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Lidocaine

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Identification
Molecular formula
C14H22N2O2
CAS number
137-58-6
IUPAC name
2-(diethylamino)ethyl 2-ethyl-2-methyl-hexanoate
State
State

At room temperature, lidocaine is present as a solid. In medical settings, it is often available in solution form, either as an injectable liquid or as a topical preparation such as cream or gel.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.00
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.00
General information
Molecular weight
234.34g/mol
Molar mass
234.3400g/mol
Density
1.0090g/cm3
Appearence

Lidocaine, in its pure form, is a white to slightly yellow crystalline powder. It is odorless and has a slight bitter taste. The compound is generally prepared for medical use in the form of a hydrochloride salt to enhance its solubility in water.

Comment on solubility

Solubility of 2-(diethylamino)ethyl 2-ethyl-2-methyl-hexanoate

The solubility of 2-(diethylamino)ethyl 2-ethyl-2-methyl-hexanoate is influenced by various factors due to its unique molecular structure. Here's what we know:

  • Polarity: This compound displays moderate polarity due to the presence of the diethylamino group, which can engage in hydrogen bonding.
  • Solvent Interaction: It tends to be soluble in organic solvents such as ethanol and acetone, demonstrating its affinity for non-polar environments.
  • Water Solubility: The solubility in water is limited, which can be attributed to the hydrophobic hydrocarbon chains that dominate the molecular structure.

When working with this compound, it is essential to consider the following:

  1. Testing solubility in various solvents to determine optimal conditions.
  2. Understanding the impact of temperature, as solubility may increase with elevated temperatures in organic solvents.
  3. Recognizing potential applications based on its solubility profile in industrial and pharmaceutical contexts.

In summary, while 2-(diethylamino)ethyl 2-ethyl-2-methyl-hexanoate has some solubility in organic solvents, its limited solubility in water underscores the need for careful selection of solvents in practical applications.

Interesting facts

Exploring 2-(Diethylamino)ethyl 2-ethyl-2-methyl-hexanoate

2-(Diethylamino)ethyl 2-ethyl-2-methyl-hexanoate is a fascinating chemical compound that belongs to the class of esters. This compound is notable for its unique structure and potential applications in various fields, particularly in pharmaceuticals and industrial chemistry. Here are some interesting facts:

  • Mechanism of Action: As an ester, this compound typically exhibits interesting interactions with biological systems, often influencing pharmaceutical properties such as solubility and permeability.
  • Functional Groups: The presence of the diethylamino group lends this compound its unique pharmacological profile, often enhancing its ability to interact with various biological targets.
  • Application Potential: Compounds similar to 2-(diethylamino)ethyl 2-ethyl-2-methyl-hexanoate are utilized in the synthesis of certain drugs and can serve as intermediates in organic synthesis, showcasing the versatility of esters.
  • Research Interest: Chemists are actively investigating compounds like this for their potential in developing new medications, including analgesics and anti-inflammatory agents.
  • Toxicology Profiling: As with many amine-containing compounds, understanding the safety and environmental impact is crucial. Toxicological studies can reveal the compound’s behavior in biological systems.
  • Structural Complexity: Its intricate molecular architecture makes it a subject of interest in synthetic organic chemistry, where researchers aim to develop novel reactions for creating complex molecules.

In summary, 2-(diethylamino)ethyl 2-ethyl-2-methyl-hexanoate exemplifies the intersection of organic chemistry and pharmacology. Its structural properties not only pique scientific interest but also hint at valuable applications in drug development and industrial use. The ongoing research in this field could lead to exciting advancements that improve therapeutic options or enhance manufacturing processes.