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Benzocaine hydrochloride

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Identification
Molecular formula
C17H21ClNO3
CAS number
23239-88-5
IUPAC name
2-(diethylamino)ethyl 2-hydroxy-3-phenyl-benzoate;hydrochloride
State
State

At room temperature, Benzocaine hydrochloride is in a solid state. The compound is hygroscopic, meaning it can absorb moisture from the air. It's generally stored in well-sealed containers to prevent it from absorbing water from the environment.

Melting point (Celsius)
217.00
Melting point (Kelvin)
490.15
Boiling point (Celsius)
252.00
Boiling point (Kelvin)
525.15
General information
Molecular weight
291.79g/mol
Molar mass
291.7930g/mol
Density
1.1750g/cm3
Appearence

The compound appears as a white, crystalline powder. It is typically odorless or has a faint characteristic odor. Its crystalline nature is well-defined, showing a solid form with distinct, fine particles.

Comment on solubility

Solubility of 2-(diethylamino)ethyl 2-hydroxy-3-phenyl-benzoate; hydrochloride

The solubility of 2-(diethylamino)ethyl 2-hydroxy-3-phenyl-benzoate; hydrochloride can be considered relatively favorable in polar solvents, particularly in water and alcohols, due to its ionic nature imparted by the hydrochloride form. Here are some key points regarding its solubility:

  • Water Solubility: This compound tends to be soluble in water because the presence of the hydrochloride group enhances its ability to interact with water molecules.
  • Alcohol Solubility: Soluble in alcohols, as these solvents can stabilize both polar and nonpolar parts of the molecule.
  • pH Dependency: Its solubility can vary with pH; in more acidic conditions, the hydrochloride form remains stable leading to increased solubility, whereas under basic conditions, it may precipitate out.
  • Organic Solvents: Limited solubility is expected in nonpolar organic solvents due to the presence of more polar functional groups.

In summary, the solubility characteristics of 2-(diethylamino)ethyl 2-hydroxy-3-phenyl-benzoate; hydrochloride make it highly versatile in diverse chemical environments, enabling its use in various applications. As the saying goes, "solubility is the key to reactivity!"

Interesting facts

Exploring 2-(Diethylamino)ethyl 2-hydroxy-3-phenyl-benzoate Hydrochloride

2-(Diethylamino)ethyl 2-hydroxy-3-phenyl-benzoate hydrochloride is a fascinating compound that integrates both pharmacological and industrial significance. Here are some interesting facts to consider:

  • Pharmaceutical Uses: This compound is frequently utilized in the pharmaceutical industry, particularly in the formulation of drugs that exhibit local anesthetic properties.
  • Mechanism of Action: It is known to function as a long-acting local anesthetic. By blocking sodium channels, this compound inhibits the transmission of nerve impulses, which is vital for pain management.
  • Chemical Structure: The presence of the diethylamino group provides the compound with its distinct electronic properties, making it unique compared to other related anesthetic agents.
  • Research Interest: Scientists are continuously investigating this compound for its potential applications beyond its anesthetic uses, including possible anti-cancer properties.
  • Safety and Regulation: As a hydrochloride salt, this compound is often noted for its improved solubility, which enhances its suitability for various formulations while emphasizing the importance of regulatory compliance in pharmaceutical use.

In summary, 2-(diethylamino)ethyl 2-hydroxy-3-phenyl-benzoate hydrochloride serves as a prime example of how chemical compounds can have far-reaching applications in medicine and research. As new studies emerge, the potential of this compound may continue to evolve, paving the way for novel therapeutic strategies.

Synonyms
BIPHENAMINE HYDROCHLORIDE
5560-62-3
Xenysalate hydrochloride
Biphenamine HCl
2-(Diethylamino)ethyl 2-hydroxy-3-biphenylcarboxylate hydrochloride
Biphenamine hydrochloride [USAN]
UNII-0WN4KYJ0C0
0WN4KYJ0C0
EINECS 226-930-9
(1,1'-Biphenyl)-3-carboxylic acid, 2-hydroxy-, 2-(diethylamino)ethyl ester, hydrochloride
DTXSID0063949
Biphenamine hydrochloride (USAN)
[1,1'-Biphenyl]-3-carboxylic acid, 2-hydroxy-, 2-(diethylamino)ethyl ester, hydrochloride
BIPHENAMINE HYDROCHLORIDE [MI]
XENYSALATE HYDROCHLORIDE [MART.]
(1,1'-Biphenyl)-3-carboxylic acid, 2-hydroxy-2-(diethylamino)ethyl ester, hydrochloride
.BETA.-DIETHYLAMINOETHYL-3-PHENYL-2-HYDROXYBENZOATE HYDROCHLORIDE
XENYSALATE HYDROCHLORIDE (MART.)
DTXCID1041926
BETA-DIETHYLAMINOETHYL-3-PHENYL-2-HYDROXYBENZOATE HYDROCHLORIDE
2-(diethylamino)ethyl 2-hydroxy-3-phenylbenzoate;hydrochloride
2-(DIETHYLAMINO)ETHYL 2-HYDROXY-3-BIPHENYLCARBOXYLATE HCL
Alvinine Shampoo
xenysalatehydrochlorid
SCHEMBL192932
CHEMBL2106552
IBBPBOICXYUQID-UHFFFAOYSA-N
AKOS030228523
NS00080870
A11568
D03127
Q27231198
Biphenamine hydrochloride 100 microg/mL in Acetonitrile
2-(DIETHYLAMINO)ETHYL2-HYDROXY-3-BIPHENYLCARBOXYLATEHCL
(1,1'-Biphenyl)-3-carboxylic acid, 2-hydroxy-, 2-(diethylamino)ethyl ester, hydrochloride (1:1)