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Procaine

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Identification
Molecular formula
C13H20N2O2
CAS number
59-46-1
IUPAC name
2-(diethylamino)ethyl 4-amino-2,6-dimethyl-benzoate
State
State

At room temperature, procaine is typically found as a solid, either in powder form or as colorless crystalline pieces. It is stable under normal physical conditions but should be kept protected from light and moisture.

Melting point (Celsius)
61.00
Melting point (Kelvin)
334.20
Boiling point (Celsius)
203.50
Boiling point (Kelvin)
476.60
General information
Molecular weight
236.31g/mol
Molar mass
236.3080g/mol
Density
1.1000g/cm3
Appearence

Procaine appears as a white crystalline powder with no odor. It is known for its role as a local anesthetic and has a slightly bitter taste. When sold commercially, it may be in the form of a hydrochloride salt, which also appears as a white crystalline substance.

Comment on solubility

Solubility of 2-(diethylamino)ethyl 4-amino-2,6-dimethyl-benzoate

The solubility of a compound is a crucial property that influences its application and utility in various fields. For the compound 2-(diethylamino)ethyl 4-amino-2,6-dimethyl-benzoate, understanding its solubility helps predict how it will behave in different environments.

This compound exhibits a reasonable solubility profile in selected organic solvents. Here are some key points regarding its solubility:

  • Solvent Compatibility: It tends to dissolve well in non-polar and weakly polar solvents due to its organic nature, such as ethanol and chloroform.
  • Water Solubility: As a benzoate derivative, its solubility in water is limited. The presence of the bulky diethylamino group increases hydrophobic interactions, reducing solubility in aqueous solutions.
  • Temperature Dependence: Solubility can increase with temperature, which is an important consideration in reactions and applications.
  • pH Sensitivity: The solubility may also vary with pH, given the presence of amine groups that can exist in protonated or deprotonated forms, thus affecting water solubility.

In summary, while 2-(diethylamino)ethyl 4-amino-2,6-dimethyl-benzoate shows good solubility in organic solvents, its limited water solubility could restrict its application in aqueous environments. Always consider the interactions of the compound with solvents when assessing its utility and behavior in various chemical processes.

Interesting facts

2-(Diethylamino)ethyl 4-amino-2,6-dimethyl-benzoate

This compound is a noteworthy member of the class of amino benzoates, which are known for their intriguing applications and biological activity. Here are some captivating facts about 2-(diethylamino)ethyl 4-amino-2,6-dimethyl-benzoate:

  • Versatile Applications: The unique structure of this compound allows it to function in various fields. It is often explored in pharmaceutical research, particularly in the development of antidepressants and analgesics.
  • Biological Importance: Structurally similar compounds have exhibited notable biological activities, such as anti-inflammatory and anticancer properties. This raises interesting questions about the potential of 2-(diethylamino)ethyl 4-amino-2,6-dimethyl-benzoate as a lead compound for drug discovery.
  • Functional Groups: The presence of diethylamino and amino functional groups suggests that this compound may possess interesting amphiphilic properties, which can affect its interaction with biological membranes.
  • Synthetic Pathways: Researchers have developed several synthetic routes to produce such amino benzoates. This chemistry not only highlights the compound's importance but also provides insights into synthetic methods and the manipulation of chemical functionalities.
  • Structure-Activity Relationship (SAR): By studying the effects of modifications on this compound's structure, scientists can better understand the relationship between molecular structure and its biological effects, potentially leading to more effective drug designs.

In summary, 2-(diethylamino)ethyl 4-amino-2,6-dimethyl-benzoate is a compound that exemplifies the intersection of structure and biological function, making it a fascinating subject for both academic research and potential practical applications.

Synonyms
2-Diethylaminoethyl 4-amino-2,6-dimethylbenzoate
BRN 2123193
BENZOIC ACID, 4-AMINO-2,6-DIMETHYL-, 2-(DIETHYLAMINO)ETHYL ESTER
29446-94-4
4-Amino-2,6-dimethylbenzoic acid 2-(diethylamino)ethyl ester
DTXSID70183652
4-14-00-01712 (Beilstein Handbook Reference)
RefChem:327510
DTXCID10106143