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Lidocaine

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Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
2-(diethylamino)ethyl 2-phenylacetate
State
State

Lidocaine is primarily dispensed as a solid powder but is often used in a liquid form, either as a solution or gel, particularly in medical applications.

Melting point (Celsius)
68.00
Melting point (Kelvin)
341.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
235.34g/mol
Molar mass
235.3440g/mol
Density
1.0260g/cm3
Appearence

Lidocaine appears as a white crystalline powder, often available in solution form for medicinal usage. It is odorless and has a slightly bitter taste. The solutions for injection are usually clear and colorless.

Comment on solubility

Solubility of 2-(diethylamino)ethyl 2-phenylacetate

The solubility of 2-(diethylamino)ethyl 2-phenylacetate can be influenced by several factors, including its polarity and the nature of the solvent used. This compound, characterized by its diethylamino group and a phenylacetate moiety, exhibits interesting solubility properties:

  • Polar Solvents: Typically, compounds featuring amino groups tend to have higher solubility in polar solvents like water due to the potential for hydrogen bonding.
  • Non-polar Solvents: Conversely, the phenyl group suggests that 2-(diethylamino)ethyl 2-phenylacetate may also dissolve well in organic solvents, such as ether or chloroform, as the non-polar character of the aromatic ring enhances compatibility with non-polar solvents.
  • Miscibility: It is likely that this compound exhibits limited miscibility in water, mainly because the bulky diethylamino and phenyl groups create a steric hindrance that can affect solubility.

As a rule of thumb, “like dissolves like,” meaning that the nature of the solvent significantly affects whether the compound will dissolve. Thus, 2-(diethylamino)ethyl 2-phenylacetate should perform well in a variety of solvents, offering versatility in applications.

Overall, the solubility profile of this compound makes it an intriguing subject for further study in both pharmaceutical and chemical applications.

Interesting facts

Interesting Facts about 2-(Diethylamino)ethyl 2-phenylacetate

2-(Diethylamino)ethyl 2-phenylacetate is a compound that exhibits intriguing characteristics and applications that are of interest to both chemists and pharmacologists. Here are some fascinating aspects of this compound:

  • Structural Complexity: The compound features a unique structure that includes a diethylamino group, which contributes to its ability to interact with biological systems. This structural configuration is vital for its activity.
  • Pharmacological Significance: This compound is often studied for its potential as a pharmaceutical agent. Its involvement in medicinal chemistry opens the door to research into new drugs and therapeutic applications.
  • Mechanism of Action: Compounds like 2-(diethylamino)ethyl 2-phenylacetate can act on certain neurotransmitter systems, which might influence their effectiveness in treating various conditions. Understanding how it interacts at the molecular level can lead to innovative treatment strategies.
  • Synthetic Pathways: Chemists are interested in the synthesis of this compound, as it often involves multiple steps and specific reagents. This presents a practical exercise in organic synthesis for students and professionals alike.
  • Dimensional Awareness: The spatial arrangement of atoms in this compound could impact its overall behavior, particularly in biological environments. This aspect is crucial for understanding the pharmacodynamics and pharmacokinetics of the compound.
  • Research Frontiers: There is ongoing research into various derivatives of this compound, looking to enhance its efficacy or reduce potential side effects. This highlights the ever-evolving nature of chemical research.

In conclusion, 2-(diethylamino)ethyl 2-phenylacetate represents a compelling subject for investigation, not only due to its chemical properties but also because of its potential implications in health and medicine. As research continues, we may uncover even more applications that could benefit society.

Synonyms
2572-38-5
ACETIC ACID, PHENYL-, 2-(DIETHYLAMINO)ETHYL ESTER
NSC-165867
Phenylacetic acid 2-(diethylamino)ethyl ester
2-(diethylamino)ethyl 2-phenylacetate
NSC 165867
BRN 2108798
DP2EPM36UW
SCHEMBL8024258
DTXSID50180407
RWVYTYAOLUZVRV-UHFFFAOYSA-N
2-(diethylamino)ethyl phenylacetate
2-(Diethylamino)ethyl benzeneacetate
NSC165867
Phenylacetic acid, 2-diethylaminoethyl ester
Benzeneacetic acid, 2-(diethylamino)ethyl ester