Skip to main content

Benzocaine; Amoxicillin Hydrate

ADVERTISEMENT
Identification
Molecular formula
C9H11NO2; C16H19N3O5S
CAS number
89576-13-8
IUPAC name
2-(diethylamino)ethyl 4-aminobenzoate;(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;hydrate
State
State
The compound is typically in a crystalline solid state at room temperature with ingredients having different characteristics. It may also exist as a hydrate, affecting its solid state appearance.
Melting point (Celsius)
89.00
Melting point (Kelvin)
362.15
Boiling point (Celsius)
251.50
Boiling point (Kelvin)
524.65
General information
Molecular weight
369.40g/mol
Molar mass
369.4030g/mol
Density
1.2700g/cm3
Appearence

The compound is a white or almost white crystalline powder. It may sometimes appear as a crystalline solid with a slightly yellowish tint, depending on purity and exposure to light.

Comment on solubility

Solubility of 2-(diethylamino)ethyl 4-aminobenzoate

The solubility characteristics of 2-(diethylamino)ethyl 4-aminobenzoate are influenced by its molecular structure, which combines both hydrophilic and hydrophobic regions. This compound is moderately soluble in various organic solvents, thanks to the presence of the diethylamino group that facilitates interaction with non-polar solvents. However, its solubility in water is relatively low, which can be attributed to the large aromatic system that contributes to hydrophobic interactions.

General Considerations for Solubility

  • Polarity: The solubility is often improved in polar solvents, but the bulky groups can hinder full dissolution.
  • pH Sensitivity: As an amino compound, its solubility may vary significantly with pH changes, enhancing its solubility in acidic solutions.
  • Hydration Effects: The presence of a hydrate can impact solubility, potentially enhancing interactions with water molecules.

In summary, while 2-(diethylamino)ethyl 4-aminobenzoate presents some favorable solubility characteristics in organic media, its water solubility can be limited. As with many complex organic compounds, testing under varying conditions is essential for accurate solubility profiles.

Interesting facts

Interesting Facts about 2-(Diethylamino)ethyl 4-Aminobenzoate

This compound, also known for its complex structure and varied applications, is intriguing to chemists due to its dual functional character. Below are some of the compelling aspects of this particular compound:

  • Dual Activity: This compound exhibits both local anesthetic and anti-inflammatory properties, making it a valuable candidate in pharmaceuticals, particularly in pain management.
  • Structural Diversity: The presence of both a diethylamino group and a 4-aminobenzoate moiety enhances its ability to interact with biological targets. This variety in structure can lead to different pharmacological effects.
  • Chirality Matters: The chirality of certain components can significantly impact the efficacy and safety profile of this compound. Its specific stereochemistry (noted here as (2S,5R,6R)) plays a crucial role in how it interacts with receptors in the body.
  • Research Implications: The compound is of interest in ongoing research aimed at developing novel therapeutic agents. Scientists are exploring its potential in treating various conditions, including chronic pain and nerve injuries.

In the world of medicinal chemistry, compounds like this one represent the intersection of synthetic complexity and biological functionality. As one researcher notes, “The challenge lies not just in creating these compounds, but understanding their intricate behaviors in biological systems.”

Key Takeaways

Understanding the properties and potential applications of 2-(diethylamino)ethyl 4-aminobenzoate can lead to:

  • Innovative strategies in drug design.
  • New insights into pain management techniques.
  • Potential improvements in therapeutic outcomes.

In summary, this compound is a notable example of how chemical research continues to evolve, showcasing the promise of even the most complex molecules in designing future therapies.

Synonyms
6130-64-9
PENICILLIN G PROCAINE
Procaine penicillin
Duracillin A.S.
Procaine penicillin G monohydrate
Procaine penicillin G hydrate
Procaine penicilline G hydrate
Penicillin 100
Penicillin G procaine hydrate
Crysticillin a.s.
Penicillin G procaine [USP]
17R794ESYN
Benzoic acid, 4-amino-, 2-(diethylamino)ethyl ester, mono((2S,5R,6R)-3,3-dimethyl-7-oxo-6-((phenylacetyl)amino)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate), monohydrate
Penicillin G procaine (hydrate)
(2S,5R,6R)-3,3-Dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid compound with 2-(diethylamino)ethyl p-aminobenzoate (1:1) monohydrate
Crysticillin
Despacilina
Distaquaine
Ledercillin
Millicillin
Parencillin
Premocillin
Prostabillin
Afsillin
Aquacilina
Aquacillin
Aquasuspen
Avloprocil
Cilicaine
Duracillin
Kabipenin
Mylipen
Neoproc
Procanodia
Sharcillin
Wycillin
Depo-Penicillin
Penaquacaine G
Ampin-penicillin
Abbocillin-DC
Flo-Cillin
Pen-Fifty
Pro-pen
Diurnal-Penicillin
Flo-Cillin aqueous
Penicillin G procaine (USP)
Bactracillin G
NOVOCAINE PENICILLIN
2-(diethylamino)ethyl 4-aminobenzoate;(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;hydrate
Procaine benzylpenicillinate hydrate
Benzylpenicillin procaine monohydrate
UNII-17R794ESYN
Duracillin (TN)
Procaini benzylpenicillinum
Procaine Penicillin [BAN]
SCHEMBL18076
Benoic acid, 4-amino-, 2-(diethylamino)ethyl ester, mono((2S-(2alpha,5alpha,6beta))-3,3-dimethyl-7-oxo-6-((phenylacetyl)amino)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate), monohydrate
CHEMBL1200936
HY-N7120R
DTXSID40210207
PENICILLIN G PROCAINE [MI]
GAA13064
HY-N7120
s5515
PENICILLIN G PROCAINE [VANDF]
AKOS040742385
CCG-270158
DA-76705
MS-30508
PROCAINE BENZYLPENICILLIN [WHO-DD]
PROCAINE BENZYLPENICILLIN [WHO-IP]
PENICILLIN G PROCAINE [GREEN BOOK]
Penicillin G procaine (hydrate) (Standard)
PENICILLIN G PROCAINE [ORANGE BOOK]
CS-0099461
NS00076294
D02461
F82417
Penicillin G procaine salt hydrate, ~1000 U/mg
PROCAINI BENZYLPENICILLINUM [WHO-IP LATIN]
Q13026783