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2-(Diethylamino)ethyl 2-ethoxy-5-fluorobenzoate

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Identification
Molecular formula
C16H22FNO3
CAS number
24444-06-2
IUPAC name
2-(diethylamino)ethyl 2-ethoxy-5-fluoro-benzoate
State
State

This compound is generally found in a liquid state at room temperature.

Melting point (Celsius)
-20.40
Melting point (Kelvin)
252.75
Boiling point (Celsius)
351.50
Boiling point (Kelvin)
624.65
General information
Molecular weight
299.36g/mol
Molar mass
299.3560g/mol
Density
1.1150g/cm3
Appearence

This compound is typically a colorless or pale yellow liquid. It is classified as an ester compound and is characterized by its aromatic structure, which includes a benzene ring substituted with a fluorine atom, ethoxy group, and a diethylaminoethyl chain attached to the ester linkage.

Comment on solubility

Solubility of 2-(diethylamino)ethyl 2-ethoxy-5-fluoro-benzoate

The solubility of 2-(diethylamino)ethyl 2-ethoxy-5-fluoro-benzoate is influenced by several factors, including its molecular structure and the presence of functional groups. This compound exhibits interesting solubility characteristics:

  • Polarity: Due to the presence of the diethylamino group, the compound has polar characteristics, which can enhance its solubility in polar solvents.
  • Functional Groups: The ethoxy group adds to its solubilizing ability, particularly in organic solvents, while the fluorine substituent may affect solubility through its electronegative nature.
  • Interactions: This compound can engage in hydrogen bonding, which generally increases solubility in protic solvents.

In general, the solubility can be summarized as follows:

  1. Soluble in polar organic solvents like ethanol and methanol.
  2. Moderately soluble in water due to the presence of the polar amine group, though the large hydrophobic aromatic system may limit solubility.
  3. Insoluble in non-polar solvents such as hexane.

Nonetheless, empirical testing is recommended to ascertain the precise solubility characteristics in various solvents due to the complex nature of solute-solvent interactions. Understanding these solubility properties can provide valuable insights for applications in pharmaceuticals and material sciences.

Interesting facts

Interesting Facts about 2-(Diethylamino)ethyl 2-Ethoxy-5-Fluoro-Benzoate

2-(Diethylamino)ethyl 2-ethoxy-5-fluoro-benzoate is a fascinating compound with a variety of interesting applications and properties. Here are some key points to consider:

  • Pharmaceutical Potential: This compound is often explored for its potential use in medicinal chemistry, as it serves as a scaffold for designing new pharmaceuticals.
  • Fluorine's Role: The presence of fluorine in its structure can significantly enhance the bioactivity of molecules, making it a valuable element in drug design.
  • Amine Functionality: The diethylamino group enables this compound to exhibit interesting properties such as solubility and binding affinity, making it a candidate for various biological evaluations.
  • Synthetic Utility: Its unique structure allows it to be utilized in synthetic organic chemistry, enabling chemists to create derivatives that could lead to new chemical entities.

The synthesis and study of such compounds highlight the importance of understanding structure-activity relationships in drug development. As stated by many chemists, "The design of new compounds is a profound blend of art and science." This compound, like many others, represents the continuous quest for innovation in chemistry.

In summary, 2-(diethylamino)ethyl 2-ethoxy-5-fluoro-benzoate is not just another chemical; it embodies the intersection of creativity and scientific inquiry where each molecule unveils new possibilities.