in non-polar conditions.
  • Solvent Effects: Common solvents to consider include:
    • Water: Likely limited solubility due to hydrophobic character.
    • Ethyl alcohol: Potentially better solubility due to the polar nature of alcohol.
    • Dichloromethane: May offer improved dissolution owing to its non-polar environment.

In summary, the solubility of 2-(diethylamino)ethyl 2-chloro-2,2-diphenyl-acetate is context-dependent, and understanding its behavior in different solvents can unlock pathways to various applications. As the phrase goes, "like dissolves like," making the choice of solvent crucial for any practical uses of this compound.

Interesting facts

Interesting Facts about 2-(Diethylamino)ethyl 2-chloro-2,2-diphenyl-acetate

2-(Diethylamino)ethyl 2-chloro-2,2-diphenyl-acetate, commonly referred to in the scientific community for its importance in medicinal chemistry, is a fascinating compound with multiple applications and characteristics. Here are some notable points about this compound:

  • Pharmacological Significance: This compound has potential usefulness in studying drug interactions and effects on neurotransmitter systems, particularly in the field of neuropharmacology.
  • Synthesis: The synthesis of this compound often involves multi-step reaction processes that highlight the intricacies of organic chemistry. Researchers engage in creative problem-solving to optimize yields and purity of the final product.
  • Structural Insights: The presence of the diethylamino group is crucial, as it can enhance the compound's ability to cross lipid membranes, making it relevant in drug design.
  • Applications: Due to its structural features, this compound can serve as a building block for more complex molecules, opening avenues for innovative therapeutic agents.
  • Sustainability Considerations: As environmental concerns grow, more scientists are looking at green chemistry methods for the synthesis of compounds like this one, reducing hazardous waste and improving overall chemical processes.

In the words of a famous chemist, “Chemistry is the science of matter, but we are also concerned with the changes that matter undergoes.” 2-(Diethylamino)ethyl 2-chloro-2,2-diphenyl-acetate exemplifies how the transformation of simple organic reactants can lead to complex and useful substances that impact various fields.

Synonyms
Diaphen
6699-38-3
BRN 2156820
2-(Diethylamino)ethyl alpha-chlorodiphenylacetate
Chlorodiphenylacetic acid 2-(diethylamino)ethyl ester
Benzeneacetic acid, alpha-chloro-alpha-phenyl-, 2-(diethylamino)ethyl ester
alpha-Chlorodiphenyl acetic acid 2-(diethylamino)ethyl ester
ACETIC ACID, CHLORODIPHENYL-, 2-(DIETHYLAMINO)ETHYL ESTER
4-09-00-02509 (Beilstein Handbook Reference)
alpha-Chloro-alpha-phenylbenzeneacetic acid 2-(diethylamino)ethyl ester
2-[2-Chloro-2,2-di(phenyl)acetyl]oxyethyl-diethylazanium chloride
8L6ED83WXU
2-(diethylamino)ethyl 2-chloro-2,2-diphenylacetate
DTXSID00985803
beta-diethylaminoethyl chlorodiphenylacetate
2-(diethylamino)ethyl chloro(diphenyl)acetate
2-(Diethylamino)ethyl alpha-chloro-alpha-phenylbenzeneacetate