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Metoclopramide

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Identification
Molecular formula
C14H22ClN3O2
CAS number
364-62-5
IUPAC name
2-(diethylamino)ethyl 3-methyl-2-(2-methyl-4-oxo-quinazolin-3-yl)benzoate
State
State

Metoclopramide is typically found in its hydrochloride form at room temperature, appearing as a solid.

Melting point (Celsius)
147.50
Melting point (Kelvin)
420.65
Boiling point (Celsius)
423.50
Boiling point (Kelvin)
696.65
General information
Molecular weight
354.43g/mol
Molar mass
354.4340g/mol
Density
1.2660g/cm3
Appearence

Metoclopramide hydrochloride appears as a white or almost white powder. It is hygroscopic and is freely soluble in water, soluble in alcohol, sparingly soluble in acetone and practically insoluble in ether.

Comment on solubility

Solubility of 2-(diethylamino)ethyl 3-methyl-2-(2-methyl-4-oxo-quinazolin-3-yl)benzoate

The solubility of the compound 2-(diethylamino)ethyl 3-methyl-2-(2-methyl-4-oxo-quinazolin-3-yl)benzoate can be influenced by several factors, given its complex structure. Some key considerations include:

  • Polarity: This compound contains both polar and nonpolar regions. The diethylamino group is relatively polar, which may enhance solubility in polar solvents like water or alcohols.
  • Functional groups: The presence of the quinazolin-3-yl moiety might also affect its interaction with solvents, possibly lowering solubility in certain environments.
  • Temperature: Solubility can often increase with temperature. Therefore, heating solvents may improve the dissolution of this compound.
  • pH levels: Being a compound with possible ionizable groups, alterations in pH can lead to variations in solubility, particularly in aqueous solutions.

In summary, while specific solubility data might not be readily available, the compound’s unique structure suggests a potential for moderate solubility in a range of solvents, influenced primarily by polarity, functional groups, temperature, and pH levels. Further empirical testing would provide a clearer understanding of its solubility characteristics.

Interesting facts

Exploring 2-(diethylamino)ethyl 3-methyl-2-(2-methyl-4-oxo-quinazolin-3-yl)benzoate

This intriguing compound, 2-(diethylamino)ethyl 3-methyl-2-(2-methyl-4-oxo-quinazolin-3-yl)benzoate, belongs to a class of molecules known for their diverse biological activities. Here are some fascinating aspects to consider:

  • Pharmaceutical Relevance: Compounds similar to this one are often investigated for their potential as pharmacological agents, particularly in the fields of oncology and neurology.
  • Structural Complexity: The structure features a mixture of functional groups, including a benzoate and a quinazoline moiety, which are known to enhance binding affinity and selectivity towards biological targets.
  • Mechanism of Action: Many compounds in this category may function through mechanisms involving enzyme inhibition or receptor modulation, opening avenues for their use in therapeutic interventions.
  • Synthetic Utility: The preparation of such complex molecules often provides valuable insights into synthetic methodologies, including the use of coupling reactions and functional group transformations.
  • Research Interest: Ongoing studies may focus on how minor modifications in the structure can lead to significant changes in biological activity, making it a hot topic in medicinal chemistry.

As a compound of interest in the realm of scientific research, 2-(diethylamino)ethyl 3-methyl-2-(2-methyl-4-oxo-quinazolin-3-yl)benzoate exemplifies the intricate relationship between molecular structure and biological function. Cracking the code of its full potential could lead to breakthroughs in various therapeutic areas.