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Proxymetacaine

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Identification
Molecular formula
C16H26N2O3
CAS number
5875-06-9
IUPAC name
2-(diethylamino)ethyl 3-methoxy-2-propoxy-benzoate
State
State

At room temperature, proxymetacaine is typically available as a liquid, primarily when formulated as eye drops. In its pure form, as a raw material, it may also exist as a crystalline solid, but it is most commonly distributed and used in solution.

Melting point (Celsius)
-10.00
Melting point (Kelvin)
263.15
Boiling point (Celsius)
370.30
Boiling point (Kelvin)
643.45
General information
Molecular weight
295.40g/mol
Molar mass
295.3820g/mol
Density
1.0080g/cm3
Appearence

Proxymetacaine, also known as Proparacaine, is generally available as a colorless to light yellow liquid in its pharmaceutical form. It is often sold as an eye drop solution that appears transparent.

Comment on solubility

Solubility of 2-(diethylamino)ethyl 3-methoxy-2-propoxy-benzoate

The solubility of 2-(diethylamino)ethyl 3-methoxy-2-propoxy-benzoate is an intriguing topic, as it can significantly influence its behavior in various chemical processes.

This compound exhibits moderate solubility in organic solvents, which can be attributed to its complex structure that includes both hydrophilic and hydrophobic components. Factors that affect its solubility include:

  • Polarity: The presence of the diethylamino group enhances solubility in polar solvent systems.
  • Hydrophobic Interactions: The methoxy and propoxy groups contribute to an increase in hydrophobic interactions, leading to lower solubility in water.
  • Temperature: Generally, an increase in temperature can improve solubility, especially in organic solvents.

Common solvents where this compound may show good solubility include:

  • Ethyl acetate
  • Methanol
  • Dichloromethane

Quote: "Like dissolves like" is an important principle to remember when predicting solubility. This means that the compound will likely be more soluble in nonpolar solvents than in polar solvents.

In summary, while 2-(diethylamino)ethyl 3-methoxy-2-propoxy-benzoate shows certain solubility characteristics, understanding the specific conditions and solvent systems involved can help in achieving optimal usage in practical applications.

Interesting facts

Exploring 2-(diethylamino)ethyl 3-methoxy-2-propoxy-benzoate

2-(diethylamino)ethyl 3-methoxy-2-propoxy-benzoate, often referred to in scientific circles simply as DEAE-MPB, is a fascinating compound with intriguing applications and properties. This chemical compound belongs to a class of esters that is particularly significant in medicinal chemistry and pharmaceutical synthesis.

Key Attributes and Applications

  • Pharmaceutical Relevance: This compound exhibits properties that have made it an area of interest for drug development, particularly as a potential therapeutic agent. Its unique molecular structure is attributed to its ability to interact favorably with biological systems.
  • Solubility Considerations: Its structure can influence solubility characteristics, making it ideal for various formulations, enhancing bioavailability in medicinal use.
  • Quaternary Amine Influence: The presence of the diethylamino group contributes to its effectiveness in drug activity by enhancing lipophilicity, allowing better penetration through biological membranes.

As a compound, DEAE-MPB demonstrates a balance of hydrophobic and hydrophilic properties, which is crucial for its role in biological interactions. The variance in chain lengths and functional groups signifies potential structure-activity relationships that can be optimized for specific therapeutic outcomes.

Interesting Facts

  • The methoxy and propoxy groups are significant for adjusting the electronic properties of the compound, potentially influencing its pharmacokinetics.
  • This compound can also serve as a versatile intermediate in organic synthesis, paving the way for innovative drug design and discovery.
  • Research into compounds like DEAE-MPB helps scientists understand mechanisms of cellular interaction, aiding in the development of targeted therapies.

In conclusion, 2-(diethylamino)ethyl 3-methoxy-2-propoxy-benzoate stands as an essential example of the complexity and potential that organic compounds can offer in the pursuit of therapeutic advancements. Its study not only enhances our chemical arsenal but also fuels innovative solutions to health challenges.