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Lidocaine hydrochloride

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Identification
Molecular formula
C14H23ClN2O2
CAS number
6108-05-0
IUPAC name
2-(diethylamino)ethyl 2,2-diphenylacetate;hydrochloride
State
State

At room temperature, lidocaine hydrochloride is a solid. It is typically encountered in powder form, often used in its crystalline state for pharmaceutical applications.

Melting point (Celsius)
80.50
Melting point (Kelvin)
353.65
Boiling point (Celsius)
315.00
Boiling point (Kelvin)
588.15
General information
Molecular weight
288.82g/mol
Molar mass
288.8200g/mol
Density
1.0680g/cm3
Appearence

Lidocaine hydrochloride appears as a crystalline solid powder. It is usually white and can be found in a powdered form, often used in medical formulations.

Comment on solubility

Solubility of 2-(diethylamino)ethyl 2,2-diphenylacetate; hydrochloride

The solubility of the compound 2-(diethylamino)ethyl 2,2-diphenylacetate; hydrochloride (C14H23ClN2O2) is an important characteristic for its applications and impact in various chemical processes.

Key factors influencing solubility:

  • Ionic Nature: As a hydrochloride salt, it is expected to exhibit good solubility in polar solvents such as water due to the presence of ionic interactions.
  • Hydrophilic Groups: The presence of the amine and the carboxylate functionalities suggests the potential for favorable interactions with water molecules.
  • Hydrophobic Characteristics: The phenyl groups contribute to hydrophobicity, which may reduce solubility in nonpolar solvents.

Overall, while this compound is likely to be soluble in water, the degree of solubility can vary depending on factors like temperature and concentration. It is essential to test solubility under specific conditions to ascertain its behavior in various environments.

Summary

In summary, the solubility of 2-(diethylamino)ethyl 2,2-diphenylacetate; hydrochloride is influenced by its ionic nature and the balance between hydrophilic and hydrophobic moieties. Knowledge of its solubility profile is crucial for applications in pharmaceutical and chemical formulations.

Interesting facts

Interesting Facts about 2-(Diethylamino)ethyl 2,2-diphenylacetate; Hydrochloride

2-(Diethylamino)ethyl 2,2-diphenylacetate; hydrochloride is a fascinating compound with a variety of applications and implications in both pharmaceutical and academic fields. Here are some noteworthy aspects:

  • Pharmaceutical Relevance: This compound relates closely to drug development, demonstrating potential use as an anticholinergic agent. Anticholinergics are prominent in treating a variety of conditions, including muscle spasms and respiratory issues.
  • Structural Complexity: The presence of diethylamino and diphenylacetate groups positions this compound as a versatile scaffold for medicinal chemistry, enabling structural modifications to optimize biological activity.
  • Tertiary Amines: The incorporation of a diethylamino functional group showcases the significance of tertiary amines in biological systems, where their basicity can influence pharmacokinetics and dynamics.
  • Scientific Research: Ongoing studies often analyze this compound's activity within neuropharmacology, looking at how modifications can impact neurotransmitter regulation.
  • Historical Context: Similar compounds have led to advancements in understanding neurochemical pathways, demonstrating the importance of structure-activity relationships in organic chemistry.

This compound not only enhances our understanding of chemistry but also paves the way for innovative therapeutic approaches. As research continues, it promises to unveil more about its potential benefits and applications in medicine.

Synonyms
Adiphenine hydrochloride
50-42-0
ADIPHENINE HCL
Patrovina
Spasnil
Sentiv
Trasentin hydrochloride
Adiphenine chloride
Vegantin
Adiphen hydrochloride
Difacil hydrochloride
Adifenin hydrochloride
Adiphenine (hydrochloride)
Diphacil hydrochloride
Trasentine hydrochloride
Transentine hydrochloride
Adipheninium chloratum
Spasmolytin hydrochloride
Adiphenine hydrochloride [USAN]
2-(Diethylamino)ethyl diphenylacetate hydrochloride
Diphenylacetic acid 2-(diethylamino)ethyl ester hydrochloride
Diphenylacetyldiethylaminoethyl hydrochloride
UNII-42B4PDY0AV
EINECS 200-036-9
42B4PDY0AV
2-(diethylamino)ethyl 2,2-diphenylacetate hydrochloride
NSC 129224
NSC-129224
DTXSID0045880
Diphenylacetate du diethylamino-ethanol chlorhydrate
ACETIC ACID, DIPHENYL-, 2-(DIETHYLAMINO)ETHYL ESTER, HYDROCHLORIDE
MLS000028404
Diphenylacetate du diethylamino-ethanol chlorhydrate [French]
Adiphenine hydrochloride (USAN)
DTXCID8025880
Ethanol, 2-(diethylamino)-, 2,2-diphenylacetate, hydrochloride
Benzeneacetic acid, a-phenyl-, 2-(diethylamino)ethyl ester,hydrochloride
ADIPHENINE HYDROCHLORIDE [MI]
NSC129224
ADIPHENINE HYDROCHLORIDE [MART.]
NCGC00094995-01
ADIPHENINE HYDROCHLORIDE [WHO-DD]
SMR000058354
Benzeneacetic acid, .alpha.-phenyl-2-(diethylamino)ethyl ester hydrochloride
Benzeneacetic acid, alpha-phenyl-2-(diethylamino)ethyl ester hydrochloride
ADIPHENINE HYDROCHLORIDE (MART.)
CAS-50-42-0
Diphenylacetic acid 2-(diethylamino)ethyl ester
SR-01000000075
Prestwick_7
MFCD00050508
Opera_ID_604
Trasentine, hydrochloride
Benzeneacetic acid, alpha-phenyl-, 2-(diethylamino)ethyl ester, hydrochloride
REGID_for_CID_5763
SCHEMBL33478
MLS001076478
MLS002222150
SPECTRUM1503073
Adiphenine Hydrochloride, 98%
CHEMBL555654
HY-B0379AR
HY-B0379A
LKPINBXAWIMZCG-UHFFFAOYSA-N
HMS1568O11
HMS1922C11
Pharmakon1600-01503073
WLN: 2N2&2OVYR&R &GH
BCP22622
Tox21_111379
AC-013
CCG-39173
NSC758234
s2082
Adiphenine (hydrochloride) (Standard)
AKOS015900392
Tox21_111379_1
FA30127
NSC-758234
NCGC00016221-06
NCGC00094995-02
NCGC00094995-03
AS-15686
DA-50237
A2498
Adiphenine hydrochloride, analytical standard
Ethanol, 2,2-diphenylacetate, hydrochloride
NS00078962
SW196325-3
D02772
D88523
2-Diethylaminoethyl diphenylacetate hydrochloride
SR-01000000075-4
Q27258524
2-(diethylamino)ethyl 2,2-diphenylacetate;hydrochloride
2-(diethylamino)ethyl 2,2-diphenylacetate;hydron;chloride
Adiphenine HCl; NSC 129224; NSC-129224; NSC129224
200-036-9