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Butamben

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Identification
Molecular formula
C17H27NO3
CAS number
94-25-7
IUPAC name
2-(diethylamino)ethyl 4-butoxybenzoate
State
State

At room temperature, Butamben is typically in a solid state as a crystalline powder.

Melting point (Celsius)
64.00
Melting point (Kelvin)
337.15
Boiling point (Celsius)
370.00
Boiling point (Kelvin)
643.15
General information
Molecular weight
265.40g/mol
Molar mass
265.3730g/mol
Density
1.0843g/cm3
Appearence

Butamben is typically a white, crystalline powder. It is odorless and has a characteristic bitter taste. Due to its powder form, it can become airborne if not handled properly, which might result in localized anesthetic effects if it comes into contact with the skin or mucous membranes.

Comment on solubility

Solubility of 2-(diethylamino)ethyl 4-butoxybenzoate

The solubility of 2-(diethylamino)ethyl 4-butoxybenzoate can be an intriguing topic due to the influence of its structural components. This compound, characterized by the presence of both hydrophilic and hydrophobic groups, exhibits unique solubility properties, particularly in different solvents.

Factors Affecting Solubility:

  • Polarity: The diethylamino group contributes a degree of polarity, while the butoxy and aromatic benzoate portions tend to be more hydrophobic.
  • Functional Groups: The ester functional group (from the benzoate) may enhance solubility in organic solvents.
  • Temperature: Like many organic compounds, solubility can increase with temperature, making it important to consider when conducting experiments.

In general, it is expected that 2-(diethylamino)ethyl 4-butoxybenzoate will show good solubility in:

  • Organic solvents such as ethanol, ethyl acetate, and chloroform.

Conversely, solubility in water is likely limited due to the hydrophobic characteristics of the butoxy group. It’s intriguing to note that the balance of these diverse interactions leads to the fascinating behavior of this compound in various solvents.

As a rule of thumb, “like dissolves like” should be a guiding principle to predict solubility outcomes effectively. Therefore, the application of this compound in practical scenarios often necessitates careful consideration of the solvent environment for optimal solubility.

Interesting facts

Interesting Facts About 2-(diethylamino)ethyl 4-butoxybenzoate

2-(diethylamino)ethyl 4-butoxybenzoate is an intriguing compound that belongs to the category of esters and features a unique combination of functional groups. Here are some interesting facets regarding this compound:

  • Applications in Pharmaceuticals: This compound may serve as an important building block in the synthesis of various pharmaceuticals, potentially enhancing drug delivery and efficacy.
  • Chemical Structure: Its structure showcases a diethylamino group attached to the ethyl chain, which can influence the solubility and bioactivity, allowing for tailored modifications in drug design.
  • Potential as a Surfactant: Due to its amphiphilic nature, it could possess surfactant properties, making it useful in formulations requiring emulsification or stabilization of mixtures.
  • Bench Chemistry: Compounds like 2-(diethylamino)ethyl 4-butoxybenzoate emphasize the importance of screening various analogs to identify optimal candidates for specific applications, such as increasing bioavailability in medicinal chemistry.
  • Exciting Research Opportunities: Current research may explore its role in neuropharmacology, given the presence of the diethylamino functional group, which is known to interact with neurotransmitter systems.

In summary, 2-(diethylamino)ethyl 4-butoxybenzoate is not merely a compound but a potential star in the realms of medicinal chemistry and material science. Its diverse applications, along with the intriguing chemical properties, make it a worthwhile subject for further investigation and study.

Synonyms
Butoxycaine
3772-43-8
2-(DIETHYLAMINO)ETHYL 4-BUTOXYBENZOATE
89M880K35B
UNII-89M880K35B
Benzoic acid, 4-butoxy-, 2-(diethylamino)ethyl ester (9CI, ACI); Benzoic acid, p-butoxy-, 2-(diethylamino)ethyl ester (6CI, 7CI, 8CI); 2-(Diethylamino)ethyl 4-butoxybenzoate; 2-(Diethylamino)ethyl 4-n-butoxybenzoate; Butoxycaine
BUTOXYCAINE [MI]
SCHEMBL25553
BUTOXYCAINE [WHO-DD]
benzoic acid,4-butoxy-,2-(diethylamino)ethyl ester
DTXSID50870957
DAA77243
NS00007026
2-DIETHYLAMINOETHYL-(P-BUTOXYBENZOATE)
Q27270050